Results 71 to 80 of about 232,965 (327)

Voltage-gated calcium channels act upstream of adenylyl cyclase Ac78C to promote timely initiation of dendrite regeneration.

open access: yesPLoS Genetics
Most neurons are not replaced after injury and thus possess robust intrinsic mechanisms for repair after damage. Axon injury triggers a calcium wave, and calcium and cAMP can augment axon regeneration.
J Ian Hertzler   +7 more
doaj   +1 more source

Factors That Control the Formation of Dendrites and Other Morphologies on Lithium Metal Anodes

open access: yesFrontiers in Energy Research, 2019
Lithium metal is a promising anode material for next-generation rechargeable batteries, but non-uniform electrodeposition of lithium is a significant barrier.
Louise Frenck   +8 more
doaj   +1 more source

Topological entropy of transitive dendrite maps [PDF]

open access: yes, 2012
We show that every dendrite satisfying the condition that no subtree of it contains all free arcs admits a transitive, even exactly Devaney chaotic map with arbitrarily small entropy. This gives a partial answer to a question of Baldwin from 2001.Comment:
Špitalský, Vladimír
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells

open access: yeseLife, 2022
The precise control of growth and maintenance of the retinal ganglion cell (RGC) dendrite arborization is critical for normal visual functions in mammals. However, the underlying mechanisms remain elusive.
Fugui Niu   +12 more
doaj   +1 more source

Patterning of dendritic territories by dendrite-dendrite and dendrite-substrate interactions

open access: yes, 2014
Dendrites develop in highly complex environments and their interactions with neighboring neurons and the substrate are thought to be important for the establishment of their dendritic territories. Mechanisms required for the establishment of dendritic territories remain largely elusive.
openaire   +2 more sources

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Dendrite injury triggers neuroprotection in Drosophila models of neurodegenerative disease

open access: yesScientific Reports
Dendrite defects and loss are early cellular alterations observed across neurodegenerative diseases that play a role in early disease pathogenesis.
Sydney E. Prange   +9 more
doaj   +1 more source

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