Results 311 to 320 of about 97,922 (342)
Some of the next articles are maybe not open access.
The Biochemistry of Demyelination and Demyelinating Diseases
1972Wallerian degeneration was the first experimental model of demyelination devised and has been widely investigated both structurally and biochemically. After severing a peripheral nerve there is increasing loss of cerebrosides, sphingomyelin, cholesterol and phospholipids, that of the cephalins starting earlier and exceeding that of lecithin [1]. During
openaire +2 more sources
Tumefactive demyelinating lesions
Neuroradiology, 1996We studied 21 cases of pathologically confirmed tumefactive demyelinating lesions and reviewed the spectrum of tumefactive demyelinating lesions in the literature. Radiological features and clinical data were reviewed to characterize the lesions as consistent with a known demyelinating disease, most notably multiple sclerosis.
A. P. Dagher +2 more
openaire +3 more sources
Superantigens in demyelinating disease
Springer Seminars in Immunopathology, 1996Autoreactive T cells are part of the normal lymphocyte repertoire of healthy individuals [4]. In the immune system of healthy individuals, potent regulatory mechanisms control T and B cell tolerance to self antigens. While genetic factors influence susceptibility to autoimmunity in humans and experimental animals, environmental factors contribute to ...
Stefan Brocke +2 more
openaire +3 more sources
Demyelinating Diseases: Acute Demyelinating Encephalomyelitis (ADEM) [PDF]
, 2019 Acute demyelinating encephalomyelitis (ADEM) is clinically characterized by fever, headache, impaired conscious level, meningism, seizures, and progressive neurological signs.
Michael Sonnberger +6 more
openaire +1 more source
Neurological Research, 2006
White matter lesions representing ischemic demyelination have evolved in terms of our understanding of their pathogenesis and potential clinical significance. Low density lesions on CT brain scan, most commonly seen in the periventricular region, also frequently seen in the centrum semiovale, have been termed 'leukoaraiosis'.
openaire +2 more sources
White matter lesions representing ischemic demyelination have evolved in terms of our understanding of their pathogenesis and potential clinical significance. Low density lesions on CT brain scan, most commonly seen in the periventricular region, also frequently seen in the centrum semiovale, have been termed 'leukoaraiosis'.
openaire +2 more sources
Chronic inflammatory demyelinating polyradiculoneuropathy with tumefactive central demyelination
Muscle & Nerve, 2005AbstractA 46‐year‐old man with a 1‐year history of distal paresthesias and mild distal weakness subacutely developed paralysis of the left hand. Electrodiagnostic evaluation revealed a demyelinating peripheral neuropathy that met criteria for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).
Fred H. Hochberg +2 more
openaire +3 more sources
Autoimmunity in Demyelinating Diseases
Annals of the New York Academy of Sciences, 1987Demyelinative diseases of the CNS and peripheral nervous system can be distinguished on the basis of primary mediation by antibody or T lymphocytes (or failure of the T-cell-mediated response) and on the basis of chronicity. The principal mechanisms are autoimmunization to myelin antigens after actual immunization with tissue or infection with cross ...
openaire +4 more sources
Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
Annals of Neurology, 2000C. Lucchinetti +5 more
semanticscholar +1 more source