Results 21 to 30 of about 5,439,323 (304)
Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells [PDF]
Interactions between antigen-presenting dendritic cells (DCs) and T cells are essential for the induction of an immune response. However, during malaria infection, DC function is compromised and immune responses against parasite and heterologous antigens
Owain R Millington +34 more
core +1 more source
Dendritic cell (DC) defects are an important component of immunosuppression in cancer. Here, we assessed whether cancer could affect circulating DC populations and its correlation with tumor progression.
Alberto Pinzon-Charry +10 more
doaj +1 more source
Intestinal dendritic cells [PDF]
PURPOSE OF REVIEW The intestinal immune system is constantly exposed to foreign antigens, which for the most part should be tolerated, but the immune system retains the ability to react rapidly and effectively to eliminate pathogens. Dendritic cells are at the front line in maintaining intestinal integrity as they are widely distributed within the ...
Schiavi Elisa +2 more
openaire +5 more sources
The dendritic density field of a cortical pyramidal cell [PDF]
Much is known about the computation in individual neurons in the cortical column. Also, the selective connectivity between many cortical neuron types has been studied in great detail.
Hermann Cuntz +3 more
core +1 more source
Mechanisms and consequences of reduced dendritic growth of cerebellar Purkinje cells [PDF]
The cerebellum is a brain region crucial for coordination and motor learning. Being the principal output cell of the cerebellar cortex, Purkinje cell loss and degeneration play an important role in many cerebellar diseases.
Gugger, Olivia S.
core +1 more source
Tolerogenic Dendritic Cells [PDF]
▪ Abstract Dendritic cells (DCs) have several functions in innate and adaptive immunity. In addition, there is increasing evidence that DCs in situ induce antigen-specific unresponsiveness or tolerance in central lymphoid organs and in the periphery. In the thymus DCs generate tolerance by deleting self-reactive T cells.
Steinman, Ralph M. +2 more
openaire +2 more sources
Measurement of Dipeptidylpeptidase Activity in vitro and in vivo
Dipeptidylpeptidases (DPPs) are serine proteases, which cleave small proteins and peptides possessing a proline or an alanine in the second position of their N-terminus.
Rosa Barreira da Silva +2 more
doaj +1 more source
Junctional adhesion molecule-A (JAM-A), expressed on the surface of myeloid cells, is required for extravasation at sites of inflammation and may also modulate myeloid cell activation.
Máté Kiss +32 more
doaj +1 more source
“Immunity’s chain of command begins with antigen-presenting cells.”—Website describing the work of Ralph M.
openaire +2 more sources
Successful subunit vaccination with recombinant proteins requires adjuvants. The glycolipid trehalose-dibehenate (TDB), a synthetic analog of the mycobacterial cord factor, potently induces Th1 and Th17 immune responses and is a candidate adjuvant for ...
Christiane Desel +9 more
doaj +1 more source

