Results 11 to 20 of about 467,600 (266)
Dendritic Cells Revisited [PDF]
Annual Review of Immunology, 2021 Dendritic cells (DCs) possess the ability to integrate information about their environment and communicate it to other leukocytes, shaping adaptive and innate immunity. Over the years, a variety of cell types have been called DCs on the basis of phenotypic and functional attributes.
Mar Cabeza-Cabrerizo +2 more
exaly +3 more sources
IL-7-Adjuvanted Vaginal Vaccine Elicits Strong Mucosal Immune Responses in Non-Human Primates
Frontiers in Immunology, 2021 Mucosal immune responses are crucial in protecting against pathogens entering through mucosal surfaces. However, due to poor T-cell responsiveness upon mucosal antigenic stimulation, mucosal immunity remains difficult to obtain through vaccines and ...
Sandrine Logerot +9 more
doaj +1 more source
Systemic bacterial infections affect dendritic cell development and function
International Journal of Medical Microbiology, 2021 Dendritic cells (DCs) are critical in host defense against infection. DC depletion is an early event in the course of sepsis that may impair the host defense mechanisms.
Kristin Bieber +3 more
doaj +1 more source
Plasmacytoid dendritic cells: A dendritic cell in disguise
Molecular Immunology, 2023 Since their discovery, the identity of plasmacytoid dendritic cells (pDCs) has been at the center of a continuous dispute in the field, and their classification as dendritic cells (DCs) has been recently re-challenged. pDCs are different enough from the rest of the DC family members to be considered a lineage of cells on their own. Unlike the exclusive
Rebeca Arroyo Hornero, Juliana Idoyaga
openaire +2 more sources
Molecular Biomedicine, 2021 Interleukins (IL)-17A and F are critical cytokines in anti-microbial immunity but also contribute to auto-immune pathologies. Recent evidence suggests that they may be differentially produced by T-helper (Th) cells, but the underlying mechanisms remain ...
Karla Fabiola Corral-Jara +6 more
doaj +1 more source
Deciphering the combinatorial landscape of immunity
eLife, 2020 From cellular activation to drug combinations, immunological responses are shaped by the action of multiple stimuli. Synergistic and antagonistic interactions between stimuli play major roles in shaping immune processes.
Antonio Cappuccio +5 more
doaj +1 more source
Regulation of the Migration of Distinct Dendritic Cell Subsets
Frontiers in Cell and Developmental Biology, 2021 Dendritic cells (DCs), a class of antigen-presenting cells, are widely present in tissues and apparatuses of the body, and their ability to migrate is key for the initiation of immune activation and tolerogenic immune responses.
Meng Feng +5 more
doaj +1 more source
Differential gene expression in thrombomodulin (TM; CD141)(+) and TM(-) dendritic cell subsets. [PDF]
PLoS ONE, 2013 Previously we have shown in a mouse model of bronchial asthma that thrombomodulin can convert immunogenic conventional dendritic cells into tolerogenic dendritic cells while inducing its own expression on their cell surface.
Masaaki Toda +9 more
doaj +1 more source
OVA-PEG-R848 nanocapsules stimulate neonatal conventional and plasmacytoid dendritic cells
Frontiers in Pediatrics, 2022 Childhood mortality represents a major issue with 5. 3 million worldwide deaths of children under 5 years of age in 2019. Approximately half of those deaths can be attributed to easily preventable, infectious diseases.
Sebastian Wirsching +12 more
doaj +1 more source
The disabled dendritic cell [PDF]
The FASEB Journal, 2001 ABSTRACT Dendritic cells are important antigen‐presenting cells of the immune system that induce and modulate immune responses. They interact with T and B lymphocytes as well as with natural killer cells to promote activation and differentiation of these cells.
M, Thurnher +4 more
openaire +2 more sources