Results 131 to 140 of about 93,436 (260)

Nanoparticles Enhance Solubility and Neuroprotective Effects of Resveratrol in Demyelinating Disease. [PDF]

Neurotherapeutics, 2023
Shamsher E, Khan RS, Davis BM, Dine K, Luong V, Somavarapu S, Cordeiro MF, Shindler KS.   +7 more
europepmc   +1 more source

The Genetic Landscape of Hereditary Spastic Paraplegia in Greece

Clinical Genetics, EarlyView.
We investigated 112 Greek index‐cases with hereditary spastic paraplegia collected over > 25 years using NGS and MLPA. We identified a causative variant in 68 patients (60.7%), including 7 novel causative variants. This study presents a comprehensive overview of the phenotypic and genotypic spectrum of HSP in the Greek population.
Georgios Koutsis, Viorica Chelban, Chrisoula Kartanou, Zoi Kontogeorgiou, Chrysoula Koniari, Nikolaos Ragazos, Charalampos Voudommatis, Kristina Zhelcheska, David S. Lynch, Reza Maroofian, Ehsan Barkhordari, Rahema Mohammad, Ioannis Zaganas, Minas Drakos, Georgia Xiromerisiou, Efthymios Dardiotis, Leonidas Stefanis, Marios Panas, Henry Houlden, Georgia Karadima   +19 more
wiley   +1 more source

Mechanisms of antigen-induced reversal of CNS inflammation in experimental demyelinating disease. [PDF]

Sci Adv, 2023
Li J, Lu L, Binder K, Xiong J, Ye L, Cheng YH, Majri-Morrison S, Lu W, Lee JW, Zhang Z, Wu YZ, Zheng L, Lenardo MJ.   +12 more
europepmc   +1 more source

Fall experiences of ambulatory children and adults with cerebral palsy: A qualitative study using thematic content analysis

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To qualitatively assess the causes, adaptations, and psychosocial impact of falls, and solutions for safer environments, as shared by individuals diagnosed with cerebral palsy (CP). Method Ambulatory adults with CP (n = 165; age median [interquartile range], range: 30 years [25–50], 18–76 years); 101 females, 59 males, five non‐binary/not ...
Marissa Esterley, Linda E. Krach, Kari Pederson, Sandy Callen Tierney, Nathan G. Wandersee, Elizabeth R. Boyer, on behalf of The Cerebral Palsy Research Network   +6 more
wiley   +1 more source

Post-COVID-19 Demyelinating Disease and Its Effect on the Lower Urinary Tract: A Rare Case of a 14-Year-Old Man. [PDF]

Cureus, 2023
Tsikopoulos I, Antoniadis G, Konstantinidis C, Samarinas M.   +3 more
europepmc   +1 more source

Preverbal visual assessment for screening cerebral visual impairment: Diagnostic accuracy and clinical utility

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To evaluate the relationship between Preverbal Visual Assessment (PreViAs) results and cerebral visual impairment (CVI) diagnosis. Method This single‐center retrospective chart review included children who completed a CVI interdisciplinary clinic or occupational therapy vision evaluation between May 2018 and May 2023 and had a completed ...
Karen L. Harpster, Terry L. Schwartz, Alaina Johnson, Reena Donofe, Li Lin, Melissa L. Rice   +5 more
wiley   +1 more source

Theiler's virus-induced demyelinating disease as an infectious model of progressive multiple sclerosis. [PDF]

Front Mol Neurosci, 2022
Pike SC, Welsh N, Linzey M, Gilli F.
europepmc   +1 more source

Ontologies for the study of neurological disease [PDF]

, 2012
We have begun work on two separate but related ontologies for the study of neurological diseases. The first, the Neurological Disease Ontology (ND), is intended to provide a set of controlled, logically connected classes to describe the range of ...
Cox, Alexander P., Diehl, Alexander D., Duncan, William, Jensen, Mark, Ruttenberg, Alan, Smith, Barry, Szigeti, Kinga, Weinstock-Guttman, Bianca   +7 more
core  

Conditional deletion of the multiple sclerosis susceptibility gene ATXN1 identifies cell‐autonomous effects in the B‐cell compartment

The FEBS Journal, EarlyView.
Ataxin‐1 is a polyglutamine protein associated with the etiology of spinocerebellar ataxia type 1 (SCA1) that has been recently found implicated in the risk of developing the autoimmune disorder multiple sclerosis (MS). Here, we took a conditional knockout approach to ablate ataxin‐1 exclusively in the B‐cell compartment and we found that this protein ...
Jonathan Jacob Carver, Rachael Riley Denbrock, Cindy Carolina Martines, Alessandro Didonna   +3 more
wiley   +1 more source

Unusual Demyelinating Disease of the Central Nervous System Involving Bilateral Corticospinal Tracts Following COVID-19 Infection: A Case Report. [PDF]

J Clin Neurol, 2023
Ju H, Kim YH, Seok JM, Kim BJ.
europepmc   +1 more source