Results 81 to 90 of about 4,483,430 (258)

Plasticity in gene expression programmes of dendritic cells responding to antigens. [PDF]

open access: yes, 2005
Dendritic cells (DCs) are professional antigen presenting cells whose function is to initiate and shape an appropriate adaptive immune response. This requires an ability to distinguish differences between whole pathogens, in order to orchestrate ...
Kwan, A.P-Y., Kwan, Antonia Pui-Yue
core  

T-Cell Stimulation by Melanoma RNA-Pulsed Dendritic Cells [PDF]

open access: yes, 2004
In situations where well-established approaches such as surgery, radiation therapy and chemotherapy fail to help cancer patients, immunotherapy has the potential to be an effective alternative.
Javorovic, Miran
core   +1 more source

SUBTYPE CHARACTERICS OF DENDRITIC CELLS FROM PERIPHERAL BLOOD OF PATIENTS WITH RHEUMATOID ARTHRITIS

open access: yesМедицинская иммунология, 2014
. Characteristics of myeloid and plasmacytoid dendritic cells from peripheral blood were studied in healthy donors and patients with rheumatoid arthritis (RA).
S. A. Falaleeva   +5 more
doaj   +1 more source

Dendritic cell metabolism [PDF]

open access: yesNature Reviews Immunology, 2014
The past 15 years have seen enormous advances in our understanding of the receptor and signalling systems that allow dendritic cells (DCs) to respond to pathogens or other danger signals and initiate innate and adaptive immune responses. We are now beginning to appreciate that many of these pathways not only stimulate changes in the expression of genes
Pearce, E.J., Everts, B.
openaire   +4 more sources

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

EFFICIENCY EVALUATION OF THE HOME-PRODUCED RECOMBINANT HUMAN CYTOKINES FROM the sci-store.ru FOR GENERATION OF MONOCYTE-DERIVED DENDRITIC CELLS

open access: yesМедицинская иммунология, 2018
Dendritic cells are specialized antigen-presenting cells which are required to involve naive T-lymphocytes into immune response. Dendritic cells are used in numerous research studies, and have also found practical application as a main component of ...
V. Yu. Talayev   +3 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

An investigation into the consequences of Salmonella infection of murine macrophages and dendritic cells: relevance to reactive arthritis. [PDF]

open access: yes, 2006
Reactive arthritis (ReA) is a sterile joint inflammation triggered by bacterial infection and is associated with the MHC class I molecule HLA-B27. Bacterial antigens have been detected in synovial tissues from ReA patients, but how they are transported ...
Zhao, C., Zhao, Chun Fang
core  

Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells

open access: yesHaematologica, 2010
Background The immunoregulatory enzyme indoleamine 2,3-dioxygenase, which catalyzes the conversion of tryptophan into kynurenine, is expressed in a significant subset of patients with acute myeloid leukemia, resulting in the inhibition of T-cell ...
Antonio Curti   +11 more
doaj   +1 more source

Defining dendritic cells

open access: yesCurrent Opinion in Immunology, 2015
Dendritic cells (DCs) are versatile controllers of the immune system, best known for their potent ability to initiate adaptive immunity. Traditionally, DCs have been defined on the basis of cell morphology, expression of specific markers and select functional attributes such as the ability to migrate to T cell areas of secondary lymphoid organs and ...
Barbara U Schraml, Caetano Reis e Sousa
openaire   +2 more sources

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