Results 1 to 10 of about 85,577 (346)

Dendrimer-based drug delivery systems: history, challenges, and latest developments

Journal of Biological Engineering, 2022
Since the first dendrimer was reported in 1978 by Fritz Vögtle, dendrimer research has grown exponentially, from synthesis to application in the past four decades.
Juan Wang, Boxuan Li, Li Qiu, Xin Qiao, Hu Yang   +4 more
doaj   +2 more sources

A boronic acid–rich dendrimer with robust and unprecedented efficiency for cytosolic protein delivery and CRISPR-Cas9 gene editing

Science Advances, 2019
We report the rational design of a polymer with unprecedented and robust efficiency for cytosolic delivery of native proteins. Cytosolic protein delivery is of central importance for the development of protein-based biotechnologies and therapeutics ...
Chongyi Liu, Tao Wan, Song Zhang
exaly   +2 more sources

Development of a Topical Resveratrol Formulation for Commercial Applications Using Dendrimer Nanotechnology

Molecules, 2017
Resveratrol (RSV) is well known for its anti-oxidant and anti-aging properties. However, resveratrol is insoluble in water and has stability issues. Recently, efforts were placed to prepare a resveratrol-based advanced anti-aging topical product but it ...
Tyler Pentek, Eric Newenhouse, Brennin O’Brien, Abhay Singh Chauhan   +3 more
doaj   +2 more sources

Photodynamic Microbial Defense of Cotton Fabric with 4-Amino-1,8-naphthalimide-Labeled PAMAM Dendrimer. [PDF]

Materials (Basel)
Staneva D, Atanasova D, Grabchev I.
europepmc   +3 more sources

Dendrimer-Encapsulated Metal Nanoparticles:  Synthesis, Characterization, and Applications to Catalysis

Accounts of Chemical Research, 2001
Richard M Crooks
exaly   +2 more sources

In vitro and in vivo toxicity and histopathological evaluation of Gd(III)anionic Linear globular dendrimer second-generation G2-C595 nanoprobe [PDF]

Nanomedicine Journal, 2020
Objective(s): Toxico-histopathological studies are used to assess the toxic impacts of nanoparticles in organism exposure. The present study aimed to evaluate the prospective nano-cytotoxicity impacts of Gd(III)-anionic linear globular dendrimer second ...
Mehdi Mirzaei, Mohammad Esmaeil Akbari, Mohammad Ali Mohagheghi, Seyed Mohammad Tavangar, Bita Mehravi, Mehdi Shafiee Ardestani   +5 more
doaj   +1 more source

Rapid Bacterial Recognition over a Wide pH Range by Boronic Acid-Based Ditopic Dendrimer Probes for Gram-Positive Bacteria

Molecules, 2021
We have developed a convenient and selective method for the detection of Gram-positive bacteria using a ditopic poly(amidoamine) (PAMAM) dendrimer probe.
Ayame Mikagi, Koichi Manita, Asuka Yoyasu, Yuji Tsuchido, Nobuyuki Kanzawa, Takeshi Hashimoto, Takashi Hayashita   +6 more
doaj   +1 more source

A fluorinated dendrimer achieves excellent gene transfection efficacy at extremely low nitrogen to phosphorus ratios

Nature Communications, 2014
Yiyun Cheng
exaly   +2 more sources

The Role of Branch Cell Symmetry and Other Critical Nanoscale Design Parameters in the Determination of Dendrimer Encapsulation Properties

Biomolecules, 2020
This article reviews progress over the past three decades related to the role of dendrimer-based, branch cell symmetry in the development of advanced drug delivery systems, aqueous based compatibilizers/solubilizers/excipients and nano-metal cluster ...
Donald A. Tomalia, Linda S. Nixon, David M. Hedstrand   +2 more
doaj   +1 more source

Size and Structure of Empty and Filled Nanocontainer Based on Peptide Dendrimer with Histidine Spacers at Different pH

Molecules, 2021
Novel peptide dendrimer with Lys-2His repeating units was recently synthesized, studied by NMR (Molecules, 2019, 24, 2481) and tested as a nanocontainer for siRNA delivery (Int. J. Mol. Sci., 2020, 21, 3138).
Valeriy V. Bezrodnyi, Sofia E. Mikhtaniuk, Oleg V. Shavykin, Igor M. Neelov, Nadezhda N. Sheveleva, Denis A. Markelov   +5 more
doaj   +1 more source