Results 41 to 50 of about 5,310,926 (308)
Virulence, 2012 “Immunity’s chain of command begins with antigen-presenting cells.”—Website describing the work of Ralph M.
openaire +2 more sources
Subsets of migrating intestinal dendritic cells [PDF]
, 2010 Dendritic cells (DCs) in the intestine are heterogeneous. Phenotypically different populations of conventional DCs have been identified in the intestinal lamina propria, Peyer's patches, and in the draining mesenteric lymph nodes, to which these DCs ...
Yrlid, Ulf +4 more
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PLoS ONE, 2013 Dendritic cells are the professional antigen presenting cells of innate immunity and key players in maintaining the balance of immune responses. Studies with dendritic cells are mainly limited by their low numbers in vivo and their difficult maintenance ...
Cornelia Richter +5 more
doaj +1 more source
Tolerogenic Dendritic Cells [PDF]
Annual Review of Immunology, 2003 ▪ Abstract Dendritic cells (DCs) have several functions in innate and adaptive immunity. In addition, there is increasing evidence that DCs in situ induce antigen-specific unresponsiveness or tolerance in central lymphoid organs and in the periphery. In the thymus DCs generate tolerance by deleting self-reactive T cells.
Steinman, Ralph M. +2 more
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Genome Wide Transcriptome Analysis of Dendritic Cells Identifies Genes with Altered Expression in Psoriasis [PDF]
, 2013 Activation of dendritic cells by different pathogens induces the secretion of proinflammatory mediators resulting in local inflammation. Importantly, innate immunity must be properly controlled, as its continuous activation leads to the development of ...
Szász, András +27 more
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Therapeutic dendritic cell vaccination against human papillomavirus [PDF]
, 2009 Cervical cancer, which is caused by infection with human papillomavirus (HPV), is the second most common cancer among women worldwide, leading to 230000 deaths annually.
Nurkkala Karlsson, Merja
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Nature Communications, 2019 The Wnt pathway regulates anti-tumour immunity in melanoma. Here, the authors show that, in lung adenocarcinoma, secretion of the ligand Wnt1 induces immune resistance by impairing the ability of dendritic cells to cross-prime T cells, and that blocking ...
Dimitra Kerdidani +14 more
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Involvement of suppressive B-lymphocytes in the mechanism of tolerogenic dendritic cell reversal of type 1 diabetes in NOD mice. [PDF]
PLoS ONE, 2014 The objective of the study was to identify immune cell populations, in addition to Foxp3+ T-regulatory cells, that participate in the mechanisms of action of tolerogenic dendritic cells shown to prevent and reverse type 1 diabetes in the Non-Obese ...
Valentina Di Caro +5 more
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The use of wavelength modulated Raman spectroscopy in label-free identification of T lymphocyte subsets, natural killer cells and dendritic cells [PDF]
, 2015 This work was funded by a Cancer Research United Kingdom, Engineering and Physical Sciences Research Council (grant EP/J01771X/1), Medical Research Council and Department of Health England Imaging Programme (MC, MM KD), and by A European Union FAMOS ...
Barbosa, Joao +29 more
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Identification of proteases employed by dendritic cells in the processing of protein purified derivative (PPD) [PDF]
, 2004 Dendritic cells (DC) are known to present exogenous protein Ag effectively to T cells. In this study we sought to identify the proteases that DC employ during antigen processing.
Mansour Mohamadzadeh +9 more
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