Results 151 to 160 of about 31,221 (269)

Comparative toxicological assessment of PAMAM and thiophosphoryl dendrimers using embryonic zebrafish

open access: yesInternational Journal of Nanomedicine, 2014
Joseph B Pryor,1 Bryan J Harper,1 Stacey L Harper1,21Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA; 2School of Chemical, Biological, and Environmental Engineering, Oregon State University, Corvallis, OR,
Pryor JB, Harper BJ, Harper SL
doaj  

Lactate metabolism and lactylation in female reproductive diseases: From metabolic rewiring to biomarkers and translational therapeutics

open access: yesClinical and Translational Medicine, Volume 16, Issue 6, June 2026.
1. Lactate‐derived histone lactylation links glycolytic reprogramming to epigenetic regulation in female reproductive diseases. 2. In endometriosis, lactylation may promote inflammatory remodelling, immune dysregulation and ferroptosis resistance. 3. In PCOS, lactylation connects metabolic disturbance to granulosa‐cell dysfunction and hyperandrogenism.
Jiajun Qiao   +5 more
wiley   +1 more source

Multifaceted Role of Extracellular Vesicles: Intercellular Messengers to Therapeutic Applications: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Extracellular vesicles (EVs) are nanoscale carriers, including exosomes, microvesicles, and apoptotic bodies, that mediate intercellular communication by transporting proteins, nucleic acids, lipids, and metabolites. They regulate immunity, tissue repair, and cell differentiation.
Kajal Kamra   +7 more
wiley   +1 more source

Dual‐Responsive Chitosan‐Grafted PNIPAAm Hydrogel Eye Drop Incorporating Insulin‐Imprinted Microgels for Dry Eye Syndrome Treatment

open access: yesMacromolecular Bioscience, Volume 26, Issue 6, June 2026.
ABSTRACT Dry eye syndrome (DES) happens as a result of inadequate tear secretion or excessive evaporation, which leads to ocular surface irritation and damage. A major therapeutic challenge is maintaining effective drug concentrations, as topical formulations are rapidly cleared by blinking and tear turnover.
Masoumeh Alsadat Hosseini   +6 more
wiley   +1 more source

Synthesis of Hyperbranched Polyphenylenes With Controlled Molecular Weight by Suzuki–Miyaura Catalyst‐Transfer Polycondensation

open access: yesMacromolecular Chemistry and Physics, Volume 227, Issue 11, 16 June 2026.
Hyperbranched polyphenylenes with controlled molecular weight and molecular weight distribution are synthesized via Suzuki–Miyaura catalyst‐transfer polycondensation using 3,5‐dibromophenylboronic acid as the monomer and 4‐bromobenzonitrile as the initiator. The molecular weight can be effectively regulated through the initiator‐to‐AB2 monomer ratio up
Mitsutoshi Jikei   +2 more
wiley   +1 more source

PAMAM dendrimers as efficient drug nanocarriers of natural compounds in breast cancer therapeutics. [PDF]

open access: yesFront Oncol
Gulfishan S   +7 more
europepmc   +1 more source

Innovative Drug Delivery Systems for the Treatment of Glaucoma

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu   +9 more
wiley   +1 more source

Investigating the cytotoxic effect of polyethyleneimine nanodendrimer on fibroblast cells. [PDF]

open access: yesInt J Physiol Pathophysiol Pharmacol
Nazeri S   +7 more
europepmc   +1 more source

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