Resistance to last-resort antibiotics in enterococci [PDF]
The genus Enterococcus comprises a diverse group of species, many of which are commensal members of the gut microbiota of humans and animals. The two most prominent species associated with humans, Enterococcus faecalis and Enterococcus faecium, have also
Allen, Freya +4 more
core +1 more source
Discovery of OJT008 as a Novel Inhibitor of Mycobacterium tuberculosis [PDF]
, 2022 Despite recent progress in the diagnosis of Tuberculosis (TB), the chemotherapeutic management of TB is still challenging. Mycobacterium tuberculosis (Mtb) is the etiological agent of TB, and TB is classified as the 13th leading cause of death globally ...
Onyenaka, Collins Chidi
core +1 more source
Fighting antimicrobial resistance in mycobacteria: development of an antivirulence screening platform and a genetic methodology to confirm drug resistance phenotypes [PDF]
, 2023 ¿RESUMENLa tuberculosis (TB) causó 10,6 millones de nuevos casos y 1,6 millones de muertes en 2021 según datos de la Organización Mundial de la Salud (OMS).
Calvet Seral, Juan +2 more
core
Decoding the WHO Global Tuberculosis Report 2024: A Critical Analysis of Global and Chinese Key Data [PDF]
The World Health Organization (WHO) “Global Tuberculosis Report 2024” underscores the ongoing challenges and progress in the global fight against tuberculosis (TB). Despite a slowdown in the annual increase in TB cases and a decline in TB-related deaths,
Guirong Wang +18 more
core +1 more source
Investigating the molecular mode of action of new series of antituberculosis compounds and the role of the Tap efflux pump in persistence and drug tolerance in mycobacteria [PDF]
, 2023 La tuberculosis sigue siendo hoy en día una de las enfermedades infecciosas más mortales a nivel mundial. Por ello, es necesario desarrollar nuevos fármacos con mecanismos de acción novedosos que sean eficaces frente a cepas multirresistentes de ...
Aínsa Claver, José Antonio +2 more
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Tuberculosis farmacorresistente: Mecanismos moleculares de Mycobacterium tuberculosis [PDF]
In this traditional review, we describe factors from both Mycobacterium tuberculosis (M. tb) and the host that are associated for tuberculosis drug-resistant.
García-Maldonado, José Q. +4 more
core +2 more sources
Molecular bases of cystic fibrosis [PDF]
, 2020 RESUMEN : La fibrosis quística (FQ) es una enfermedad monogénica autosómica recesiva con una prevalencia de 1/2500-3500 nacidos vivos. En 1989 se descubrió el gen CFTR responsable de la enfermedad: gen regulador de la conductancia transmembrana ...
Petitta, Benedetta
core
Antimicrobial Effect of Oxazolidinones and Its Synergistic Effect with Bedaquiline Against Mycobacterium abscessus Complex. [PDF]
Infect Drug Resist, 2023 Gao T +9 more
europepmc +1 more source
Treatment of Buruli ulcer: research, development, and repurposing of new therapeutics targeting Mycobacterium ulcerans [PDF]
Tese de doutoramento em Ciências da SaúdeMycobacterium ulcerans é o agente patogénico responsável pela Úlcera de Buruli, uma doença infeciosa tropical negligenciada.
Dominguez Enriquez, Juan Pablo
core
Advances in Diagnostics and Drug Discovery against Resistant and Latent Tuberculosis Infection. [PDF]
Pharmaceutics, 2023 Shleider Carnero Canales C +7 more
europepmc +1 more source