Results 141 to 150 of about 54,619 (251)

Enzyme‐Assisted Synthesis and In Vitro Characterization of Bifunctional PCSK9 Inhibitors

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an important therapeutic target for lowering cholesterol. Here, we report the assembly of a bifunctional molecule combining a PCSK9‐binding peptide with an asialoglycoprotein receptor (ASGPR) ligand.
Yuhui Zhang, Li Wang, Leo Corcilius, Amal K. Reji, Richard J. Payne, Bin Hong, Thomas Durek, Conan K. Wang, David J. Craik   +8 more
wiley   +1 more source

From Mechanisms to Materials: Oximate Reactivity and Emerging Strategies for Organophosphate Detoxification

ChemPhysChem, Volume 27, Issue 7, 14 April 2026.
The development of effective strategies for the detoxification of organophosphorus (OP) nerve agents has evolved from the early mechanistic studies of François Terrier and collaborators, who first elucidated the exceptional nucleophilicity of α‐effect species such as oximes and hydroxamates, to the modern design of supramolecular and material‐based ...
Pedro Rodríguez‐Dafonte
wiley   +1 more source

Comparative toxicological assessment of PAMAM and thiophosphoryl dendrimers using embryonic zebrafish

International Journal of Nanomedicine, 2014
Joseph B Pryor,1 Bryan J Harper,1 Stacey L Harper1,21Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA; 2School of Chemical, Biological, and Environmental Engineering, Oregon State University, Corvallis, OR,
Pryor JB, Harper BJ, Harper SL
doaj  

A density-functional theory investigation of cluster formation in an effective-potential model of dendrimers

, 2014
We consider a system of particles interacting via a purely repulsive, soft-core potential recently introduced to model effective pair interactions between dendrimers, which is expected to lead to the formation of crystals with multiple occupancy of the ...
Pini, Davide
core  

A novel computational study of reverse degree topological indices and entropies for nanostar dendrimers. [PDF]

Sci Rep
Qummer AA, Saqib M, Ali S, Ashebo MA, Jumaniyazov S.   +4 more
europepmc   +1 more source

Carbosilane Dendrimers

, 2009
Roovers, Jacques, Ding, Jianfu
openaire   +2 more sources

The Current State of the Art in PAMAM and PLL Dendrimers, Boron Clusters, and Their Complexes for Biomedical Use. [PDF]

Biomedicines
Kołodziejczyk AM, Błaszczyk E, Karwowski BT.   +2 more
europepmc   +1 more source

Non-Invasive Brain Delivery of G4 70/30 PAMAM Dendrimers via the Intranasal Route. [PDF]

ACS Chem Neurosci
Allahyarzadeh Khiabani N, Elmhirst AR, Dubey O, Poudel A, Singh M, Monville H, Sahouri A, Alani Y, Swanson D, Dunbar GL, Rossignol J.   +10 more
europepmc   +1 more source

The antibacterial effectiveness of fourth-generation poly-amidoamine dendrimers-loaded with amoxicillin in combating methicillin-resistant Staphylococcus aureus. [PDF]

Sci Rep
Alenazi N, Alhabardi SA, Binsuwaidan R, Almutairi JA, Alsunbul M, Alanazi SS, Shakeel F.   +6 more
europepmc   +1 more source

Flipper dendrimers. [PDF]

Chem Sci
Gonzalez-Sanchis N, Bayard F, García-Arcos JM, Mandal T, Roux A, Sakai N, Matile S.   +6 more
europepmc   +1 more source