Results 81 to 90 of about 50,400 (305)

Research on the perspectives of people affected by dementia with Lewy bodies: a scoping review

Alzheimer’s Research & Therapy
Background Dementia with Lewy bodies (DLB) is associated with specific challenges, including heterogeneity in clinical presentation and a less favourable prognosis relative to other dementia subtypes.
Paula Sinead Donnelly, Aoife Sweeney, Anthony P. Passmore, Noleen K. McCorry, Joseph P. M. Kane   +4 more
doaj   +1 more source

Mitochondria and the Actin Cytoskeleton in Neurodegeneration

Cytoskeleton, EarlyView.
ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli, Preet Patel, Aneri Shethji, David Gau   +3 more
wiley   +1 more source

Characterizing Alzheimer’s Disease and Related Dementia in a Hypertension Population Within the State of Florida Using Electronic Health Record–Based Data

Clinical Pharmacology &Therapeutics, EarlyView.
Hypertension is a known modifiable risk factor for Alzheimer’s disease and related dementia (ADRD). However, it is unknown how variance in hypertension control, antihypertensive medications, and social determinants of health, such as social deprivation index (SDI), influence the risk of developing ADRD.
Eissa A. Jafari, Mona Alshahawey, Muhammad A. Zaman, Steven M. Smith, Yan Gong, Glenn E. Smith, Caitrin W. McDonough   +6 more
wiley   +1 more source

Relation of neuropathology with cognitive decline among older persons without dementia

Frontiers in Aging Neuroscience, 2013
Objective: Although it is now widely accepted that dementia has a long preclinical phase during which neuropathology accumulates and cognition declines, little is known about the relation of neuropathology with the longitudinal rate of change in ...
Patricia eBoyle, Lei eYu, Robert eWilson, Julie eSchneider, David Alan Bennett   +4 more
doaj   +1 more source

Dementia with Lewy bodies: association of Alzheimer pathology with functional connectivity networks [PDF]

, 2021
Julia Schumacher, Jeffrey L. Gunter, Scott A. Przybelski, David T. Jones, Jonathan Graff‐Radford, Rodolfo Savica, Christopher G. Schwarz, Matthew L. Senjem, Clifford R. Jack, Val J. Lowe, David S. Knopman, Julie A. Fields, Walter K. Kremers, Ronald C. Petersen, Neill R. Graff‐Radford, Tanis J. Ferman, Bradley F. Boeve, Alan Thomas, John‐Paul Taylor, Kejal Kantarci   +19 more
openalex   +1 more source

β-Amyloid PET and neuropathology in dementia with Lewy bodies

Neurology, 2019
Objective β-Amyloid (Aβ) pathology is common in patients with probable dementia with Lewy bodies (DLB). However, the pathologic basis and the differential diagnostic performance of Aβ PET are not established in DLB.
K. Kantarci, V. Lowe, Qin Chen, S. Przybelski, T. Lesnick, C. Schwarz, M. Senjem, J. Gunter, C. Jack, J. Graff‐Radford, David T. Jones, D. Knopman, N. Graff-Radford, T. Ferman, J. Parisi, D. Dickson, R. Petersen, B. Boeve, M. Murray   +18 more
semanticscholar   +1 more source

Novel clinicopathological characteristics differentiate dementia with Lewy bodies from Parkinson’s disease dementia

Neuropathology and Applied Neurobiology, 2020
Dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) known as Lewy body dementias have overlapping clinical and neuropathological features. Neuropathology in both includes combination of Lewy body and Alzheimer’s disease (AD) pathology.
D. Hansen, H. Ling, T. Lashley, J. Foley, C. Strand, Thamir M. Eid, J. Holton, T. Warner   +7 more
semanticscholar   +1 more source

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad, Abdulrahman A Alsayegh, Anjum Khanam, Awais Ahmed, António Raposo, Farkad Bantun, Md Zeyaullah, Ahmad O Babalghith, Abdullah F Aldairi, Boshra Mozaffar, Mohammed F Bajahzer, Mohamed H Abdelrahman, Mohammad Intakhab Alam   +12 more
wiley   +1 more source

Lewy body disease and dementia with Lewy bodies

Proceedings of the Japan Academy, Series B, 2014
In 1976 we reported our first autopsied case with diffuse Lewy body disease (DLBD), the term of which we proposed in 1984. We also proposed the term "Lewy body disease" (LBD) in 1980. Subsequently, we classified LBD into three types according to the distribution pattern of Lewy bodies: a brain stem type, a transitional type and a diffuse type.
openaire   +3 more sources

Early microglial activation and peripheral inflammation in dementia with Lewy bodies

Brain : a journal of neurology, 2018
The role of inflammation in dementia with Lewy bodies is unclear. Surendranathan et al. report that microglial activation is elevated in mild disease, before decreasing as cognition declines. Inflammatory markers in the blood are also altered compared to
A. Surendranathan, L. Su, E. Mak, L. Passamonti, Young T. Hong, R. Arnold, Patricia Vázquez Rodríguez, W. R. Bevan-Jones, Susannah A E Brain, T. Fryer, F. Aigbirhio, J. Rowe, J. O'Brien   +12 more
semanticscholar   +1 more source