Results 71 to 80 of about 34,954 (198)

DNA Condensation by Partially Acetylated Poly(amido amine) Dendrimers: Effects of Dendrimer Charge Density on Complex Formation

open access: yesMolecules, 2013
The ability of poly(amido amine) (or PAMAM) dendrimers to condense semiflexible dsDNA and penetrate cell membranes gives them great potential in gene therapy and drug delivery but their high positive surface charge makes them cytotoxic. Here, we describe
Ronald G. Larson   +4 more
doaj   +1 more source

Novel Fluorescent Probe Based on Anthryl Dendron Having Oligo(ethyleneoxide) Groups at the Terminals [PDF]

open access: yes, 2008
Amphiphilic anthryl dendrons 5 and 6, which have carboxylate groups or oligo(ethyleneoxide) groups at the terminals, show solvatochromic properties. Reaction efficiency of photodimerization and dynamic light scattering (DLS) experiment of 5 and 6 reveal ...
Takaguchi, Yutaka, Yanagimoto, Yasushi
core   +1 more source

Synthesis of Inorganic Dendrimers

open access: yes, 2019
International audienceSummary Dendrimers are a special class of hyperbranched polymers, constituted of branched constitutional repeating units. Contrary to common polymers, dendrimers are not synthesized by polymerization reactions, but by the step-by ...
Anne-Marie Caminade   +1 more
core   +1 more source

Antiviral mechanism of polyanionic carbosilane dendrimers against HIV-1

open access: yes, 2016
Enrique Vacas-Córdoba,1–4 Marek Maly,5,6 Francisco J De la Mata,4,7 Rafael Gómez,4,7 Marjorie Pion,1–4 Mª Ángeles Muñoz-Fernández1–41Molecular Immunobiology Laboratory, General Universitary ...
Maly M   +5 more
core  

High Charge Density in Peptide Dendrimers is Required to Destabilize Membranes: Insights into Endosome Evasion. [PDF]

open access: yes
Peptide dendrimers are a type of branched, symmetric, and topologically well-defined molecule that have already been used as delivery systems for nucleic acid transfection.
Machuqueiro, Miguel   +2 more
core   +2 more sources

Molecular analysis of interactions between dendrimers and asymmetric membranes at different transport stages

open access: yes, 2014
Studying dendrimer-biomembrane interactions is important for understanding drug and gene delivery. In this study, coarse-grained molecular dynamics simulations were performed to investigate the behaviors of polyamidoamine (PAMAM) dendrimers (G4 and G5 ...
Qu ZG   +7 more
core   +1 more source

PAMAM-calix-dendrimers as carriers for 5-fluorouracil: complexation, aggregation, and in vitro antitumor activity

open access: yesChimica Techno Acta
Despite a number of serious challenges and limitations in clinical use, drug therapy is considered one of the most common approaches to treating cancer. However, many types of cancer become resistant to antitumor drugs.
Pavel Padnya   +10 more
doaj   +1 more source

Biocompatible Polyurea Dendrimers with pH‐Dependent Fluorescence

open access: yes, 2012
Biocompatible and biodegradable water‐soluble dendrimers comprising ureas within the interior and amino groups on the periphery were synthesized in supercritical carbon dioxide (dendrimer of generation 1 shown in picture).
Correia, I.J.   +5 more
core   +1 more source

Inorganic Dendrimers and Their Applications

open access: yes, 2019
International audienceSummary Dendrimers are a special class of hyperbranched polymers, constituted of branched constitutional repeating units. Contrary to common polymers, dendrimers are not synthesized by polymerization reactions, but by the step-by ...
Anne-Marie Caminade   +1 more
core   +1 more source

Synthesis and Characterization of Poly(Amidoamine) Dendrimers Encapsulatd 198Au Nanoparticles

open access: yesAtom Indonesia, 2012
Brachytherapy or internal radiotherapy is one of many methods used for treatment of cancer. This modality requires an agent with radionuclides that emits  or β particle with a proper energy.
R. Ritawidya1,2   +9 more
doaj  

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