Results 31 to 40 of about 778,422 (341)

Autophagy in dendritic cells [PDF]

Cellular & Molecular Immunology, 2018
Autophagy and immunity share the property of being auto-protective for the organism. Autophagy is an important degradation pathway that buffers nutrient deprivation by recycling macromolecules in organisms from yeast to man. Perturbations in autophagy are associated with inflammation and cancer development.
Ghislat, G., Lawrence, T.
openaire   +4 more sources

Junctional adhesion molecule-A is dispensable for myeloid cell recruitment and diversification in the tumor microenvironment

Frontiers in Immunology, 2022
Junctional adhesion molecule-A (JAM-A), expressed on the surface of myeloid cells, is required for extravasation at sites of inflammation and may also modulate myeloid cell activation.
Máté Kiss, Máté Kiss, Máté Kiss, Els Lebegge, Els Lebegge, Aleksandar Murgaski, Aleksandar Murgaski, Aleksandar Murgaski, Helena Van Damme, Helena Van Damme, Daliya Kancheva, Daliya Kancheva, Daliya Kancheva, Jan Brughmans, Jan Brughmans, Isabelle Scheyltjens, Isabelle Scheyltjens, Ali Talebi, Robin Maximilian Awad, Yvon Elkrim, Yvon Elkrim, Pauline M. R. Bardet, Pauline M. R. Bardet, Sana M. Arnouk, Sana M. Arnouk, Cleo Goyvaerts, Johan Swinnen, Frank Aboubakar Nana, Frank Aboubakar Nana, Jo A. Van Ginderachter, Jo A. Van Ginderachter, Damya Laoui, Damya Laoui   +32 more
doaj   +1 more source

From secretome analysis to immunology: chitosan induces major alterations in the activation of dendritic cells via a TLR4-dependent mechanism [PDF]

, 2009
Dendritic cells are known to be activated by a wide range of microbial products, leading to cytokine production and increased levels of membrane markers such as major histocompatibility complex class II molecules.
Arora, Behrens, Bellocchio, Berthier, Bittencourt, Chang, Chevallet, Chevallet, Chieppa, Curtsinger, de Saint-Vis, Dillon, Elliott, Faure, Gallucci, Gharahdaghi, Goetz, Johnson, Jørgensen, Kawai, Kennedy, Levitz, Luche, Maldonado-López, Murray, Owhashi, Peng, Perkins, Porporatto, Rabilloud, Rabilloud, Rabilloud, Richert, Romani, Seong, Shibata, Tada, Termeer, Underhill, Verhasselt, Wang, Yang, Young   +42 more
core   +5 more sources

Monocytes Elicit a Neutrophil-Independent Th1/Th17 Response Upon Immunization With a Mincle-Dependent Glycolipid Adjuvant

Frontiers in Immunology, 2022
Successful subunit vaccination with recombinant proteins requires adjuvants. The glycolipid trehalose-dibehenate (TDB), a synthetic analog of the mycobacterial cord factor, potently induces Th1 and Th17 immune responses and is a candidate adjuvant for ...
Christiane Desel, Peter J. Murray, Peter J. Murray, Christian H. K. Lehmann, Lukas Heger, Dennis Christensen, Peter Andersen, Matthias Mack, Diana Dudziak, Roland Lang   +9 more
doaj   +1 more source

Tetanic Stimulation Leads to Increased Accumulation of Ca^(2+)/Calmodulin-Dependent Protein Kinase II via Dendritic Protein Synthesis in Hippocampal Neurons [PDF]

, 1999
mRNA for the ɑ-subunit of CaMKII is abundant in dendrites of neurons in the forebrain (Steward, 1997). Here we show that tetanic stimulation of the Schaffer collateral pathway causes an increase in the concentration of ɑ-CaMKII in the dendrites of ...
Kennedy, Mary B., Kreiman, Gabriel, Ouyang, Yannan, Rosenstein, Alan, Schuman, Erin M.   +4 more
core   +1 more source

SnapShot: Dendritic Cells

Cell, 2011
[No abstract available]
Idoyaga, Juliana, Steinman, Ralph M.
openaire   +2 more sources

Measurement of Dipeptidylpeptidase Activity in vitro and in vivo

Bio-Protocol, 2017
Dipeptidylpeptidases (DPPs) are serine proteases, which cleave small proteins and peptides possessing a proline or an alanine in the second position of their N-terminus.
Rosa Barreira da Silva, Molly Ingersoll, Matthew Albert   +2 more
doaj   +1 more source

Revving up dendritic cells while braking PD-L1 to jump-start the cancer-immunity cycle motor [PDF]

, 2016
Although it is successful for some, most melanoma patients are refractory to T cell checkpoint inhibition. In this issue of Immunity, Merad and colleagues (2016) describe a dendritic-cell-based strategy to heighten the efficacy of therapeutic anti-PD-L1 ...
Coffelt, Seth B., de Visser, Karin E.
core   +1 more source

Exact solutions to cable equations in branching neurons with tapering dendrites [PDF]

, 2020
Neurons are biological cells with uniquely complex dendritic morphologies that are not present in other cell types. Electrical signals in a neuron with branching dendrites can be studied by cable theory which provides a general mathematical modelling ...
Timofeeva, Yulia, Yihe, Lu
core   +2 more sources

Defining dendritic cells

Current Opinion in Immunology, 2015
Dendritic cells (DCs) are versatile controllers of the immune system, best known for their potent ability to initiate adaptive immunity. Traditionally, DCs have been defined on the basis of cell morphology, expression of specific markers and select functional attributes such as the ability to migrate to T cell areas of secondary lymphoid organs and ...
Barbara U Schraml, Caetano Reis e Sousa
openaire   +3 more sources