Results 91 to 100 of about 54,440 (362)

Brain Targeting of a Water Insoluble Antipsychotic Drug Haloperidol via the Intranasal Route Using PAMAM Dendrimer.

open access: yesMolecular Pharmaceutics, 2015
Delivery of therapeutics to the brain is challenging because many organic molecules have inadequate aqueous solubility and limited bioavailability.
Y. Katare   +6 more
semanticscholar   +1 more source

Wood and Cellulose: the Most Sustainable Advanced Materials for Past, Present, and Future Civilizations

open access: yesAdvanced Materials, EarlyView.
Wood and cellulose are the most abundant and important sustainable materials on the planet at the disposal to solve major societal challenges. This perspective, written for all materials scientists, highlights how breakthroughs in cellulose nanotechnology combined with functional nanomaterials can revolutionize important areas like construction ...
Mahiar Max Hamedi   +5 more
wiley   +1 more source

Antigen targeting to dendritic cells: Still a place in future immunotherapy?

open access: yesEuropean Journal of Immunology, Volume 52, Issue 12, Page 1909-1924, December 2022., 2022
Dendritic cell‐based immunotherapy is a promising vaccination strategy to treat infectious diseases, autoimmunity, and cancer. In this review, we present an overview on the current state of antigen targeting approaches via C‐type lectin receptors, with an outlook on future developments and potential for clinical translation.
Patrizia Stoitzner   +4 more
wiley   +1 more source

The key role of the scaffold on the efficiency of dendrimer nanodrugs

open access: yesNature Communications, 2015
Dendrimers are well-defined macromolecules whose highly branched structure is reminiscent of many natural structures, such as trees, dendritic cells, neurons or the networks of kidneys and lungs.
A. Caminade   +12 more
semanticscholar   +1 more source

Unlocking Multimodal Nonlinear Microscopy for Deep‐Tissue Imaging under Continuous‐Wave Excitation with Tunable Upconverting Nanoparticles

open access: yesAdvanced Materials, EarlyView.
This study introduces a multimodal nonlinear microscopy approach using upconverting nanoparticles (UCNPs) under continuous‐wave excitation. The UCNPs exhibit high‐order nonlinear optical responses, enabling deep‐tissue 3D imaging, video‐rate wide‐field imaging, and depth‐selective photomodulation.
Jeongmo Kim   +13 more
wiley   +1 more source

Novel Approaches To Design Glycan‐Based Antibacterial Inhibitors

open access: yesEuropean Journal of Organic Chemistry, Volume 26, Issue 1, January 2, 2023., 2023
Sweet and sticky: This review describes recent advances in the synthesis and application of homo‐and heterovalent glycan‐scaffolds as potential candidates for efficient bacteria lectin inhibition. To study and address the many complex molecular mechanisms involved in multivalent lectin binding events, novel glycoconjugate designs and fine‐tunable ...
Sandra Behren, Ulrika Westerlind
wiley   +1 more source

DNA Condensation by Partially Acetylated Poly(amido amine) Dendrimers: Effects of Dendrimer Charge Density on Complex Formation

open access: yesMolecules, 2013
The ability of poly(amido amine) (or PAMAM) dendrimers to condense semiflexible dsDNA and penetrate cell membranes gives them great potential in gene therapy and drug delivery but their high positive surface charge makes them cytotoxic. Here, we describe
Ronald G. Larson   +4 more
doaj   +1 more source

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

open access: yesAdvanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin   +8 more
wiley   +1 more source

Optical Nanoscopy for Elucidating Nano–Bio Interactions: A One Health Perspective

open access: yesAdvanced Optical Materials, EarlyView.
The review comprehensively summarizes the application of far‐field fluorescence nanoscopy for the characterization of nanomaterial interactions with biological systems at the single‐particle and molecular scale, with an accent on their impact on human and ecosystem health.
Elisa De Luca   +5 more
wiley   +1 more source

Electrode‐supported and free‐standing bilayer lipid membranes: Formation and uses in molecular electrochemistry

open access: yesElectrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022
Abstract This short review is aimed at emphasizing the recent most prominent advances in the electrochemical investigation of the interactions of molecules with purely lipid bilayers. The first part which deals with electrode‐supported bilayer lipid membranes is articulated around the nature of electrode material with a focus on mercury to celebrate ...
Eric Labbé, Olivier Buriez
wiley   +1 more source

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