Results 11 to 20 of about 3,898 (197)

The dendritic engram

open access: yesFrontiers in Behavioral Neuroscience, 2023
Accumulating evidence from a wide range of studies, including behavioral, cellular, molecular and computational findings, support a key role of dendrites in the encoding and recall of new memories. Dendrites can integrate synaptic inputs in non-linear ways, provide the substrate for local protein synthesis and facilitate the orchestration of signaling ...
George Kastellakis   +5 more
openaire   +3 more sources

An ion‐percolating electrolyte membrane for ultrahigh efficient and dendrite‐free lithium metal batteries

open access: yesInfoMat, 2023
The development of lithium (Li) metal batteries has been severely limited by the formation of lithium dendrites and the associated catastrophic failure and inferior Coulombic efficiency which caused by non‐uniform or insufficient Li+ supply across the ...
Yu‐Ting Xu   +5 more
doaj   +1 more source

GABAB Receptor-Mediated Regulation of Dendro-Somatic Synergy in Layer 5 Pyramidal Neurons

open access: yesFrontiers in Cellular Neuroscience, 2021
Synergistic interactions between independent synaptic input streams may fundamentally change the action potential (AP) output. Using partial information decomposition, we demonstrate here a substantial contribution of synergy between somatic and apical ...
Jan M. Schulz   +3 more
doaj   +1 more source

Cell-Autonomous Control of Neuronal Dendrite Expansion via the Fatty Acid Synthesis Regulator SREBP

open access: yesCell Reports, 2017
Summary: During differentiation, neurons require a high lipid supply for membrane formation as they elaborate complex dendritic morphologies. While glia-derived lipids support neuronal growth during development, the importance of cell-autonomous lipid ...
Anna B. Ziegler   +7 more
doaj   +1 more source

Equicontinuous local dendrite maps

open access: yesApplied General Topology, 2021
Let X be a local dendrite, and f : X → X be a map. Denote by E(X) the set of endpoints of X. We show that if E(X) is countable, then the following are equivalent: (1) f is equicontinuous; (2)  fn (X) = R(f); (3) f|  fn (X) is equicontinuous; (4) f ...
Aymen Haj Salem   +2 more
doaj   +1 more source

A Novel Heptapeptide, GPPGPAG Transfers to the Brain, and Ameliorates Memory Dysfunction and Dendritic Atrophy in Alzheimer’s Disease Model Mice

open access: yesFrontiers in Pharmacology, 2021
We investigated the effects of a heptapeptide, GPPGPAG, on memory improvement and neuritic regeneration in Alzheimer’s disease models to evaluate its potency as a new anti-Alzheimer’s disease (AD) therapy. The anti-AD effects of GPPGPAG were evaluated in
Chihiro Tohda   +6 more
doaj   +1 more source

Dynamics and nanoscale organization of the postsynaptic endocytic zone at excitatory synapses

open access: yeseLife, 2022
At postsynaptic sites of neurons, a prominent clathrin-coated structure, the endocytic zone (EZ), controls the trafficking of glutamate receptors and is essential for synaptic plasticity.
Lisa AE Catsburg   +3 more
doaj   +1 more source

Phospholipid Homeostasis Regulates Dendrite Morphogenesis in Drosophila Sensory Neurons

open access: yesCell Reports, 2017
Summary: Disruptions in lipid homeostasis have been observed in many neurodevelopmental disorders that are associated with dendrite morphogenesis defects.
Shan Meltzer   +7 more
doaj   +1 more source

WDR47 protects neuronal microtubule minus ends from katanin-mediated severing

open access: yesCell Reports, 2021
Summary: Axons and dendrites are long extensions of neurons that contain arrays of noncentrosomal microtubules. Calmodulin-regulated spectrin-associated proteins (CAMSAPs) bind to and stabilize free microtubule minus ends and are critical for proper ...
Robin R. Buijs   +9 more
doaj   +1 more source

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