Results 31 to 40 of about 1,704,122 (259)

A U508C synonymous mutation in the SARS-CoV-2 deletion hotspot reduces deletion frequency and accelerates viral clearance

mBio
A deletion hotspot within the non-structural protein 1 (NSP1) gene (locus 500–532) has been observed in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes analyzed by next-generation sequencing.
Kaya Miyazaki, Akihiro Doi, Yuriko Tomita, Wataru Kamitani, Shutoku Matsuyama   +4 more
doaj   +1 more source

Graph-based data clustering: a quadratic-vertex problem kernel for s-Plex Cluster Vertex Deletion

, 2009
We introduce the s-Plex Cluster Vertex Deletion problem. Like the Cluster Vertex Deletion problem, it is NP-hard and motivated by graph-based data clustering.
Hannes Moser, René Van Bevern, Rolf Niedermeier   +2 more
core   +3 more sources

Tree Deletion Set has a Polynomial Kernel (but no OPT^O(1) approximation) [PDF]

, 2013
In the Tree Deletion Set problem the input is a graph G together with an integer k. The objective is to determine whether there exists a set S of at most k vertices such that G-S is a tree.
Giannopoulou, Archontia C., Lokshtanov, Daniel, Saurabh, Saket, Suchy, Ondrej   +3 more
core   +2 more sources

From karyotypes to precision genomics in 9p deletion and duplication syndromes

HGG Advances, 2022
While 9p deletion and duplication syndromes have been studied for several years, small sample sizes and minimal high-resolution data have limited a comprehensive delineation of genotypic and phenotypic characteristics.
Eleanor I. Sams, Jeffrey K. Ng, Victoria Tate, Ying-Chen Claire Hou, Yang Cao, Lucinda Antonacci-Fulton, Khadija Belhassan, Julie Neidich, Robi D. Mitra, F. Sessions Cole, Patricia Dickson, Jeffrey Milbrandt, Tychele N. Turner   +12 more
doaj   +1 more source

RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells [PDF]

, 2019
Cardiac mesenchymal stem cells (C-MSC) play a key role in maintaining normal cardiac function under physiological and pathological conditions. Glycolysis and mitochondrial oxidative phosphorylation predominately account for energy production in C-MSC ...
Jin, Yue, Kim, Il-man, Shen, Yan, Su, Xuan, Tang, Yaoliang, Weintraub, Neal L.   +5 more
core   +1 more source

Characteristics of four natural poliovirus type 1 variants with six-nucleotide deletion (2,783–2,788 nt) in the VP1 region

Microbiology Spectrum
Since the establishment of the Chinese acute flaccid paralysis (AFP) case surveillance system in 1999, around 7,200 strains of poliovirus (PV) type 1 have been identified and isolated.
Jie Lin, Lei Zhou, Chenglin Zhu, Jinhang Wei, Bo Lv, Yuan Si, Shuangli Zhu, Tianjiao Ji, Dongyan Wang, Qian Yang, Jinbo Xiao, Lan Yang, Kaitao Xiao, Kexin Shao, Yong Zhang, Dongmei Yan   +15 more
doaj   +1 more source

Isolation and Identification of Subgroup J Avian Leukosis Virus Inducing Multiple Systemic Tumors in Parental Meat-Type Chickens

Frontiers in Veterinary Science, 2021
Avian leukosis virus (ALV) continues evolving to obtain new genomic characters to enhance its pathogenicity. In the present study, an ALV-J strain LH20180301 was isolated from broiler breeder chickens that reached the speak of paralyzation before 20-week-
Ning Cui, Xuezhi Cui, Qinghua Huang, Shaohua Yang, Shuai Su, Chuantian Xu, Jianhe Li, Wenfeng Li, Chao Li   +8 more
doaj   +1 more source

Addition-Deletion Networks

, 2007
We study structural properties of growing networks where both addition and deletion of nodes are possible. Our model network evolves via two independent processes.
Abramowitz M, Ben-Naim E, Chung F, Cooper C, Durbin R, E Ben-Naim, Farid N, Huynen M A, Kimura M, Knuth D E, Lambiotte R, Mahmoud H M, Moreno Y, P L Krapivsky, Smythe R T, von Smoluchowski M, Waterman M S   +16 more
core   +1 more source

Abnormal Speech Motor Control in Individuals with 16p11.2 Deletions. [PDF]

, 2018
Speech and motor deficits are highly prevalent (>70%) in individuals with the 600 kb BP4-BP5 16p11.2 deletion; however, the mechanisms that drive these deficits are unclear, limiting our ability to target interventions and advance treatment.
Demopoulos, Carly, Fregeau, Brieana, Henderson-Sabes, Jennifer, Houde, John F, Kothare, Hardik, Mizuiri, Danielle, Nagarajan, Srikantan S, Sherr, Elliott H, Tjernagel, Jennifer   +8 more
core   +3 more sources

Effects of Δtor1 on Yeast Longevity via Chronological Lifespan Assay [PDF]

, 2017
TOR1 is known to extend chronological lifespan in S. cerevisiae. Δtor1 deletion was studied via chronological lifespan assay and environmental oxidative stress test.
Bestwick, Megan, Keyes, Amelia
core   +1 more source