Results 31 to 40 of about 85,577 (346)

Condensation transition in DNA-polyaminoamide dendrimer fibers studied using optical tweezers [PDF]

, 2006
When mixed together, DNA and polyaminoamide (PAMAM) dendrimers form fibers that condense into a compact structure. We use optical tweezers to pull condensed fibers and investigate the decondensation transition by measuring force-extension curves (FECs ...
C. Bustamante, C. G. Baumann, F. Ritort, G. I. Bell, J. F. Marko, S. B. Smith, S. Mihardja   +6 more
core   +2 more sources

Effect of Terminal Groups of Dendrimers in the Complexation with Antisense Oligonucleotides and Cell Uptake [PDF]

, 2016
Indexación: Web of Science.Poly(amidoamine) dendrimers are the most recognized class of dendrimer. Amino-terminated (PAMAM-NH2) and hydroxyl-terminated (PAMAM-OH) dendrimers of generation 4 are widely used, since they are commercially available.
Araya-Durán, Ingrid, Céric, Francisco, Fuentes, Juan, González-Nilo, Fernando D., Márquez-Miranda, Valeria, Otero, Carolina, Peñaloza, Juan Pablo, Reyes, Rodrigo, Romero, Valentina, Velásquez, Luis, Vidaurre, Soledad   +10 more
core   +1 more source

Dendrimer‐Stabilized Gold Nanoflowers Embedded with Ultrasmall Iron Oxide Nanoparticles for Multimode Imaging–Guided Combination Therapy of Tumors

Advancement of science, 2018
Development of multifunctional theranostic nanoplatforms with improved diagnostic sensitivity and therapeutic efficiency of tumors still remains a great challenge.
Shiying Lu, Xin Li, Jiulong Zhang, C. Peng, Mingwu Shen, Xiangyang Shi   +5 more
semanticscholar   +1 more source

Pharmacokinetics of Chiral Dendrimer-Triamine-Coordinated Gd-MRI Contrast Agents Evaluated by in Vivo MRI and Estimated by in Vitro QCM

Sensors, 2015
Recently, we developed novel chiral dendrimer-triamine-coordinated Gd-MRI contrast agents (Gd-MRI CAs), which showed longitudinal relaxivity (r1) values about four times higher than that of clinically used Gd-DTPA (Magnevist®, Bayer).
Yuka Miyake, Syungo Ishikawa, Yu Kimura, Aoi Son, Hirohiko Imai, Tetsuya Matsuda, Hisatsugu Yamada, Akio Toshimitsu, Teruyuki Kondo   +8 more
doaj   +1 more source

Self-assembling supramolecular dendrimer nanosystem for PET imaging of tumors

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Nanotechnology-based imaging is expected to bring breakthroughs in cancer diagnosis by improving imaging sensitivity and specificity while reducing toxicity.
P. Garrigue, Jingjie Tang, Ling Ding, Ahlem Bouhlel, Aura Tintaru, E. Laurini, Yuanyu Huang, Zhenbin Lyu, Mengjie Zhang, Samantha Fernandez, L. Balasse, Wenjun Lan, E. Mas, D. Marson, Yuhua Weng, Xiaoxuan Liu, S. Giorgio, J. Iovanna, S. Pricl, B. Guillet, Ling Peng   +20 more
semanticscholar   +1 more source

Bolstering cholesteryl ester hydrolysis in liver: A hepatocyte-targeting gene delivery strategy for potential alleviation of atherosclerosis [PDF]

, 2017
Current atherosclerosis treatment strategies primarily focus on limiting further cholesteryl esters (CE) accumulation by reducing endogenous synthesis of cholesterol in the liver.
Ghosh, Shobha, He, Hongliang, Korzun, William J., Lancina, Michael G., III, Wang, Jing, Yang, Hu   +5 more
core   +2 more sources

Correction: Tomalia, D.A. Dendrimers, Dendrons, and the Dendritic State: Reflection on the Last Decade with Expected New Roles in Pharma, Medicine, and the Life Sciences. Pharmaceutics 2024, 16, 1530

Pharmaceutics
In the original publication [...]
Donald A. Tomalia
doaj   +1 more source

Dendrimers in Layer-by-Layer Assemblies: Synthesis and Applications

Molecules, 2013
We review the synthesis of dendrimer-containing layer-by-layer (LbL) assemblies and their applications, including biosensing, controlled drug release, and bio-imaging.
Katsuhiko Sato, Jun-ichi Anzai
doaj   +1 more source

Erlotinib-Loaded Dendrimer Nanocomposites as a Targeted Lung Cancer Chemotherapy

Molecules, 2023
Lung cancer is the main cause of cancer-related mortality globally. Erlotinib is a tyrosine kinase inhibitor, affecting both cancerous cell proliferation and survival.
Wafa K. Fatani, Fadilah S. Aleanizy, Fulwah Y. Alqahtani, Mohammed M. Alanazi, Abdullah A. Aldossari, Faiyaz Shakeel, Nazrul Haq, Hosam Abdelhady, Hamad M. Alkahtani, Ibrahim A. Alsarra   +9 more
doaj   +1 more source

Synthesis, Internalization and Visualization of N-(4-Carbomethoxy) Pyrrolidone Terminated PAMAM [G5:G3-TREN] Tecto(dendrimers) in Mammalian Cells

Molecules, 2020
Tecto(dendrimers) are well-defined, dendrimer cluster type covalent structures. In this article, we present the synthesis of such a PAMAM [G5:G3-(TREN)]-N-(4-carbomethoxy) pyrrolidone terminated tecto(dendrimer).
Maciej Studzian, Paula Działak, Łukasz Pułaski, David M. Hedstrand, Donald A. Tomalia, Barbara Klajnert-Maculewicz   +5 more
doaj   +1 more source