Results 1 to 10 of about 42,026 (268)

In vitro and in vivo toxicity and histopathological evaluation of Gd(III)anionic Linear globular dendrimer second-generation G2-C595 nanoprobe [PDF]

Nanomedicine Journal, 2020
Objective(s): Toxico-histopathological studies are used to assess the toxic impacts of nanoparticles in organism exposure. The present study aimed to evaluate the prospective nano-cytotoxicity impacts of Gd(III)-anionic linear globular dendrimer second ...
Mehdi Mirzaei, Mohammad Esmaeil Akbari, Mohammad Ali Mohagheghi, Seyed Mohammad Tavangar, Bita Mehravi, Mehdi Shafiee Ardestani   +5 more
doaj   +1 more source

Rapid Bacterial Recognition over a Wide pH Range by Boronic Acid-Based Ditopic Dendrimer Probes for Gram-Positive Bacteria

Molecules, 2021
We have developed a convenient and selective method for the detection of Gram-positive bacteria using a ditopic poly(amidoamine) (PAMAM) dendrimer probe.
Ayame Mikagi, Koichi Manita, Asuka Yoyasu, Yuji Tsuchido, Nobuyuki Kanzawa, Takeshi Hashimoto, Takashi Hayashita   +6 more
doaj   +1 more source

The Role of Branch Cell Symmetry and Other Critical Nanoscale Design Parameters in the Determination of Dendrimer Encapsulation Properties

Biomolecules, 2020
This article reviews progress over the past three decades related to the role of dendrimer-based, branch cell symmetry in the development of advanced drug delivery systems, aqueous based compatibilizers/solubilizers/excipients and nano-metal cluster ...
Donald A. Tomalia, Linda S. Nixon, David M. Hedstrand   +2 more
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COMPUTER MODELING OF INTERACTION OF LYSINE DENDRIMER WITH EPITHALON PEPTIDES [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2018
Subject of Study.Dendrimers are hyperbranched polymeric molecules that regularly branch from a single center. Dendrimers are used in biomedical applications to deliver drugs and genetic material to cells.
D. N. Khamidova, �. V. Popovа, V. V. Bezrodny, S. E. Mikhtanyuk, E. V. Popova, I. M. Neelov, F. Leermakers   +6 more
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Size and Structure of Empty and Filled Nanocontainer Based on Peptide Dendrimer with Histidine Spacers at Different pH

Molecules, 2021
Novel peptide dendrimer with Lys-2His repeating units was recently synthesized, studied by NMR (Molecules, 2019, 24, 2481) and tested as a nanocontainer for siRNA delivery (Int. J. Mol. Sci., 2020, 21, 3138).
Valeriy V. Bezrodnyi, Sofia E. Mikhtaniuk, Oleg V. Shavykin, Igor M. Neelov, Nadezhda N. Sheveleva, Denis A. Markelov   +5 more
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Helical micelle of an achiral surfactant from the template interaction with dendrimer

Giant, 2023
The electrostatic interaction between of poly(amidoamine) (PAMAM) G9 dendrimer and an achiral surfactant, dodecylbenzenesulfonic acid (DBSA), leads to the formation of nucleosome-like structure, where the globular dendrimer molecule directs the DBSA ...
Yi-Cheng Lai, Bradley W. Mansel, Chun-Yu Chen, Chih-Ying Liu, Yu-Hsiang Chen, Chun-Jen Su, U-Ser Jeng, Hsin-Lung Chen   +7 more
doaj   +1 more source

Dendrimer-based drug delivery systems: history, challenges, and latest developments

Journal of Biological Engineering, 2022
Since the first dendrimer was reported in 1978 by Fritz Vögtle, dendrimer research has grown exponentially, from synthesis to application in the past four decades.
Juan Wang, Boxuan Li, Li Qiu, Xin Qiao, Hu Yang   +4 more
doaj   +1 more source

Synergistic cellular toxicity and uptake effects of iodixanol conjugated to anionic linear globular dendrimer G2 [PDF]

Nanomedicine Journal, 2020
Objective(s): Early diagnosis of cancer using noninvasive imaging techniques has been discussed in several recent studies. The present study aimed to assess the synergistic effects of iodixanol-conjugated polyethylene glycol (PEG)-citrate (anionic linear
Mitra Kiani, Paria Mojarrad, Mehdi Shafiee Ardestani   +2 more
doaj   +1 more source

Partially glycosylated dendrimers block MD-2 and prevent TLR4-MD-2-LPS complex mediated cytokine responses. [PDF]

PLoS Computational Biology, 2011
The crystal structure of the TLR4-MD-2-LPS complex responsible for triggering powerful pro-inflammatory cytokine responses has recently become available. Central to cell surface complex formation is binding of lipopolysaccharide (LPS) to soluble MD-2. We
Teresa S Barata, Ian Teo, Steve Brocchini, Mire Zloh, Sunil Shaunak   +4 more
doaj   +1 more source

Review Dendrimer : Definisi, Sintesis, Aplikasi Dan Prospektif

Jurnal Kimia dan Kemasan, 2013
Dendrimer merupakan makrostruktur monodisperse dengan banyak cabang yang homogen dan degree of branching (DB) 100%. Dua cara sintesis dendrimer yaitu convergent dan divergent dilakukan.
Dwinna Rahmi
doaj   +1 more source