Background Inflammation and altered lipid dyshomeostasis have been implicated in the pathogenesis of Alzheimer's disease and vascular dementia. Objective To determine if there are any associations between dietary patterns, plasma lipid profiles, and ...
Jun Dai +5 more
doaj +1 more source
Evidence of endothelial dysfunction in the development of Alzheimer's disease : Is Alzheimer's a vascular disorder? [PDF]
Acknowledgements Dr Soiza is funded by an NRS Career Research Fellowship.
Kelleher, Rory J., Soiza, Roy L
core +1 more source
Neuropsychiatric symptoms in 921 elderly subjects with dementia: a comparison between vascular and neurodegenerative types. [PDF]
Objective: i) to describe the neuropsychiatric profile of elderly subjects with dementia by comparing vascular (VaD) and degenerative dementias, i.e. dementia with Lewy bodies (DLB) and Alzheimer’s disease (AD); ii) to assess whether the severity and ...
Ballard C +14 more
core +1 more source
Objective Identifying modifiable factors influencing amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) risk is important for prevention. Blood biomarkers, particularly cholesterol, have been associated with neurodegenerative risk, but findings in ALS are inconsistent, and data on FTD are limited.
Christos V. Chalitsios +5 more
wiley +1 more source
Hemostasis biomarkers and incident cognitive impairment: the REGARDS study [PDF]
Essentials Cognitive disorders are increasing and vascular risk factors play a role in this. We performed a nested case control study of hemostasis biomarkers and cognitive impairment (CI). Higher baseline fibrinogen, factor VIII and D-dimer were related
Callas, P.W. +7 more
core +1 more source
Brain Atrophy Associated With Risk Variant rs10191329 Extends Beyond Multiple Sclerosis
The risk allele rs10191329*A is associated with disease severity and brain atrophy in people with multiple sclerosis (MS). We investigated the association of rs10191329 with age‐related brain atrophy in a population‐based cohort using 10,308 magnetic resonance imaging (MRI) scans of 4,815 participants aged ≥ 45 years without MS in cross‐sectional and ...
Cato E. A. Corsten +10 more
wiley +1 more source
Path Integration Changes as a Cognitive Marker for Vascular Cognitive Impairment?—A Pilot Study [PDF]
Path integration spatial navigation processes are emerging as promising cognitive markers for prodromal and clinical Alzheimer’s disease (AD). However, such path integration changes have been less explored in Vascular Cognitive Impairment (VCI), despite ...
Coughlan, Gillian +4 more
core +1 more source
Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt
As the population ages, certain neurodegenerative diseases (NDs) are becoming a major health issue. For this reason, this review will focus on the most common ND with onset after 65 years old; Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia.
Laura Ibanez +5 more
wiley +1 more source
Updating data on cognitive impairment in stroke patients
Vascular cognitive impairments are the expression of complex interactions between vascular etiology, risk factors (brain diseases, white matter lesions, etc.) and cellular changes at the brain level.
Denisa Floriana Vasilica Pîrșcoveanu +9 more
doaj +1 more source
The association of vascular disorders with incident dementia in different age groups
Background There is increasing evidence that dementia risk associated with vascular disorders is age dependent. Large population-based studies of incident dementia are necessary to further elucidate this effect.
Nienke Legdeur +6 more
doaj +1 more source

