The Effect of Dimethyl Sulfoxide on the Lysozyme Unfolding Kinetics, Thermodynamics, and Mechanism
Biomolecules, 2019 The thermal stability of proteins in the presence of organic solvents and the search for ways to increase this stability are important topics in industrial biocatalysis and protein engineering.
Timur Magsumov +3 more
doaj +1 more source
, 2014 Mean transition midpoints of thermal denaturation (CD spectroscopy, FAD fluorescence, ANS fluorescence).
Johanna M. Jank (549307) +10 more
core +1 more source
Structure and dynamics of unfolded polypeptide chains [PDF]
, 2005 This thesis aimed at improving our knowledge about the dynamic and structural properties of the unfolded states of proteins. Unstructured peptides were used as model systems to probe the structure and the dynamics of such states. Special emphasis was put
Möglich, Andreas
core +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
The dynamics of the DNA denaturation transition
, 2012 The dynamics of the DNA denaturation is studied using the Peyrard-Bishop-Dauxois model. The denaturation rate of double stranded polymers decreases exponentially as a function of length below the denaturation temperature.
Titus S. van Erp, Michel Peyrard
core +1 more source
Second harmonic generation confocal microscopy of collagen type I from rat tendon cryosections [PDF]
, 2006 We performed second harmonic generation (SHG) imaging of collagen in rat-tendon cryosections, using femtosecond laser scanning confocal microscopy, both in backscattering and transmission geometries.
Theodossiou, Theodossis A. +11 more
core +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Free energy and transition midpoint of urea denaturation of native and acetylated TSPs and αA-Cry.
, 2016 Free energy and transition midpoint of urea denaturation of native and acetylated TSPs and αA-Cry.
Reza Yousefi (3125688) +4 more
core +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Numerical Study of the Effect of Freestream Turbulence on by-pass Transition in a Boundary Layer [PDF]
, 2014 We use direct numerical simulations in the presence of free-stream turbulence having different values of intensity, T u, and integral length scale, L, in order to determine which kind of structures are involved in the path to transition of a boundary ...
Robinet, Jean Christophe +3 more
core +1 more source