Results 21 to 30 of about 5,310,926 (308)
Dendritic cell regulation of immunity to Leishmania donovani [PDF]
, 2010 Dendritic cells lie at the interface of innate and adaptive immunity, critically contributing to the generation of an antigen-specific immune response.
Owens, Benjamin M.J.
core +5 more sources
eLife, 2018 Type I interferon (IFN-I) responses are critical for the control of RNA virus infections, however, many viruses, including Dengue (DENV) and Chikungunya (CHIKV) virus, do not directly activate plasmacytoid dendritic cells (pDCs), robust IFN-I producing ...
Brian Webster +12 more
doaj +1 more source
The disabled dendritic cell [PDF]
The FASEB Journal, 2001 ABSTRACT Dendritic cells are important antigen‐presenting cells of the immune system that induce and modulate immune responses. They interact with T and B lymphocytes as well as with natural killer cells to promote activation and differentiation of these cells.
M, Thurnher +4 more
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Dendritic Cells Revisited [PDF]
Annual Review of Immunology, 2021 Dendritic cells (DCs) possess the ability to integrate information about their environment and communicate it to other leukocytes, shaping adaptive and innate immunity. Over the years, a variety of cell types have been called DCs on the basis of phenotypic and functional attributes.
Cabeza-Cabrerizo, Mar +4 more
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Dendritic cells in human renal inflammation - Part II [PDF]
, 2011 Dendritic cells (DCs) are bone marrow-derived professional antigen-presenting cells that act as master regulators of acquired and innate immune responses. Here, we review the available information on their role in human renal inflammation.
Elfriede Noessner +15 more
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Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells [PDF]
, 2007 Interactions between antigen-presenting dendritic cells (DCs) and T cells are essential for the induction of an immune response. However, during malaria infection, DC function is compromised and immune responses against parasite and heterologous antigens
Owain R Millington +33 more
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Dendritic Cells and Their Multiple Roles during Malaria Infection
Journal of Immunology Research, 2016 Dendritic cells (DCs) play a central role in the initiation of adaptive immune responses, efficiently presenting antigens to T cells. This ability relies on the presence of numerous surface and intracellular receptors capable of sensing microbial ...
Kelly N. S. Amorim +3 more
doaj +1 more source
Intestinal dendritic cells [PDF]
Current Opinion in Gastroenterology, 2015 PURPOSE OF REVIEW The intestinal immune system is constantly exposed to foreign antigens, which for the most part should be tolerated, but the immune system retains the ability to react rapidly and effectively to eliminate pathogens. Dendritic cells are at the front line in maintaining intestinal integrity as they are widely distributed within the ...
Schiavi Elisa +2 more
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Skin-derived dendritic cells acquire and degrade the scrapie agent following in vitro exposure [PDF]
, 2005 The accumulation of the scrapie agent in lymphoid tissues following inoculation via the skin is critical for efficient neuroinvasion, but how the agent is initially transported from the skin to the draining lymph node is not known. Langerhans cells (LCs)
Hopkins, John +5 more
core +1 more source
Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity
Cell Reports, 2020 Summary: Human dendritic cells (DCs) comprise subsets with distinct phenotypic and functional characteristics, but the transcriptional programs that dictate their identity remain elusive.
Rebecca Leylek +9 more
doaj +1 more source