Results 31 to 40 of about 2,325 (179)

How HIV-1 Uses the Metabolite Inositol Hexakisphosphate to Build Its Capsid. [PDF]

Viruses
The HIV-1 capsid is one of virology's most iconic structures, yet how it assembles has long remained elusive. Remarkably, the capsid is made from just a single protein, CA, which forms a lattice of ~250 hexamers and exactly 12 pentamers.
James LC.
europepmc   +3 more sources

Soroprevalência e fatores de risco associados à leucose em bovinos de Villlavicencio, Colômbia [PDF]

Ciência Animal Brasileira, 2023
A leucose bovina é causada por um vírus oncogênico do gênero Deltaretrovirus, causando prejuízos associados à queda dos indicadores produtivos e restrições à exportação de bovinos e derivados.
Jhoan Conde-Muñoz, Natalia Reyes-Bernal, Maria Fernanda Guatibonza-Garzon, Julio Cesar Tobon, Diana Leal Valero, Blanca Lisseth Guzman Barragan   +5 more
doaj   +2 more sources

Genetic Variability of Bovine Leukemia Virus: Evidence of Dual Infection, Recombination and Quasi-Species [PDF]

Pathogens
We have characterized the intrahost genetic variation in the bovine leukemia virus (BLV) by examining 16 BLV isolates originating from the Western Siberia–Tyumen and South Ural–Chelyabinsk regions of Russia.
Aneta Pluta, Marzena Rola-Łuszczak, Federico G. Hoffmann, Irina Donnik, Maxim Petropavlovskiy, Jacek Kuźmak   +5 more
doaj   +2 more sources

Protease-mediated maturation of M-PMV reverse transcriptase into a functional heterodimer. [PDF]

Protein Sci
Abstract Reverse transcriptase (RT) of retroviruses orchestrates viral replication, yet its structural diversity remains poorly understood. Well‐studied RTs, such as those from HIV‐1, murine leukemia virus, and avian myeloblastosis virus, were characterized decades ago, but less prominent retroviruses have escaped detailed analysis.
Kapisheva M, Junková P, Vaněk O, Jalovcová Z, Křížová I, Dostálková A, Rumlová M.   +6 more
europepmc   +2 more sources

A broad wastewater screening and clinical data surveillance for virus-related diseases in the metropolitan Detroit area in Michigan [PDF]

Human Genomics
Background Periodic bioinformatics-based screening of wastewater for assessing the diversity of potential human viral pathogens circulating in a given community may help to identify novel or potentially emerging infectious diseases.
Yabing Li, Brijen Miyani, Russell A. Faust, Randy E. David, Irene Xagoraraki   +4 more
doaj   +2 more sources

Milk Macrophage Function in Bovine Leukemia Virus-Infected Dairy Cows

Frontiers in Veterinary Science, 2021
The implications of bovine leukemia virus (BLV) on innate and adaptive immune responses have been widely investigated; however, the effects of BLV on mammary gland immunity require further investigation.
Ewerton de Souza Lima, Ewerton de Souza Lima, Maiara Garcia Blagitz, Maiara Garcia Blagitz, Camila Freitas Batista, Alexandre José Alves, Artur Cezar de Carvalho Fernandes, Artur Cezar de Carvalho Fernandes, Eduardo Milton Ramos Sanchez, Eduardo Milton Ramos Sanchez, Hugo Frias Torres, Soraia Araújo Diniz, Marcos Xavier Silva, Alice Maria Melville Paiva Della Libera, Fernando Nogueira de Souza, Fernando Nogueira de Souza, Fernando Nogueira de Souza   +16 more
doaj   +1 more source

The Expression of Tax and HBZ Genes in Serum-Derived Extracellular Vesicles From HTLV-1 Carriers Correlates to Proviral Load and Inflammatory Markers

Frontiers in Microbiology, 2022
Human T-lymphotropic virus 1 (HTLV-1) is the etiologic agent of adult cell leukemia/lymphoma (ATL) and HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Debora Glenda Lima de La-Roque, Elaine Vieira Santos, Evandra Strazza Rodrigues, Péricles Natan Mendes da Costa, Verônica Soares Brauer, Fausto Almeida, Tissiana Marques de Haes, Osvaldo Massaiti Takayanagui, Dimas Tadeu Covas, Simone Kashima   +9 more
doaj   +1 more source

Impact of BoLA-DRB3 Polymorphisms on Clonality of Bovine Leukaemia Virus-Infected Cells of Cattle With Lymphoma. [PDF]

HLA
ABSTRACT Bovine leukaemia virus (BLV) infects cattle, integrates into the host genome as a provirus, and induces a persistent infection that remains asymptomatic but can cause leukaemia/lymphoma. Most BLV‐infected cell clones are created by massive depletion, and a few of these infected cell clones expand through the mitotic cycle, leading to the onset
Fukushi N, Yamanaka MP, Matsuura R, Watanuki S, Saito S, Matsumoto Y, Fukumoto K, Hosomichi K, Wang J, Takeshima SN, Aida Y.   +10 more
europepmc   +2 more sources

Investigating Infectious Organisms of Public Health Concern Associated with Wild Meat

Transboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
The wild meat trade poses a significant threat to public health as it facilitates the spillover of zoonotic pathogens through high‐risk activities such as the hunting, butchering, trade, and consumption of wild animals. Despite the health risks and association with marking epidemics including SARS, Ebola, and COVID‐19, the global wild meat trade ...
Georgia Kate Moloney, Philippe Gaubert, Sophie Gryseels, Erik Verheyen, Anne-Lise Chaber, Karima Al Salihi   +5 more
wiley   +1 more source

Diagnostic accuracy of Abbott Architect Assay as a screening tool for human T‐cell leukaemia virus type‐1 and type‐2 infection in a London teaching hospital with a large solid organ transplant centre

Transfusion Medicine, Volume 32, Issue 3, Page 256-260, June 2022., 2022
Abstract Aim In the United Kingdom, organ donors/recipients are screened for evidence of human T‐cell leukaemia virus type‐1 and type‐2 (HTLV‐1/2) infections. Since the United Kingdom is a low prevalence country for HTLV infections, a screening assay with high sensitivity and specificity is required.
Nathaniel Lee, Jamie Murphy, Rasheed Al‐Khudairi, Ann Sturdy, Tabitha Mahungu, Tanzina Haque, Paul Griffiths, Jennifer Tosswill, Dianne Irish   +8 more
wiley   +1 more source