Results 231 to 240 of about 9,029,710 (297)
Experimental Models of Autoimmune Demyelinating Diseases in Nonhuman Primates
L. Stimmer+2 more
semanticscholar +1 more source
Abstract Plasma‐derived medicinal products (PDMPs), particularly immunoglobulins (Igs), are essential treatments for numerous diseases, often serving as the primary therapeutic option and playing a critical role in patient care. The human origin of these products, however, can lead to supply constraints due to a lack of plasma collection, market ...
Miriam Belmonte+4 more
wiley +1 more source
Several household chemical exposures are associated with pediatric‐onset multiple sclerosis [PDF]
et al,, Goyal, Manu, Mar, Soe
core +1 more source
Psychiatric disorders in children with demyelinating diseases of the central nervous system
J. Pakpoor+5 more
semanticscholar +1 more source
Chapter 4 B Cells and Autoantibodies in the Pathogenesis of Multiple Sclerosis and Related Inflammatory Demyelinating Diseases [PDF]
Katherine A. McLaughlin+1 more
openalex +1 more source
Main Points Ablation of autophagy in oligodendrocytes reveals increased PLP expression, myelin abnormalities, axon degeneration and increased microglia activation in aged mice. The aged mice exhibit marked deficits in learning and memory tasks. ABSTRACT The aging central nervous system (CNS) is often marked by myelin degeneration, yet the underlying ...
Niki Ktena+8 more
wiley +1 more source
Myelin basic protein-specific T lymphocytes proliferation and programmed cell death in demyelinating diseases [PDF]
Marina Saresella+9 more
openalex +1 more source
Characterizing Diagnostic Delays in Metachromatic Leukodystrophy: A Real‐World Data Approach
ABSTRACT Neurodegeneration in metachromatic leukodystrophy (MLD) may be preceded by systemic complications. Characterization of these features is critical to define barriers to early diagnosis and treatment eligibility for gene therapy. We utilized medical billing (claims) datasets and a natural history study to capture pre‐diagnosis MLD‐related events.
Ali Mohajer+5 more
wiley +1 more source
Pelvic Pain as an Unusual First Presentation of a Demyelinating Disease [PDF]
Anthony L. Loschner, John E. Snyder
openalex +1 more source