Results 61 to 70 of about 4,483,430 (258)

In Vitro and In Vivo Effects of Ketamine on Generation and Function of Dendritic Cells

Journal of Pharmacological Sciences, 2011
.: The question about how intravenous anesthetic reagents affect the development and function of dendritic cell subsets still has no comprehensive answers.
Jingxian Zeng, Shuxuan Xia, Wa Zhong, Jie Li, Liling Lin   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Endocytosis of Potential Contact Sensitizers by Human Dendritic Cells

, 1993
Several lines of evidence indicates that a population of lymphoid cells occurring in most organs of the body with a dendritic morphology is of prime importance in the initial stages of immune responses (1).
Marie Larsson, Larsson, Marie,, Urban Forsum, Forsum, Urban,   +3 more
core   +1 more source

Plasmacytoid dendritic cells in dermatology, [PDF]

Anais Brasileiros de Dermatologia
Plasmacytoid dendritic cells are part of the dendritic cells family and are a relevant link between innate and adaptive immunity. They are the most potent producers of type 1 interferon, generating antiviral response, stimulating macrophages and ...
Natasha Favoretto Dias de Oliveira, Claudia Giuli Santi, Celina Wakisaka Maruta, Valeria Aoki   +3 more
doaj   +2 more sources

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Skin TLR7 triggering promotes accumulation of respiratory dendritic cells and natural killer cells. [PDF]

, 2012
The TLR7 agonist imiquimod has been used successfully as adjuvant for skin treatment of virus-associated warts and basal cell carcinoma. The effects of skin TLR7 triggering on respiratory leukocyte populations are unknown.
Lohmeyer, Jürgen, Werner von Wulffen (141047), Gruber, Achim D., Gregor Bein (141053), Knoche, Angela, Kershaw, Olivia, Kranz, Sabine, Angela Knoche (141037), Holger Hackstein (141030), Hagel, Nicole, Angela Knoche, Wulffen, Werner von, Olivia Kershaw (141049), Holger Hackstein, Olivia Kershaw, Achim D. Gruber (141051), Nicole Hagel, Gregor Bein, Jürgen Lohmeyer, Sabine Kranz, Nicole Hagel (141033), Baal, Nelli, Bein, Gregor, Achim D Gruber, Jürgen Lohmeyer (141044), Nelli Baal (141055), Hackstein, Holger, Nelli Baal, Werner von Wulffen, Sabine Kranz (141040)   +29 more
core   +2 more sources

The Role of Tolerogenic Dendritic Cell Therapy in Autoimmune Diseases

مجله دانشکده پزشکی اصفهان, 2018
Dendritic cells (DCs) are special antigen-presenting cells that are important for activation of immune response and tolerance. Dendritic cells have been divided in two subtypes of conventional and plasmacytoid dendritic cells.
Maryam Shahidi, Seyed Mahmoud Hashemi, Davar Amani, Kaveh Baghaei   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

IMMUNOTHERAPEUTIC ACTION OF T-BET GENE MODIFIED DENDRITIC CELLS [PDF]

, 2013
T-bet is a Type-1 transcription factor that regulates the development of Type-1 T cell and Type-1 anti-tumor immunity. T-bet expression in Dendritic Cells (DC) is required for the ability of these antigen-presenting cells (APC) to prime Type-1-polarized ...
Chen, Lu
core  

Full restoration of Brucella-infected dendritic cell functionality through Vγ9Vδ2 T helper type 1 crosstalk. [PDF]

PLoS ONE, 2012
Vγ9Vδ2 T cells play an important role in the immune response to infectious agents but the mechanisms contributing to this immune process remain to be better characterized.
Ming Ni, Delphine Martire, Emmanuel Scotet, Marc Bonneville, Francoise Sanchez, Virginie Lafont   +5 more
doaj   +1 more source