Results 51 to 60 of about 388,663 (309)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

DETERMINAÇÃO ESPECTROFOTOMÉTRICA DE WPNI E HMF EM LEITE UHT ATRAVÉS DA ANÁLISE POR COMPONENTES PRINCIPAIS

Química Nova, 2016
During heat treatment milk suffers changes among which whey proteins insolubility and Maillard reaction can be monitored using spectrophotometric methods by determining the whey protein nitrogen (WPNI) and 5-hydroxymethylfurfural (HMF).
Leandra N. O. Neves, Paulo Henrique F. da Silva, Marcone A. L. de Oliveira   +2 more
doaj   +1 more source

Fabrication of Silver Nanoparticles Against Fungal Pathogens

Frontiers in Nanotechnology, 2021
The use of silver nanoparticles (AgNPs) against various pathogens is now being well recognized in the agriculture and health sector. Nanoparticles have been shown to exhibit various novel properties and these properties, on other hand, rely upon the size,
Sheikh Mansoor, Irfana Zahoor, Tawseef Rehman Baba, Shahid A. Padder, Z. A. Bhat, Aabid Mustafa Koul, Linghuo Jiang   +6 more
doaj   +1 more source

Cold Denaturation Unveiled: Molecular Mechanism of the Asymmetric Unfolding of Yeast Frataxin [PDF]

, 2015
What is the mechanism that determines the denaturation of proteins at low temperatures, which is, by now, recognized as a fundamental property of all proteins?
Domenico Sanfelice, Pastore, Annalisa; id_orcid, Temussi Piero Andrea, Piero Andrea Temussi, Sanfelice Domenico, Pastore Annalisa, Annalisa Pastore, Niccolai Neri, Edoardo Morandi, Morandi Edoardo, NICCOLAI, NERI, MORANDI, EDOARDO, Temussi, Piero Andrea, Neri Niccolai, PASTORE, ANNALISA, Sanfelice, Domenico   +15 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Low-Denaturazing Glucose Oxidase Immobilization onto Graphite Electrodes by Incubation in Chitosan Solutions

Polysaccharides, 2022
In this work, glucose oxidase (GOx) has been immobilized onto graphite rod electrodes through an assisted-chitosan adsorption reaching an enzyme coverage of 4 nmol/cm2.
Mireia Buaki-Sogó, Laura García-Carmona, Mayte Gil-Agustí, Marta García-Pellicer, Alfredo Quijano-López   +4 more
doaj   +1 more source

Feasibility of microfluidic routes to monitor protein stability as a tool for bioprocessing [PDF]

, 2010
During the bioprocessing of therapeutics, proteins may become damaged leading to modifications and changes in stability. This may, as a consequence, cause serious and potentially fatal side effects when administered to patients making damage ...
Remtulla, N.
core  

Fluorescence recovery after denaturation of FbFPs.

, 2013
FbFPs were denatured by incubation at 70 or 90°C for 25 minutes. Denaturation at 70°C was accompanied by the progressive loss of peak fluorescence emission at 495 nm.
Kevin B. Weyant (416989), Charles M. Schroeder (416990), Joshua Walker (416988), Arnab Mukherjee (416987)   +3 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

DENATURATION OF NATIVE AND DEGLYCOSYLATED α-GALACTOSIDASES FROM Penicillium canescens BY GUANIDINE HYDROCHLORIDE [PDF]

Biotechnologia Acta, 2015
The aim of this work was the study of native and galactosidases from Penicillium canescens under denaturing conditions caused by guanidine hydrochloride.
Borzova N. V.
doaj   +1 more source