Results 41 to 50 of about 76,100 (290)
Journal of Clinical Pathology, 2006 A diagnosis of demyelination carries important therapeutic and prognostic implications. In most cases the diagnosis is made clinically, and involvement of the histopathologist is largely confined to postmortem confirmation and clinicopathological correlation.
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Induced CNS expression of CXCL1 augments neurologic disease in a murine model of multiple sclerosis via enhanced neutrophil recruitment. [PDF]
, 2018 Increasing evidence points to an important role for neutrophils in participating in the pathogenesis of the human demyelinating disease MS and the animal model EAE.
Doty, Daniel J +7 more
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Diagnostics, 2023 This study aimed to identify the clinical significance of iron rim lesions (IRLs) in distinguishing multiple sclerosis (MS) from other central nervous system (CNS) demyelinating diseases, determine the relationship between IRLs and disease severity, and ...
Sooyoung Kim +3 more
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Galectin-1 in myelin repair [PDF]
, 2016 Galectin-1 (Gal-1) is a member of a highly conserved family of animal lectins which binds to the common disaccharide [Galβ(1-4)-GlcNAc] on both N- and O-glycans decorating cell surface glycoconjugates.
Pasquini, Laura Andrea +2 more
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Frontiers in Genetics, 2019 Exosomes can pass through the blood-brain barrier and are present in the cerebrospinal fluid (CSF). The components in exosomes, such as DNA, RNA, protein, and lipids, change greatly and are closely related to disease progression.
Jinting He +6 more
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Fulminant Demyelinating Diseases [PDF]
The Neurohospitalist, 2013 Fulminant demyelinating disease is a heading that covers acute disseminated encephalomyelitis and its variant acute hemorrhagic leukoencephalitis (Hurst disease), severe relapses of multiple sclerosis (MS), variants of MS (tumefactive MS, Marburg variant, Balo concentric sclerosis, myelinoclastic diffuse sclerosis), and neuromyelitis optica-spectrum ...
Orhun H. Kantarci, Megan R. Rahmlow
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Anaesthesia and demyelinating disease [PDF]
Anaesthesia, 1980 SummaryThe demyelinating diseases are classified and the current concepts of the aetiology and pathophysiology of the most common of these diseases, multiple sclerosis, are described. The effects of the impaired function, local responses and known complications of the disease on the choice of anaesthetic, drugs and techniques are discussed.
T. E. J. Healy, Ronald M. Jones
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Peripheral Demyelinating Diseases: From Biology to Translational Medicine
Frontiers in Neurology, 2019 Demyelinating diseases represent a spectrum of disorders that impose significant burden on global economy and society. Generally, the prognosis of these diseases is poor and there is no available cure.
Khidhir Kamil +4 more
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Placental Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Myelin Regeneration in an Animal Model of Multiple Sclerosis. [PDF]
, 2019 Mesenchymal stem/stromal cells (MSCs) display potent immunomodulatory and regenerative capabilities through the secretion of bioactive factors, such as proteins, cytokines, chemokines as well as the release of extracellular vesicles (EVs).
Barthe, Sylvain +11 more
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Guillain-Barré syndrome: a century of progress [PDF]
, 2016 In 1916, Guillain, Barré and Strohl reported on two cases of acute flaccid paralysis with high cerebrospinal fluid protein levels and normal cell counts — novel findings that identified the disease we now know as Guillain–Barré syndrome (GBS).
A Campbell +91 more
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