Results 81 to 90 of about 43,848 (310)
Inorganic Nanomaterials Meet the Immune System: An Intricate Balance
Advanced Healthcare Materials, EarlyView.Metal nanomaterials influence the immune responses, such as cytokine production and T‐cell activity. Unintended immune modulation can have significant consequences while its fine‐tuning may transform the oncology care. Within this review, a critical analysis is offered regarding the nano/immune‐interaction and suggests the future research directions to
Gloria Pizzoli +3 more
wiley +1 more source
Structure factor and thermodynamics of rigid dendrimers in solution [PDF]
, 2007 The ''polymer reference interaction site model'' (PRISM) integral equation theory is used to determine the structure factor of rigid dendrimers in solution. The theory is quite successful in reproducing experimental structure factors for various dendrimer concentrations. In addition, the structure factor at vanishing scattering vector is calculated via
arxiv +1 more source
Nature of the Effective Interaction Between Dendrimers [PDF]
J. Chem. Phys. 141, 144901 (2014);, 2014 We have performed fully atomistic classical molecular dynamics (MD) simulations to calculate the effective interaction between two polyamidoamine (PAMAM) dendrimers. Using the umbrella sampling (US) technique, we have obtained the potential of mean force (PMF) between the dendrimers and investigated the effects of protonation level and dendrimer size ...
arxiv +1 more source
Dendrimers Show Promise for siRNA and microRNA Therapeutics
Pharmaceutics, 2018 The lack of an appropriate intracellular delivery system for therapeutic nucleic acids (TNAs) is a major problem in molecular biology, biotechnology, and medicine.
V. Dzmitruk +5 more
semanticscholar +1 more source
Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
Advanced Healthcare Materials, EarlyView.In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim +11 more
wiley +1 more source
Novel Aldehyde-Terminated Dendrimers; Synthesis and Cytotoxicity Assay
BioImpacts, 2012 Introduction: Polyamidoamine (PAMAM) dendrimers are a unique family of dendritic polymers with numerous pharmaceutical and biomedical applications. One major problem with these polymers is their cytotoxicity.
Mohammad-Reza Rashidi +5 more
doaj +1 more source
Dual stimuli-responsive rotaxane-branched dendrimers with reversible dimension modulation
Nature Communications, 2018 With the aim of mimicking biological machines, in which the delicate arrangement of nanomechanical units lead to the output of specific functions upon the external stimulus, the construction of dual stimuli-responsive rotaxane-branched dendrimers was ...
Xu-Qing Wang +13 more
semanticscholar +1 more source
Advanced Materials, EarlyView.This review describes recent developments in the design and synthesis of metal–organic frameworks (MOF)/textile composites for the detoxification of chemical warfare agent and simulants with extensive discussion on the advantages and disadvantages of different methods.
Zhihua Cheng +4 more
wiley +1 more source
Light‐Emitting Diodes Based on Metal Halide Perovskite and Perovskite Related Nanocrystals
Advanced Materials, EarlyView.The review covers the past and current developments in light‐emitting diodes (LEDs) exploiting nanocrystals of halide perovskites and perovskite‐related materials. The review examines the aspects of material optimizations, device engineering, and applications.
Ying Liu +7 more
wiley +1 more source
Antigen targeting to dendritic cells: Still a place in future immunotherapy?
European Journal of Immunology, Volume 52, Issue 12, Page 1909-1924, December 2022., 2022 Dendritic cell‐based immunotherapy is a promising vaccination strategy to treat infectious diseases, autoimmunity, and cancer. In this review, we present an overview on the current state of antigen targeting approaches via C‐type lectin receptors, with an outlook on future developments and potential for clinical translation.
Patrizia Stoitzner +4 more
wiley +1 more source