Results 231 to 240 of about 9,029,710 (297)

Experimental Models of Autoimmune Demyelinating Diseases in Nonhuman Primates

open access: yesVeterinary Pathology-Supplement, 2018
L. Stimmer   +2 more
semanticscholar   +1 more source

Understanding supply sustainability of plasma‐derived medicinal products: Drivers and consequences of shortages

open access: yesVox Sanguinis, EarlyView.
Abstract Plasma‐derived medicinal products (PDMPs), particularly immunoglobulins (Igs), are essential treatments for numerous diseases, often serving as the primary therapeutic option and playing a critical role in patient care. The human origin of these products, however, can lead to supply constraints due to a lack of plasma collection, market ...
Miriam Belmonte   +4 more
wiley   +1 more source

Psychiatric disorders in children with demyelinating diseases of the central nervous system

open access: yesMultiple Sclerosis, 2018
J. Pakpoor   +5 more
semanticscholar   +1 more source

Disruption of Oligodendroglial Autophagy Leads to Myelin Morphological Deficits, Neuronal Apoptosis, and Cognitive Decline in Aged Mice

open access: yesGlia, Volume 73, Issue 7, Page 1383-1397, July 2025.
Main Points Ablation of autophagy in oligodendrocytes reveals increased PLP expression, myelin abnormalities, axon degeneration and increased microglia activation in aged mice. The aged mice exhibit marked deficits in learning and memory tasks. ABSTRACT The aging central nervous system (CNS) is often marked by myelin degeneration, yet the underlying ...
Niki Ktena   +8 more
wiley   +1 more source

Myelin basic protein-specific T lymphocytes proliferation and programmed cell death in demyelinating diseases [PDF]

open access: green, 2008
Marina Saresella   +9 more
openalex   +1 more source

Characterizing Diagnostic Delays in Metachromatic Leukodystrophy: A Real‐World Data Approach

open access: yesJournal of Inherited Metabolic Disease, Volume 48, Issue 4, July 2025.
ABSTRACT Neurodegeneration in metachromatic leukodystrophy (MLD) may be preceded by systemic complications. Characterization of these features is critical to define barriers to early diagnosis and treatment eligibility for gene therapy. We utilized medical billing (claims) datasets and a natural history study to capture pre‐diagnosis MLD‐related events.
Ali Mohajer   +5 more
wiley   +1 more source

CD154 Blockade Results in Transient Reduction in Theiler's Murine Encephalomyelitis Virus-Induced Demyelinating Disease

open access: green, 2003
Laurence M. Howard   +4 more
openalex   +1 more source

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