Results 101 to 110 of about 43,841 (247)
Elevated Expression of Lanosterol 14α-Demethylase (CYP51) and the Synthesis of Oocyte Meiosis-Activating Sterols in Postmeiotic Germ Cells of Male Rats1 [PDF]
Maria Strömstedt+5 more
openalex +1 more source
Sulfonylamido Derivatives of 2-Aminophenoxathiin-10,10-Dioxide and Related Compounds Possess Antifungal Action Due to the Possible Inhibition of Lanosterol-14-α-Demethylase [PDF]
Claudiu T. Supuran+4 more
openalex +1 more source
EFFECT OF THE ORTHOSIPHON STAMINEUS, BENTH ON AMINOPYRINE METABOLISM IN RAT HEPATOCYTES [PDF]
One of the commonly used herbal medicines in Malaysia is Orthosiphon stamineus, Benth (family: Lamiaceae) or locally known as Misai Kucing. This experiment was undertaken to evaluate possible interaction of methanol extract of O.
CHIN JIN HAN1, ABAS HJ. HUSSIN
doaj
ABSTRACT The distribution of micro‐ and nanoplastics (MNPs) in the environment is increasingly becoming a cause of concern for human health. The small size of these particles makes them prone to accumulate not only in the tissues of various organs but also enables them to enter cells and act as carriers of external materials and microbes.
Alessandra Gianoncelli+11 more
wiley +1 more source
The R467K Amino Acid Substitution in Candida albicans Sterol 14α-Demethylase Causes Drug Resistance through Reduced Affinity [PDF]
David C. Lamb+3 more
openalex +1 more source
Histone H4K20 Demethylation by Two hHR23 Proteins
Summary: Histone methyl groups can be removed by demethylases. Although LSD1 and JmjC domain-containing proteins have been identified as histone demethylases, enzymes for many histone methylation states or sites are still unknown.
Xiongwen Cao+13 more
doaj
This study demonstrates that reducing the enzyme topoisomerase Top2 or its mammalian homolog TOP2B promotes longevity across multiple species, including yeast, worms, and mice. At the cellular/molecular level, TOP2B reduction mitigates the major cellular aging hallmarks such as epigenetic alterations, cell senescence, lysosomal biogenesis, and ...
Man Zhu+12 more
wiley +1 more source
The data have been obtained for tautomers and enantiomers of ATTAF-1 and ATTAF-2 that were developed based on antifungal standard drugs with triazole scaffold. These compounds were docked into the human and fungal lanosterol-14α-demethylase.
Hamid Irannejad+3 more
doaj
Repression ofAcinetobactervanillate demethylase synthesis by VanR, a member of the GntR family of transcriptional regulators [PDF]
Birgit Morawski+2 more
openalex +1 more source
Summary: The arginine methylation status of histones dynamically changes during many cellular processes, including hematopoietic stem/progenitor cell (HSPC) development.
Sihui Li+20 more
doaj