Results 91 to 100 of about 783,013 (308)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Dendritic Cell and Regulatory T Cell numbers in relation to Breast Cancer Progression and Metastasis [PDF]

International Journal of Medical Arts
Background: Breast cancer ranks as the second cause of cancer-related deaths in Egypt. Numerous immunomodulatory pathways underscore the immune system’s involvement in cancer prognosis.
Walaa Ashry, Amal Ayoub, Azza Ghanem, Amany Tawfeik, Effat Hassan   +4 more
doaj   +1 more source

Immunogens and Antigen Processing: Report from a Global HIV Vaccine Enterprise Working Group [PDF]

, 2010
The Global HIV Vaccine Enterprise convened a meeting of a Working Group in July 2009 to discuss recent progress in rational design of the components of an HIV vaccine, such as inserts, vectors and adjuvants,and in understanding antigen processing and ...
John Mascola, Ralph Steinman, Richter C. King, the Working Group convened by the Global HIV Vaccine Enterprise   +3 more
core   +3 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

SUBTYPE CHARACTERICS OF DENDRITIC CELLS FROM PERIPHERAL BLOOD OF PATIENTS WITH RHEUMATOID ARTHRITIS

Медицинская иммунология, 2014
. Characteristics of myeloid and plasmacytoid dendritic cells from peripheral blood were studied in healthy donors and patients with rheumatoid arthritis (RA).
S. A. Falaleeva, V. V. Kurilin, N. S. Shkaruba, O. A. Chumasova, A. E. Sizikov, S. V. Sennikov   +5 more
doaj   +1 more source

Leukemic dendritic cells

Терапевтический архив, 2008
I V Gal'tseva, L E Pashin, V G Savchenko
doaj   +2 more sources

Electrophysiology of glioma: a Rho GTPase-activating protein reduces tumor growth and spares neuron structure and function [PDF]

, 2016
Background. Glioblastomas are the most aggressive type of brain tumor. A successful treatment should aim at halting tumor growth and protecting neuronal cells to prevent functional deficits and cognitive deterioration.
Ammassari-Teule, M, Baroncelli, L, Caleo, M, Costa, M, de Graaf, El, Fabbri, A, Fiorentini, C, Mcdonnell, L, Middei, S, Olimpico, F, Schmidt, G, Vannini, E   +11 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Endothelial cell-derived microparticles induce plasmacytoid dendritic cell maturation: potential implications in inflammatory diseases

Haematologica, 2009
Background Increased circulating endothelial microparticles, resulting from vascular endothelium dysfunction, and plasmacytoid dendritic cell activation are both encountered in common inflammatory disorders.
Fanny Angelot, Estelle Seillès, Sabeha Biichlé, Yael Berda, Béatrice Gaugler, Joel Plumas, Laurence Chaperot, Françoise Dignat-George, Pierre Tiberghien, Philippe Saas, Francine Garnache-Ottou   +10 more
doaj   +1 more source

Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative processes. [PDF]

, 2015
BackgroundDendritic simplification, a key feature of the neurodegenerative triad of Alzheimer's disease (AD) in addition to spine changes and neuron loss, occurs in a region-specific manner.
Bakota, Lidia, Ballatore, Carlo, Brandt, Roland, Golovyashkina, Nataliya, Penazzi, Lorène, Smith, Amos B   +5 more
core   +1 more source