Results 21 to 30 of about 72,289 (292)

T Cell-Association of Carboxy-Terminal Dendrimers with Different Bound Numbers of Phenylalanine and Their Application to Drug Delivery

Pharmaceutics, 2023
T cells play important roles in various immune reactions, and their activation is necessary for cancer immunotherapy. Previously, we showed that polyamidoamine (PAMAM) dendrimers modified with 1,2-cyclohexanedicarboxylic acid (CHex) and phenylalanine ...
Hiroya Shiba, Tomoka Hirose, Yunshen Fu, Masataka Michigami, Ikuo Fujii, Ikuhiko Nakase, Akikazu Matsumoto, Chie Kojima   +7 more
doaj   +1 more source

Original Multivalent Gold (III) and Dual Gold(III)-Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents [PDF]

, 2017
Original metallophosphorus dendrimers (generation 3, 48 terminal groups) have been prepared via the complexation of phosphorus dendrimers bearing imino-pyridino end groups with Au(III) or with both Au(III) and Cu(II).
Serge M. Mignani, Nabil El Brahmi, Saïd El Kazzouli, Regis Laurent, Sonia Ladeira, Anne-Marie Caminade, Elzbieta Pedziwiatr-Werbicka, Eligia M. Szewcyk, Maria Bryszewska, Mosto M. Bousmina, Thierry Cresteil, Jean Pierre Majoral   +11 more
core   +2 more sources

PAMAM-Calix-Dendrimers: Second Generation Synthesis, Fluorescent Properties and Catecholamines Binding

Pharmaceutics, 2022
A convenient method for the synthesis of the second generation of PAMAM dendrimers based on a p-tert-butylthiacalix[4]arene core in cone, partial cone and 1,3-alternate conformations was developed.
Olga Mostovaya, Igor Shiabiev, Dmitry Pysin, Alesia Stanavaya, Viktar Abashkin, Dzmitry Shcharbin, Pavel Padnya, Ivan Stoikov   +7 more
doaj   +1 more source

Cytotoxicity of Dendrimers [PDF]

Biomolecules, 2019
Drug delivery systems are molecular platforms in which an active compound is packed into or loaded on a biocompatible nanoparticle. Such a solution improves the activity of the applied drug or decreases its side effects. Dendrimers are promising molecular platforms for drug delivery due to their unique properties.
Anna Janaszewska, Joanna Lazniewska, Przemysław Trzepiński, Monika Marcinkowska, Barbara Klajnert-Maculewicz   +4 more
openaire   +4 more sources

Polyamidoamine (PAMAM) dendrimers synthesis, characterization and adsorptive removal of nickel ions from aqueous solution

Journal of Materials Research and Technology, 2020
Nickel is a toxic metal and present in the effluents of electroplating industries. Conventional methods to remove nickel are expensive and ineffective. Heavy metals can be easily adsorbed by dendrimers.
Isra Sohail, Ijaz Ahmad Bhatti, Ambreen Ashar, Fazli Malik Sarim, Muhammad Mohsin, Rizwana Naveed, Muhammad Yasir, Munawar Iqbal, Arif Nazir   +8 more
doaj   +1 more source

Click Chemistry of Melamine Dendrimers: Comparison of “Click-and-Grow” and “Grow-Then-Click” Strategies Using a Divergent Route to Diversity

Molecules, 2022
Dendrimers are attractive macromolecules for a broad range of applications owing to their well-defined shapes and dimensions, highly branched and globular architectures, and opportunities for exploiting multivalency.
Sanami Numai, Risako Yoto, Masataka Kimura, Eric E. Simanek, Yoshikazu Kitano   +4 more
doaj   +1 more source

Molecular modeling to study dendrimers for biomedical applications [PDF]

, 2014
© 2014 by the authors; licensee MDPI; Basel; Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
Buhleier, Carbone, Florida, Helena Florindo, Hess, Klajnert, Liana Silva, Mire Zloh, Nuno Martinho, Radhika, Shaunak, Shcharbin, Steve Brocchini, Teresa Barata, Tomalia, Šebestík   +15 more
core   +4 more sources

Which Dendrimer to Attain the Desired Properties? Focus on Phosphorhydrazone Dendrimers

Molecules, 2018
Among the six Critical Nanoscale Design Parameters (CNDPs) proposed by Prof. Donald A. Tomalia, this review illustrates the influence of the sixth one, which concerns the elemental composition, on the properties of dendrimers.
Anne-Marie Caminade, Jean-Pierre Majoral
doaj   +1 more source

Soft Interaction Between Dissolved Dendrimers: Theory and Experiment [PDF]

, 2000
Using small-angle neutron scattering and liquid integral equation theory, we relate the structure factor of flexible dendrimers of 4th generation to their average shape.
Ballauff, Boris D., Daoud M., de Gennes P. G., Feigin L. A., Fischer M., Flory P. J., Graf H., Hansen J.-P., Hansen J.-P., Higgins J. S., Jusufi A., Lescanec R. L., Likos C. N., Likos C. N., Louis A. A., Louis A. A., Lue L., Löwen H., Mansfield M. L., Micali N., Murat M., Pötschke D., Pötschke D., Ramzi A., Stellbrink J., Topp A., Topp A., von Ferber C., Watzlawek M., Watzlawek M., Welch P., Witten T. A.   +32 more
core   +2 more sources

Analysis of Biotinylated Generation 4 Poly(amidoamine) (PAMAM) Dendrimer Distribution in the Rat Brain and Toxicity in a Cellular Model of the Blood-Brain Barrier

Molecules, 2013
Dendrimers are highly customizable nanopolymers with qualities that make them ideal for drug delivery. The high binding affinity of biotin/avidin provides a useful approach to fluorescently label synthesized dendrimer-conjugates in cells and tissues.
Heather A. Bullen, Kristi L. Haik, Celeste Morris, Steven Wall, Anthony Haskamp, Megan Caroway, Michael Hester, Robert Spaulding, Brett Rossow, Ruth Hemmer, Andrew Hall   +10 more
doaj   +1 more source