Results 11 to 20 of about 44,319 (309)

Recognizing early MRI signs (or their absence) is crucial in diagnosing metachromatic leukodystrophy

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1999-2009, December 2022., 2022
Abstract Objectives Metachromatic leukodystrophy (MLD) has characteristic white matter (WM) changes on brain MRI, which often trigger biochemical and genetic confirmation of the diagnosis. In early or pre‐symptomatic disease stages, these typical MRI changes might be absent, hampering early diagnosis.
Daphne H. Schoenmakers, Shanice Beerepoot, Ingeborg Krägeloh‐Mann, Saskia Elgün, Benjamin Bender, Marjo S. van der Knaap, Nicole I. Wolf, Samuel Groeschel   +7 more
wiley   +1 more source

Specific myeloid signatures in peripheral blood differentiate active and rare clinical phenotypes of multiple sclerosis

Frontiers in Immunology, 2023
Current understanding of Multiple Sclerosis (MS) pathophysiology implicates perturbations in adaptive cellular immune responses, predominantly T cells, in Relapsing-Remitting forms (RRMS).
Aigli G. Vakrakou, Aigli G. Vakrakou, Nikolaos Paschalidis, Eleftherios Pavlos, Eleftherios Pavlos, Christina Giannouli, Dimitris Karathanasis, Xristina Tsipota, Georgios Velonakis, Christine Stadelmann-Nessler, Maria-Eleftheria Evangelopoulos, Leonidas Stefanis, Constantinos Kilidireas, Constantinos Kilidireas   +13 more
doaj   +1 more source

Recurrent Fulminant Tumefactive Demyelination With Marburg-Like Features and Atypical Presentation: Therapeutic Dilemmas and Review of Literature

Frontiers in Neurology, 2020
Atypical forms of demyelinating diseases with tumor-like lesions and aggressive course represent a diagnostic and therapeutic challenge for neurologists.
Aigli G. Vakrakou, Dimitrios Tzanetakos, Theodore Argyrakos, Georgios Koutsis, Maria-Eleptheria Evangelopoulos, Elisabeth Andreadou, Maria Anagnostouli, Marianthi Breza, John S. Tzartos, Elias Gialafos, Antonios N. Dimitrakopoulos, Georgios Velonakis, Panagiotis Toulas, Leonidas Stefanis, Constantinos Kilidireas   +14 more
doaj   +1 more source

Heterogeneity of Baló’s concentric sclerosis: a study of eight cases with different therapeutic concepts

BMC Neurology, 2020
Background Baló’s Concentric Sclerosis (BCS) is a rare heterogeneous demyelinating disease with a variety of phenotypes on Magnetic Resonance Imaging (MRI).
D. Tzanetakos, A. G. Vakrakou, J. S. Tzartos, G. Velonakis, M. E. Evangelopoulos, M. Anagnostouli, G. Koutsis, E. Dardiotis, E. Karavasilis, P. Toulas, L. Stefanis, C. Kilidireas   +11 more
doaj   +1 more source

Electroneurophysiological criteria of efficiency of pathogenetic therapy in diabetic polyneuropathy. [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy, 2016
Purpose: to estimate efficiency of pathogenetic therapy of diabetic polyneuropathy with including of benfotiaminby means of an electroneuromyography.
Lubov Kuzina, Gulnaz Kaishibayeva
doaj   +1 more source

The Role of Visual Evoked Potentials in the Differential Diagnosis of Demyelinating Diseases

Türk Nöroloji Dergisi, 2021
Objective: Demyelinating diseases are included in the differential diagnosis of non-specific white matter lesions (NSWMLs), which are incidentally detected by magnetic resonance imaging (MRI) of the brain.
Nurhan Kaya Tutar, Sami Ömerhoca, Elif Söylemez, Turgut Adatepe, Nilüfer Kale   +4 more
doaj   +1 more source

The role of glial cells in neurodegenerative diseases. Part 2. Glial cells pathophysiology in neurodegeneration [PDF]

Farmacja Polska, 2022
The proper operation of the nervous system is strongly dependent on the interactions between neurons and glial cells. Thus, the disturbance of their relationship leads to various neurological complications.
Mateusz Maszczyk, Sara Lechowska, Dorota Wrześniok   +2 more
doaj   +1 more source

Utility of cerebrospinal fluid liquid biopsy in distinguishing CNS lymphoma from cerebrospinal infectious/demyelinating diseases

Cancer Medicine, 2023
Background Distinguishing between central nervous system lymphoma (CNSL) and CNS infectious and/or demyelinating diseases, although clinically important, is sometimes difficult even using imaging strategies and conventional cerebrospinal fluid (CSF ...
Chisako Iriyama, Kenichiro Murate, Sachiko Iba, Akinao Okamoto, Naoe Goto, Hideyuki Yamamoto, Toshiharu Kato, Keichiro Mihara, Takahiko Miyama, Keiko Hattori, Ryoko Kajiya, Masataka Okamoto, Yasuaki Mizutani, Seiji Yamada, Tetsuya Tsukamoto, Yuichi Hirose, Tatsuro Mutoh, Hirohisa Watanabe, Akihiro Tomita   +18 more
doaj   +1 more source

The role of glial cells in neurodegenerative diseases. Part 1. Characteristics and physiological functions [PDF]

Farmacja Polska, 2022
The nervous system is composed of two dominant types of cells – neurons and glial cells. They differ from each other both morphologically and physiologically.
Mateusz Maszczyk, Sara Lechowska, Dorota Małgorzata Wrześniok   +2 more
doaj   +1 more source

Demyelination in rheumatic diseases [PDF]

Postgraduate Medical Journal, 2008
Abstract Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterised by multifocal areas of demyelination in the white matter of the brain and spinal cord. Autoantibodies, for example antinuclear antibodies, can also be present.
A Theodoridou, Loukas Settas
openaire   +4 more sources