Results 71 to 80 of about 34,954 (198)
The ability of poly(amido amine) (or PAMAM) dendrimers to condense semiflexible dsDNA and penetrate cell membranes gives them great potential in gene therapy and drug delivery but their high positive surface charge makes them cytotoxic. Here, we describe
Ronald G. Larson +4 more
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Novel Fluorescent Probe Based on Anthryl Dendron Having Oligo(ethyleneoxide) Groups at the Terminals [PDF]
Amphiphilic anthryl dendrons 5 and 6, which have carboxylate groups or oligo(ethyleneoxide) groups at the terminals, show solvatochromic properties. Reaction efficiency of photodimerization and dynamic light scattering (DLS) experiment of 5 and 6 reveal ...
Takaguchi, Yutaka, Yanagimoto, Yasushi
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Synthesis of Inorganic Dendrimers
International audienceSummary Dendrimers are a special class of hyperbranched polymers, constituted of branched constitutional repeating units. Contrary to common polymers, dendrimers are not synthesized by polymerization reactions, but by the step-by ...
Anne-Marie Caminade +1 more
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Antiviral mechanism of polyanionic carbosilane dendrimers against HIV-1
Enrique Vacas-Córdoba,1–4 Marek Maly,5,6 Francisco J De la Mata,4,7 Rafael Gómez,4,7 Marjorie Pion,1–4 Mª Ángeles Muñoz-Fernández1–41Molecular Immunobiology Laboratory, General Universitary ...
Maly M +5 more
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High Charge Density in Peptide Dendrimers is Required to Destabilize Membranes: Insights into Endosome Evasion. [PDF]
Peptide dendrimers are a type of branched, symmetric, and topologically well-defined molecule that have already been used as delivery systems for nucleic acid transfection.
Machuqueiro, Miguel +2 more
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Studying dendrimer-biomembrane interactions is important for understanding drug and gene delivery. In this study, coarse-grained molecular dynamics simulations were performed to investigate the behaviors of polyamidoamine (PAMAM) dendrimers (G4 and G5 ...
Qu ZG +7 more
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Despite a number of serious challenges and limitations in clinical use, drug therapy is considered one of the most common approaches to treating cancer. However, many types of cancer become resistant to antitumor drugs.
Pavel Padnya +10 more
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Biocompatible Polyurea Dendrimers with pH‐Dependent Fluorescence
Biocompatible and biodegradable water‐soluble dendrimers comprising ureas within the interior and amino groups on the periphery were synthesized in supercritical carbon dioxide (dendrimer of generation 1 shown in picture).
Correia, I.J. +5 more
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Inorganic Dendrimers and Their Applications
International audienceSummary Dendrimers are a special class of hyperbranched polymers, constituted of branched constitutional repeating units. Contrary to common polymers, dendrimers are not synthesized by polymerization reactions, but by the step-by ...
Anne-Marie Caminade +1 more
core +1 more source
Synthesis and Characterization of Poly(Amidoamine) Dendrimers Encapsulatd 198Au Nanoparticles
Brachytherapy or internal radiotherapy is one of many methods used for treatment of cancer. This modality requires an agent with radionuclides that emits or β particle with a proper energy.
R. Ritawidya1,2 +9 more
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