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Clinics in Geriatric Medicine, 2018
Dementia with Lewy bodies (DLB) is the second most common neurodegenerative dementia following Alzheimer disease. It stems from the formation of Lewy bodies, which contain aggregates of the misfolded protein, α-synuclein. These deposit in areas of the nervous system and brain, leading to neuronal cell death and causing clinically apparent symptoms ...
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Dementia with Lewy bodies (DLB) is the second most common neurodegenerative dementia following Alzheimer disease. It stems from the formation of Lewy bodies, which contain aggregates of the misfolded protein, α-synuclein. These deposit in areas of the nervous system and brain, leading to neuronal cell death and causing clinically apparent symptoms ...
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Continuum, 2019
This article describes current diagnostic criteria relating to the diagnosis of Lewy body dementia, highlights diagnostic controversies, and reviews treatment approaches.Clinical diagnostic criteria for both Parkinson disease and dementia with Lewy bodies have been recently updated.
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This article describes current diagnostic criteria relating to the diagnosis of Lewy body dementia, highlights diagnostic controversies, and reviews treatment approaches.Clinical diagnostic criteria for both Parkinson disease and dementia with Lewy bodies have been recently updated.
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Distinguishing Lewy Body Dementia
Hospital Practice, 1998The presence of the distinctive formations known as Lewy bodies within brain cells has been linked to senile dementia. A pattern of clinical features helps distinguish Lewy body dementia from Alzheimer's and Parkinson's diseases. Differentiation can be important, because many patients with Lewy body dementia have a hypersensitivity to neuroleptic ...
L R, Lapalio, S S, Sakla
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Rivastigmine: Dementia with Lewy Bodies
Hospital Pharmacy, 2016This Hospital Pharmacy feature is extracted from Off-Label Drug Facts, a publication available from Wolters Kluwer Health. Off-Label Drug Facts is a practitioner-oriented resource for information about specific drug uses that are unapproved by the US Food and Drug Administration.
Kimberly A, Madson, Sherrill, Brown
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Pharmacotherapy of dementia with Lewy bodies
Expert Opinion on Pharmacotherapy, 2003The syndrome of dementia with Lewy bodies (DLB) is characterised by the clinical triad of fluctuating cognitive impairment, recurrent visual hallucinations and spontaneous motor features of Parkinsonism. In an attempt to define DLB as a distinct clinical syndrome separate from Alzheimer's disease (AD) and Parkinson's disease (PD) with dementia, a ...
Hubert H, Fernandez +2 more
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Dementia with Lewy Bodies: Neuropathology
Journal of Geriatric Psychiatry and Neurology, 2002The pathologic substrate of the clinical syndrome of dementia with Lewy bodies (DLB) remains to be determined. Only a few prospective clinicopathologic studies have been reported. In those reports, most cases of DLB had neocortical or limbic Lewy bodies and Alzheimer-type pathology below threshold for diagnosis of Alzheimer's disease. These results are
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Continuum
Lewy body dementia (LBD) is an umbrella term describing two closely related conditions: Parkinson disease dementia (PDD) and dementia with Lewy bodies (DLB). LBD is the second most common cause of neurodegenerative dementia but is often underrecognized in clinical practice.
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Lewy body dementia (LBD) is an umbrella term describing two closely related conditions: Parkinson disease dementia (PDD) and dementia with Lewy bodies (DLB). LBD is the second most common cause of neurodegenerative dementia but is often underrecognized in clinical practice.
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The Lewy Body Dementias: Dementia with Lewy Bodies and Related Syndromes
2017The Lewy body dementias comprise disorders characterized by parkinsonism and a dementia syndrome with a predominant attentional, executive and visuospatial component, and with the Lewy body as the core pathological marker. Dementia with Lewy bodies (DLB) and Parkinson’s disease with dementia (PDD) are two conditions that meet this definition and are ...
Sara Garcia-Ptacek +2 more
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Update on dementia with lewy bodies
Current Neurology and Neuroscience Reports, 2005Dementia with Lewy bodies (DLB) presents to a range of specialists and involves a number of management challenges. The nosologic status of the disorder is controversial, especially its clinical overlap with Parkinson's disease-related dementia and its pathologic distinction from Alzheimer's disease.
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