Results 61 to 70 of about 783,013 (308)

Paradigm shift in dendritic cell-based immunotherapy: from in vitro generated monocyte-derived DCs to naturally circulating DC subsets

Frontiers in Immunology, 2014
Dendritic cell-based immunotherapy employs the patients’ immune system to fight neoplastic lesions spread over the entire body. This makes it an important therapy option for patients suffering from metastatic melanoma, which is often resistant to ...
Florian eWimmers, Gerty eSchreibelt, Annette E. Sköld, Carl G. Figdor, I. Jolanda M. ede Vries, I. Jolanda M. ede Vries   +5 more
doaj   +1 more source

Function and autophagy of monocyte-derived dendritic cells is affected by hepatitis B virus infection

BMC Immunology, 2023
Background The role of dendritic cells and the autophagy state of dendritic cells in the immune response of hepatitis B virus (HBV) infection was still controversial.
Hua Xu, Juan Kang, Shan Zhong, Min Chen, Peng Hu, Hong Ren, Zhi Zhou, Yu Lei   +7 more
doaj   +1 more source

Expression of thyroglobulin on follicular dendritic cells of thyroid mucosa-associated lymphoid tissue (MALT) lymphoma [PDF]

, 2009
Reportedly, thyroid mucosa-associated lymphoid tissue (MALT) lymphoma is closely associated with Hashimoto's thyroiditis. However, it remains unknown which antigen is closely associated with thyroid MALT lymphoma.
Akagi, Tadaatsu, Kobayashi, Keita, Mannami, Tomohiko, Miyake, Takayoshi, Munemasa, Mitsuru, Sakugawa, Sumie Takase, Shinagawa, Katsuji, Tanimoto, Mitsune, Yoshino, Tadashi   +8 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

CD1c-related DCs that express CD207/langerin, but are distinguishable from Langerhans cells, are consistently present in human tonsils

Frontiers in Immunology, 2016
Several subsets of dendritic cells (DCs) are present in the oropharyngeal tonsillar tissues and are thought to behave as major actors in development and regulation of immunity by acting as a first line of recognition for airborne and alimentary antigens.
Anne eDe Monte, Anne eDe Monte, Anne eDe Monte, Charles-Vivien eOLIVIERI, Charles-Vivien eOLIVIERI, Sebastien eVITALE, Sonanda eBAILLEUX, Laurent eCASTILLO, Valerie eGIORDANENGO, Janet L MARYANSKI, Janet L MARYANSKI, Elodie eSegura, Alain eDOGLIO, Alain eDOGLIO   +13 more
doaj   +1 more source

Dendritic cell subsets in the intestinal lamina propria: ontogeny and function [PDF]

, 2013
The intestinal mucosa is exposed to large amounts of foreign antigen (Ag) derived from commensal bacteria, dietary Ags, and intestinal pathogens. Dendritic cells (DCs) are believed to be involved in the induction of tolerance to harmless Ags and in ...
Agace, Agace, Agace, Aliberti, Anjuere, Annacker, Bachem, Bachem, Bain, Banchereau, Bedoui, Bogunovic, Carter, Cebula, Cerovic, Chervonsky, Coombes, Crozat, Cruickshank, del Rio, del Rio, Denning, Diehl, Edelson, Edelson, Farache, Forster, Fujimoto, Ginhoux, Greter, Hadis, Halle, Hammerschmidt, Haniffa, Hildner, Hoshi, Ichikawa, Iwata, Jackson, Jaensson, Jaensson-Gyllenback, Jang, Johansson-Lindbom, Johansson-Lindbom, Jones, Jongbloed, Kinnebrew, Kobayashi, Kusunoki, Lewis, Liu, Macpherson, Maynard, McDole, Merad, Miller, Milling, Molenaar, Mucida, Naik, Naik, Niess, Onai, Persson, Poulin, Poulin, Rescigno, Rivollier, Sathaliyawala, Schlitzer, Schulz, Scott, Siddiqui, Sun, Svensson, Tamoutounour, Travis, Uematsu, Uematsu, Vallon-Eberhard, Varol, Vremec, Weiss, Worbs, Wu, Zeng, Zhan, Zigmond   +87 more
core   +1 more source

Dendritic Cell Differentiation [PDF]

The Journal of Immunology, 2004
Dauer et al. ([1][1]) presented a method to differentiate CD14+ cells into mature dendritic cells (DC) within 48 h (FastDC). FastDC displayed a DC-like morphology, down-regulated CD14, and induced proliferation of autologous T cells against soluble Ags as efficiently as standard monocyte-derived ...
Curti A, Ferri E, Pandolfi S, Isidori A, LEMOLI, ROBERTO MASSIMO   +4 more
openaire   +4 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Cutaneous blastic plasmacytoid dendritic cell neoplasm: Report of a case and review of the literature

Dermatologica Sinica, 2017
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy that usually occurs in elderly individuals and manifests with skin lesions followed by involvement of the lymph nodes, bone marrow, and peripheral blood.
Chien-yio Lin, Ming-Ying Wu, Tseng-tong Kuo, Pei-Hsuan Lu   +3 more
doaj   +1 more source

Functional identification of dendritic cells in the teleost model, rainbow trout (Oncorhynchus mykiss). [PDF]

PLoS ONE, 2012
Dendritic cells are specialized antigen presenting cells that bridge innate and adaptive immunity in mammals. This link between the ancient innate immune system and the more evolutionarily recent adaptive immune system is of particular interest in fish ...
Elizabeth Bassity, Theodore G Clark
doaj   +1 more source