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Tools to improve the diagnosis and management of T-cell mediated adverse drug reactions
Delayed drug T-cell immune-mediated hypersensitivity reactions have a large clinical heterogeneity varying from mild maculopapular exanthema (MPE) to severe cutaneous adverse reactions (SCARs) such as acute generalized exanthematous pustulosis (AGEP ...
Ana Maria Copaescu +8 more
doaj +1 more source
Delayed Hypersensitivity with Ferric Carboxymaltose [PDF]
Ferric Carboxymaltose (FCM) is widely used in the treatment of anaemia of Chronic Kidney Disease (CKD). The clinicians must be alert of the rare adverse events such as hypersensitivity with subsequent doses of FCM. Here, we report a case of a 59-year-old
Surabhi Sridhara +3 more
doaj +1 more source
Background Penicillins and other β-lactam antibiotics are the most common elicitors of allergic drug reaction. However, data on the pattern of clinical reaction types elicited by specific β-lactams are scarce and inconsistent.
Philipp Schrüfer +3 more
doaj +1 more source
Allergy skin testing with nonirritating concentrations of anesthetic agents [PDF]
Immediate hypersensitivity reactions to anesthetic agents are rare, but with a worrying morbidity and mortality rate. Allergy evaluation is mandatory when hypersensitivity reactions to anaesthetic agents are suspected.
Florin-Dan Popescu +5 more
doaj +1 more source
Alpha‐gal syndrome—Food or drug allergy: A case report
Key Clinical Message Alpha‐gal syndrome is an immunoglobulin E‐mediated hypersensitivity characterized by delayed allergic reactions to ingested products containing alpha‐gal carbohydrate.
Marina Božan +4 more
doaj +1 more source
DELAYED HYPERSENSITIVITY [PDF]
Exposure to picryl guinea pig albumin with 3–6 picryl groups per mole failed to affect the ability of peritoneal exudate or peripheral blood leukocytes from sensitized donors to transfer delayed sensitivity to normal recipients. In contrast, conjugates containing 40–48 picryl groups per mole altered the ability of exposed leukocytes to transfer delayed
John P Phair, Fred S Kantor
+4 more sources
Assessing delayed penicillin hypersensitivity using the PENFAST+ score
IntroductionApproximately 10% of individuals report a suspected allergy to penicillin, but according to allergy work-ups, only 10%–15% of them are truly allergic.
Julie Castagna +9 more
doaj +1 more source
Preserved cellular immunity in smoldering acute leukemia [PDF]
"Smoldering acute leukemia", a variant of acute myelogenous leukemia, has been recognized with frequent incidence in recent years. This is chracterized by benign clinical course, poor physical findings, leukopenia and mild anemia in the ...
Toki, Hironobu
core +1 more source
Anaphylaxis to levetiracetam in an adolescent: a very rare occurence
Background. Antiepileptic drugs (AEDs) are among the most common causes of severe delayed-type hypersensitivity reactions such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and Drug Reaction with Eosinophilia and Systemic ...
Şeyma Kahraman +7 more
doaj +1 more source
Contrast media (CM) are an indispensable part of modern medical imaging. Adverse reactions to CM are uncommon, but frequently involve cutaneous symptoms.
F. Tasker +4 more
semanticscholar +1 more source

