Results 51 to 60 of about 67,279 (165)
PLoS ONE, 2014 IntroductionOnset of MS occurs during childhood in about 5% of cases. It is unclear whether very young age at MS onset, when the nervous system is still myelinating, affects MS lesion accrual or regional distribution.ObjectiveTo compare the frequency ...
Rezwan Ghassemi +6 more
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Magnetic resonance imaging in five patients with a tumefactive demyelinating lesion in the central nervous system [PDF]
Arquivos de Neuro-Psiquiatria, 1999 Five patients with a tumefactive lesion were clinically followed from 1992 to 1993. Four patients were female; age ranged from 32 to 57 years, the duration of symptoms varied from 3 days to 3 years.
HELGA C. ALMEIDA SILVA +4 more
doaj +1 more source
Self-supervised Lesion Change Detection and Localisation in Longitudinal Multiple Sclerosis Brain Imaging [PDF]
arXiv, 2021 Longitudinal imaging forms an essential component in the management and follow-up of many medical conditions. The presence of lesion changes on serial imaging can have significant impact on clinical decision making, highlighting the important role for automated change detection.
arxiv
Brain-Derived Neurotrophic Factor in Multiple Sclerosis Disability: A Prospective Study
Brain SciencesMultiple sclerosis (MS) is a demyelinating central nervous system disease that leads to neurological disability. Brain-derived neurotrophic factors (BDNFs) are neurotrophins involved in neurodegenerative disorders.
Vitalie Vacaras +9 more
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Computational Reproducibility in Metabolite Quantification Applied to Short Echo Time in Vivo MR Spectroscopy [PDF]
IEEE International Symposium on Biomedical Imaging, Apr 2023,
Cartagena de Indias, France, 2023 In vivo metabolite quantification by short echo time MR spectroscopy is a challenge for which various methods have been proposed. In this study, the reproducibility of quantification outcomes is questioned at three distinct levels: (i) between-software (LCModel and cQUEST), (ii) withinsoftware (with different parameter sets), and (iii) across software ...
arxiv
Frontiers in Genetics, 2019 Exosomes can pass through the blood-brain barrier and are present in the cerebrospinal fluid (CSF). The components in exosomes, such as DNA, RNA, protein, and lipids, change greatly and are closely related to disease progression.
Jinting He +6 more
doaj +1 more source
Forecasting Disease Burden In Philippines: A Symbolic Regression Analysis [PDF]
arXiv, 2021 Burden of disease measures the impact of living with illness and injury and dying prematurely and it is increasing worldwide leading cause of death both global and national. This paper aimed to propose an index of diseases and evaluate a mathematical model to describe the number of burden of disease by cause in the Philippines from 1990 - 2016. Through
arxiv
P2T2: a Physically-primed deep-neural-network approach for robust $T_{2}$ distribution estimation from quantitative $T_{2}$-weighted MRI [PDF]
arXiv, 2022 Estimating $T_2$ relaxation time distributions from multi-echo $T_2$-weighted MRI ($T_2W$) data can provide valuable biomarkers for assessing inflammation, demyelination, edema, and cartilage composition in various pathologies, including neurodegenerative disorders, osteoarthritis, and tumors.
arxiv
Parkinsonism and neurosarcoidosis: Cause and effect or coincidence?
Clinical Parkinsonism & Related Disorders, 2019 Movement disorders in demyelinating diseases can be coincidental or secondary to a demyelinating lesion. We here report the first case of coincidental association of neurosarcoidosis and idiopathic Parkinson's disease.
Raja Mehanna, Lael Stone, Ilia Itin
doaj
Akt3-Mediated Protection Against Inflammatory Demyelinating Disease
Frontiers in Immunology, 2019 Akt is a serine/threonine protein kinase that plays a major role in regulating multiple cellular processes. While the isoforms Akt1 and Akt2 are involved in apoptosis and insulin signaling, respectively, the role for Akt3 remains uncertain.
Juwen C. DuBois +6 more
doaj +1 more source