Results 61 to 70 of about 9,399,438 (251)
Diagnostics, 2023 This study aimed to identify the clinical significance of iron rim lesions (IRLs) in distinguishing multiple sclerosis (MS) from other central nervous system (CNS) demyelinating diseases, determine the relationship between IRLs and disease severity, and ...
Sooyoung Kim +3 more
doaj +1 more source
Five Decades of Cuprizone, an Updated Model to Replicate Demyelinating Diseases
Current Neuropharmacology, 2019 Introduction: Demyelinating diseases of the central nervous system (CNS) comprise a group of neurological dis-orders characterized by progressive (and eventually irreversible) loss of oligodendrocytes and myelin sheaths in the white matter tracts.
J. Vega-Riquer +3 more
semanticscholar +1 more source
Demyelinating Diseases of the CNS (Brain and Spine)
IDKD Springer Series, 2020 Multiple sclerosis (MS) is the most important idiopathic inflammatory disorders that affects both the brain and spine. Dissemination in space and time on MRI is not limited to MS and can occur in neuromyelitis optica (NMO) and a series of other ...
F. Barkhof, K. Koeller
semanticscholar +1 more source
Olfactory Pathology in Central Nervous System Demyelinating Diseases
Brain Pathology, 2014 Gabriele C. DeLuca +6 more
openalex +3 more sources
Glia, 2019 Oligodendrocytes (OLs) are the myelinating glia of the central nervous system. Injury to OLs causes myelin loss. In demyelinating diseases, such as multiple sclerosis, the remyelination is hindered principally due to a failure of the oligodendrocyte ...
N. Suo +4 more
semanticscholar +1 more source
Placental Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Myelin Regeneration in an Animal Model of Multiple Sclerosis. [PDF]
, 2019 Mesenchymal stem/stromal cells (MSCs) display potent immunomodulatory and regenerative capabilities through the secretion of bioactive factors, such as proteins, cytokines, chemokines as well as the release of extracellular vesicles (EVs).
Barthe, Sylvain +11 more
core +2 more sources
Frontiers in Genetics, 2019 Exosomes can pass through the blood-brain barrier and are present in the cerebrospinal fluid (CSF). The components in exosomes, such as DNA, RNA, protein, and lipids, change greatly and are closely related to disease progression.
Jinting He +6 more
doaj +1 more source
Galectin-1 in myelin repair [PDF]
, 2016 Galectin-1 (Gal-1) is a member of a highly conserved family of animal lectins which binds to the common disaccharide [Galβ(1-4)-GlcNAc] on both N- and O-glycans decorating cell surface glycoconjugates.
Pasquini, Laura Andrea +2 more
core +2 more sources
The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system. [PDF]
, 1992 Following intracerebral inoculation of adult Balb/c Byj mice, the MHV-4 strain of mouse hepatitis virus (MHV) had an LD50 of less than 0.1 PFU, whereas its monoclonal antibody resistant variant V5A13.1 had an LD50 of 10(4.2) PFU.
Bloom, F +3 more
core +1 more source
Guillain-Barré syndrome: a century of progress [PDF]
, 2016 In 1916, Guillain, Barré and Strohl reported on two cases of acute flaccid paralysis with high cerebrospinal fluid protein levels and normal cell counts — novel findings that identified the disease we now know as Guillain–Barré syndrome (GBS).
A Campbell +91 more
core +1 more source