Results 21 to 30 of about 44,319 (309)

RESULTS OF AN OPEN-LABEL COMPARATIVE RANDOMIZED CLINICAL TRIAL OF AXOGLATIRAN® FS (F-SINTEZ, RUSSIA) EFFICIENCY AND SAFETY IN COMPARISON WITH COPAXONE®-TEVA (TEVA PHARMACEUTICAL INDUSTRIES LTD., ISRAEL) IN PATIENTS WITH RELAPSING-REMITTING MULTIPLE SCLEROSIS

Нервно-мышечные болезни, 2017
Objective. Comparison of Axoglatiran® FS (F-Sintez,  Russia) and Copaxone®-Teva (Teva Pharmaceutical Industries Ltd.,  Israel) efficiency and safety in patients with relapsing-remitting multiple sclerosis. Materials and methods. In the study 150 patients
F. A. Khabirov, T. I. Khaibullin, E. V. Granatov, N. N. Babicheva, L. A. Aver’yanova, S. R. Shakirzyanova   +5 more
doaj   +1 more source

Psychiatric manifestations of multiple sclerosis and acute disseminated encephalomyelitis [PDF]

, 2006
It is unusual for acute disseminated encephalomyelitis and multiple sclerosis to present as purely psychiatric disorders. We report five patients with such demyelinating diseases and symptoms of psychosis, depression or anxiety.
Brinar, Marko, Brinar, Vesna V., Habek, Mario, Poser, Charles M.   +3 more
core   +1 more source

Magnetic Resonance Imaging of Autoimmune Demyelinating Diseases as a Diagnostic Challenge for Radiologists: Report of Two Cases and Literature Review

Life, 2022
The magnetic resonance characteristics of autoimmune demyelinating diseases are complex and represent a challenge for the radiologist. In this study we presented two different cases of detected autoimmune demyelinating diseases: one case of acute ...
Antonio Pierro, Alessandro Posa, Tiziana Addona, Antonella Petrosino, Vittorio Galasso, Alessandro Tanzilli, Sara Niro, Fernando Antonio Simone, Savino Cilla, Roberto Iezzi   +9 more
doaj   +1 more source

RP-CARS reveals molecular spatial order anomalies in myelin of an animal model of Krabbe disease [PDF]

Journal of Biophotonics 10 (2017) 385-393, 2020
Krabbe disease (KD) is a rare demyelinating sphingolipidosis, often fatal in the first years of life. It is caused by the inactivation of the galactocerebrosidase (GALC) enzyme that causes an increase in the cellular levels of psychosine considered to be at the origin of the tissue-level effects.
arxiv   +1 more source

Viral-induced neurodegenerative disease. [PDF]

, 1999
Viral etiology has been postulated in a variety of neurological diseases in humans, including multiple sclerosis. Several experimental animal models of viral-induced neurodegenerative disease provide insight into potential host- and pathogen-dependent ...
Buchmeier, MJ, Lane, TE
core   +1 more source

Endothelin-1 contributes to the development of virus-induced demyelinating disease

Journal of Neuroinflammation, 2020
Background Experimental autoimmune encephalitis (EAE) and virally induced demyelinating disease are two major experimental model systems used to study human multiple sclerosis.
Young-Hee Jin, Bongsu Kang, Hyun S. Kang, Chang-Sung Koh, Byung S. Kim   +4 more
doaj   +1 more source

PAF‐induced inflammatory and immuno‐allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects

BioFactors, Volume 48, Issue 6, Page 1226-1249, November/December 2022., 2022
Abstract Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and microbes pervade our environment. Inflammatory and allergic mediators released by dendritic and mast cells within the conjunctiva cause allergic conjunctivitis (AC), a prevalent ocular surface disorder that affects >40% of the world's human population on a ...
Najam A. Sharif
wiley   +1 more source

Diagnosis of inflammatory demyelination in biopsy specimens: a practical approach [PDF]

, 2008
Multiple sclerosis is the most frequent demyelinating disease in adults. It is characterized by demyelination, inflammation, gliosis and a variable loss of axons.
A Gallo, A Gocht, A Harder, A Johnson, A Omuro, A Ormsby, A Plonquet, A Pohl-Koppe, A Vagal, A Vincent, AJ Ferreri, BA Carlson, BK Kleinschmidt-DeMasters, BK Kleinschmidt-DeMasters, BL Padgett, C Buckley, C Johns, C Liew, C Lucchinetti, C Sinclair, CA Pardo, CF Lucchinetti, CG Bien, D Anderson, D Rodriguez, D Younger, DW Hanto, GM ZuRhein, H Budka, H Moser, Hans Lassmann, J Bauer, J Jennette, J Mosser, J Smith, JL Hynson, JM Powers, K Aström, K Brecher, K Dörries, K Haren Van, K Johkura, K Kuchelmeister, K Lury, K Oguz, K Prass, K Rollins, K Wong, KL Newell, L Alderson, L Bataller, M Albert, M Albert, M Geppert, M Ito, M Keegan, M Nishie, MD Norenberg, MN Hart, MS Knaap van der, MS Knaap van der, MS Knaap van der, MS Knaap van der, N Ghatak, N Ghosh, P Jorens, PAJ Leegwater, R Bakshi, R Biancheri, R Friede, R Li, R Okeda, R Rust, RC Dale, RD Adams, RD Adams, S Marangoni, S Schwarz, S Terae, S Vernino, SN Murthy, T Furusawa, T Kuhlmann, T Pandey, Tanja Kuhlmann, TN Shenkier, VA Lennon, W Alexander, W Bruck, W Brück, W Brück, W Brück, W Schlote, Wolfgang Brück, Y Kuroda   +94 more
core   +2 more sources

Neuroimaging for differential diagnosis of transient neurological attacks

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Background Rapid yet comprehensive neuroimaging protocols are required for patients with suspected acute stroke. However, stroke mimics can account for approximately one in five clinically diagnosed acute ischemic strokes and the rate of thrombolyzed mimics can be as high as 17%.
Ying Wang, Hao Zha
wiley   +1 more source

Microglial/macrophage activation in the cerebrospinal fluid of neuromyelitis optica spectrum disorders

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Aim The aims of this pilot study were to investigate the levels of biomarkers of microglial/macrophage activation—YKL‐40, sCD163, and sCD14—in patients with neuromyelitis optica spectrum disorder (NMOSD) and determine the possible associations between these biomarkers and Expanded Disability Status Scale (EDSS) scores.
Jinghong Li, Yan He, Honghao Wang, Jinyu Chen   +3 more
wiley   +1 more source