Results 11 to 20 of about 468,502 (266)
Dendritic Cell-Based Immunotherapy: The Importance of Dendritic Cell Migration
Dendritic cells (DCs) are specialized antigen-presenting cells that are crucial for maintaining self-tolerance, initiating immune responses against pathogens, and patrolling body compartments.
Min-Seon Song +3 more
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Plasmacytoid dendritic cells: A dendritic cell in disguise
Since their discovery, the identity of plasmacytoid dendritic cells (pDCs) has been at the center of a continuous dispute in the field, and their classification as dendritic cells (DCs) has been recently re-challenged. pDCs are different enough from the rest of the DC family members to be considered a lineage of cells on their own. Unlike the exclusive
Rebeca Arroyo Hornero, Juliana Idoyaga
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The disabled dendritic cell [PDF]
ABSTRACT Dendritic cells are important antigen‐presenting cells of the immune system that induce and modulate immune responses. They interact with T and B lymphocytes as well as with natural killer cells to promote activation and differentiation of these cells.
M, Thurnher +4 more
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Intestinal dendritic cells [PDF]
PURPOSE OF REVIEW The intestinal immune system is constantly exposed to foreign antigens, which for the most part should be tolerated, but the immune system retains the ability to react rapidly and effectively to eliminate pathogens. Dendritic cells are at the front line in maintaining intestinal integrity as they are widely distributed within the ...
Schiavi Elisa +2 more
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Dendritic cells in atherosclerosis [PDF]
Atherosclerosis is a chronic inflammatory disease with activation of both the innate and adaptive arms of the immune system. Dendritic cells (DCs) are potent activators of adaptive immunity and have been identified in the normal arterial wall and within atherosclerotic lesions.
Manikandan, Subramanian, Ira, Tabas
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Monoclonal antibodies targeting co-inhibitory immune checkpoint molecules have been successful in clinical trials of both solid and hematological malignancies as acknowledged by the 2018 Nobel Prize in Medicine, however improving clinical response rates ...
Benjamin Y. Kong +12 more
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Dendritic Cells-Nature and Classification
Dendritic cells (DCs) are antigen (Ag)-presenting cells (APCs) characterized by a unique capacity to stimulate naïve T cells and initiate primary immune responses.
Katsuaki Sato, Shigeharu Fujita
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IOX1 impedes host inflammation in imiquimod-triggered psoriasis
Psoriasis is a chronic autoimmune disease with an unknown etiology and highly limited treatment strategies. The drugs currently used in the treatment of psoriasis are rarely recommended for long-term use owing to the serious side effects.
Joo Eun Shin +4 more
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The discovery of dendritic cells [PDF]
An excerpt from Ralph Steinman’s Harvey Lecture describing the discovery of dendritic cells.
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Dendritic cell (DC) defects are an important component of immunosuppression in cancer. Here, we assessed whether cancer could affect circulating DC populations and its correlation with tumor progression.
Alberto Pinzon-Charry +10 more
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