Results 101 to 110 of about 43,841 (247)

EFFECT OF THE ORTHOSIPHON STAMINEUS, BENTH ON AMINOPYRINE METABOLISM IN RAT HEPATOCYTES [PDF]

open access: yesMalaysian Journal of Pharmaceutical Sciences, 2007
One of the commonly used herbal medicines in Malaysia is Orthosiphon stamineus, Benth (family: Lamiaceae) or locally known as Misai Kucing. This experiment was undertaken to evaluate possible interaction of methanol extract of O.
CHIN JIN HAN1, ABAS HJ. HUSSIN
doaj  

Ovarian Cell Accumulation of Model PVC Nanoplastics Labelled With CdSe‐QDs Investigated by X‐Ray Fluorescence Microscopy

open access: yesX-Ray Spectrometry, EarlyView.
ABSTRACT The distribution of micro‐ and nanoplastics (MNPs) in the environment is increasingly becoming a cause of concern for human health. The small size of these particles makes them prone to accumulate not only in the tissues of various organs but also enables them to enter cells and act as carriers of external materials and microbes.
Alessandra Gianoncelli   +11 more
wiley   +1 more source

Histone H4K20 Demethylation by Two hHR23 Proteins

open access: yesCell Reports, 2020
Summary: Histone methyl groups can be removed by demethylases. Although LSD1 and JmjC domain-containing proteins have been identified as histone demethylases, enzymes for many histone methylation states or sites are still unknown.
Xiongwen Cao   +13 more
doaj  

Reduction of DNA Topoisomerase Top2 Reprograms the Epigenetic Landscape and Extends Health and Life Span Across Species

open access: yesAging Cell, EarlyView.
This study demonstrates that reducing the enzyme topoisomerase Top2 or its mammalian homolog TOP2B promotes longevity across multiple species, including yeast, worms, and mice. At the cellular/molecular level, TOP2B reduction mitigates the major cellular aging hallmarks such as epigenetic alterations, cell senescence, lysosomal biogenesis, and ...
Man Zhu   +12 more
wiley   +1 more source

Data on molecular docking of tautomers and enantiomers of ATTAF-1 and ATTAF-2 selectivty to the human/fungal lanosterol-14α-demethylase

open access: yesData in Brief, 2020
The data have been obtained for tautomers and enantiomers of ATTAF-1 and ATTAF-2 that were developed based on antifungal standard drugs with triazole scaffold. These compounds were docked into the human and fungal lanosterol-14α-demethylase.
Hamid Irannejad   +3 more
doaj  

JMJD1B Demethylates H4R3me2s and H3K9me2 to Facilitate Gene Expression for Development of Hematopoietic Stem and Progenitor Cells

open access: yesCell Reports, 2018
Summary: The arginine methylation status of histones dynamically changes during many cellular processes, including hematopoietic stem/progenitor cell (HSPC) development.
Sihui Li   +20 more
doaj  

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