Results 101 to 110 of about 54,619 (251)

Origin of broad polydispersion in functionalized dendrimers and its effects on cancer cell binding affinity

open access: yes, 2010
Nanoparticles with multiple ligands have been proposed for use in nanomedicine. The multiple targeting ligands on each nanoparticle can bind to several locations on a cell surface facilitating both drug targeting and uptake.
Bradford G. Orr   +7 more
core   +1 more source

Practical computational toolkits for dendrimers and dendrons structure design [PDF]

open access: yes, 2017
Dendrimers and dendrons offer an excellent platform for developing novel drug delivery systems and medicines. The rational design and further development of these repetitively branched systems are restricted by difficulties in scalable synthesis and ...
A Kwok   +52 more
core   +3 more sources

A dendrimer enhanced CRISPR/Cas12a performance for the evaluation of acidogenic capacity in cariogenic bacteria

open access: yesInterdisciplinary Medicine, EarlyView.
A CRISPR/Cas12a‐powered dendritic DNA nanostructure is assembled to create confined enzymatic microdomains, enabling ultrasensitive detection. Integrated into a paper‐based origami biosensor, it allows equipment‐free on‐site quantification of acidogenic pathogens for the early diagnosis of dental caries.
Yuan Zhang   +4 more
wiley   +1 more source

Bio‐Inspired, Zwitterionic Copolymers with Amphiphilic Character

open access: yesMacromolecular Rapid Communications, EarlyView.
Zwitterionic copolymers based on arginine‐derived monomers are produced by xanthate‐supported photo‐iniferter reversible‐addition‐fragmentation chain‐transfer polymerization. Experiments in relevant conditions show that the designed (co)polymers hardly interact with biologically relevant proteins and enzymes such as bovine serum albumine (BSA), fetal ...
Theresa M. Lutz   +4 more
wiley   +1 more source

Comparison of MRI properties between multimeric DOTAGA and DO3A gadolinium-dendron conjugates [PDF]

open access: yes, 2019
The inherent lack of sensitivity of MRI needs the development of new Gd contrast agents in order to extend 20Hz,37%, the application of this technique to cellular imaging.
Boutry, Sébastien   +13 more
core   +4 more sources

Glyco‐Nanogels for Modulating Pseudomonas aeruginosa Biofilm

open access: yesMacromolecular Rapid Communications, EarlyView.
Nanogels presenting α‐galactose and β‐fucose can significantly alter Pseudomonas aeruginosa biofilm dynamics through their interaction with lectins. Application timing is crucial: pre‐treatment reduces biofilm, while treatment after biofilm initiation increases biomass.
Sophia Rosencrantz   +4 more
wiley   +1 more source

Patchy Amphiphilic Dendrimers Bind Adenovirus and Control Its Host Interactions and in Vivo Distribution

open access: yes, 2019
The surface of proteins is heterogeneous with sophisticated but precise hydrophobic and hydrophilic patches, which is essential for their diverse biological functions.
Andreozzi, P.   +17 more
core   +1 more source

Electronic coupling mechanisms and characteristics for optically nonlinear photoactive nanomaterials [PDF]

open access: yes, 2004
In a range of nanophotonic energy harvesting materials, resonance energy transfer (RET) is the mechanism for the intermolecular and intramolecular transfer of electronic excitation following the absorption of ultraviolet/visible radiation.
Andrews, David, Bradshaw, D.S.
core   +1 more source

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

open access: yesMacromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

Molecular modelling of dendrimers for nanoscale applications [PDF]

open access: yes, 2000
Dendrimers are well defined, highly branched macromolecules that radiate from a central core and are synthesized through a stepwise, repetitive reaction sequence that guarantees complete shells for each generation, leading to polymers that are ...
Breen, Nicholas   +4 more
core  

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