Results 71 to 80 of about 31,221 (269)

Global Trends and Advances in Traumatic Brain Injury

Brain Health, EarlyView.
ABSTRACT Traumatic brain injury (TBI) remains a major global public health challenge, contributing substantially to morbidity and mortality while imposing a significant socioeconomic burden. In recent years, notable progress has been made in understanding TBI pathophysiology, classification, monitoring, and treatment.
Yuan Zhuang, Xixian Liao, Jiyao Jiang, Guoyi Gao   +3 more
wiley   +1 more source

High Charge Density in Peptide Dendrimers is Required to Destabilize Membranes: Insights into Endosome Evasion. [PDF]

Peptide dendrimers are a type of branched, symmetric, and topologically well-defined molecule that have already been used as delivery systems for nucleic acid transfection.
Machuqueiro, Miguel, Rodrigues, Filipe E P, Darbre, Tamis   +2 more
core   +1 more source

Dendrimers and their applications

, 2022
Dendrimers are symmetric molecules; their size is within the nanoscale. Its structure is usually homogeneous and monodisperse; they are composed of a nucleus and several layers 1. The number of layers that the dendrimer has defines its generation.
Fernández Rojas, Nathalie, Rojas Salas, María Fernanda, Santamaría Muñoz, Maripaz, Chavarría Rojas, Marianela, Solís Vindas, Grettel, González Corrales, Daniela, Matarrita Brenes, Daniela, Madrigal Redondo, German   +7 more
core   +1 more source

Thermally activated delayed fluorescence carbazole‐triazine dendrimer with bulky substituents

Aggregate
Carbazole‐triazine dendrimers with a bulky terminal substituent were synthesized, and the thermally activated delayed fluorescence (TADF) property was investigated.
Hiroki Ikebe, Kohei Nakao, Eri Hisamura, Minori Furukori, Yasuo Nakayama, Takuya Hosokai, Minlang Yang, Guanting Liu, Takuma Yasuda, Ken Albrecht   +9 more
doaj   +1 more source

Higher-generation type III-B rotaxane dendrimers with controlling particle size in three-dimensional molecular switching

Nature Communications, 2018
The complexity of rotaxane dendrimers poses a great synthetic challenge and the synthesis of higher generation rotaxane dendrimers has therefore rarely been reported. Here the authors report the synthesis of acid-base switchable rotaxane dendrimers up to
Chak-Shing Kwan, Rundong Zhao, Michel A. Van Hove, Zongwei Cai, Ken Cham-Fai Leung   +4 more
doaj   +1 more source

Syntheses of Sulfo-Glycodendrimers Using Click Chemistry and Their Biological Evaluation

Molecules, 2012
A series of novel glycol-clusters containing sulfonated N-acetyl-D-glucosamine (GlcNAc) have been synthesized using click chemistry. Three dendrimers with aromatic dendrons were synthesized using chlorination, azidation and click chemistries.
Tomohiro Fukuda, Yoshiko Miura, Shunsuke Onogi   +2 more
doaj   +1 more source

Fluorene‐based blue emitters: On the path to electrically pumped organic lasers

FlexMat, EarlyView.
Electrically pumped efficient operation remains unrealized, a major challenge in optoelectronics. Fluorene‐based blue‐emitting semiconductors are promising gain media, thanks to their structural tunability and favorable emission properties. This review summarizes recent advances, highlights their reliability and versatility in lasing, and outlines key ...
Yong Yan, Hao Li, Mengna Yu, Huiyin Wang, Jiangqiang He, Menghan Wu, Quanyou Feng, Linghai Xie   +7 more
wiley   +1 more source

Polymer informatics: Integrating data‐driven strategies, advanced machine learning, and automated synthesis for next‐generation polymer design

InfoScience, EarlyView.
Designing new polymers for applications such as sustainable plastics, biomaterials, and 3D printing has traditionally been slow and expensive, relying heavily on trial‐and‐error experiments. This review shows how polymer informatics—the integration of large polymer databases, machine‐learning models, and automated robotic synthesis—enables fast ...
Md. Saiful Islam, Tamanna Hoque, Junied Islam Shuvo, Sheta Roy Tori, Sadit Bihongo Malitha, Md. Zahangir Alam, A. M. Sarwaruddin Chowdhury   +6 more
wiley   +1 more source

Molecular analysis of interactions between dendrimers and asymmetric membranes at different transport stages

, 2014
Studying dendrimer-biomembrane interactions is important for understanding drug and gene delivery. In this study, coarse-grained molecular dynamics simulations were performed to investigate the behaviors of polyamidoamine (PAMAM) dendrimers (G4 and G5 ...
Qu ZG, Lu TJ, Qu, ZG (reprint author), Xi An Jiao Tong Univ, Minist Educ, Sch Energy & Power Engn, Key Lab Thermofluid Sci & Engn, Xian 710049, Peoples R China., Xu F, Wang JL(王九令), He XC, Shi XH(施兴华), Lin M   +7 more
core   +1 more source

Fluorescent Peptide Dendrimers for siRNA Transfection: Tracking pH Responsive Aggregation, siRNA Binding, and Cell Penetration [PDF]

, 2020
Transfecting nucleic acids into various cells is a key procedure in biological research also envisioned for therapeutic applications. In our effort to obtain simple reagents that would be readily accessible from commercial building blocks, we recently ...
Heitz, Marc, Javor, Sacha, Reymond, Jean-Louis, Zamolo, Susanna   +3 more
core   +1 more source