Results 11 to 20 of about 783,013 (308)
Involvement of suppressive B-lymphocytes in the mechanism of tolerogenic dendritic cell reversal of type 1 diabetes in NOD mice. [PDF]
PLoS ONE, 2014 The objective of the study was to identify immune cell populations, in addition to Foxp3+ T-regulatory cells, that participate in the mechanisms of action of tolerogenic dendritic cells shown to prevent and reverse type 1 diabetes in the Non-Obese ...
Valentina Di Caro +5 more
doaj +19 more sources
Dendritic cell metabolism [PDF]
Nature Reviews Immunology, 2014 The past 15 years have seen enormous advances in our understanding of the receptor and signalling systems that allow dendritic cells (DCs) to respond to pathogens or other danger signals and initiate innate and adaptive immune responses. We are now beginning to appreciate that many of these pathways not only stimulate changes in the expression of genes
Pearce, E.J., Everts, B.
openaire +6 more sources
Allergology International, 2007 Dendritic cells (DC) play key rolls in various aspects of immunity. The functions of DC depend on the subsets as well as their location or activation status.
Satoshi Takeuchi, Masutaka Furue
doaj +3 more sources
IL-7-Adjuvanted Vaginal Vaccine Elicits Strong Mucosal Immune Responses in Non-Human Primates
Frontiers in Immunology, 2021 Mucosal immune responses are crucial in protecting against pathogens entering through mucosal surfaces. However, due to poor T-cell responsiveness upon mucosal antigenic stimulation, mucosal immunity remains difficult to obtain through vaccines and ...
Sandrine Logerot +9 more
doaj +1 more source
Systemic bacterial infections affect dendritic cell development and function
International Journal of Medical Microbiology, 2021 Dendritic cells (DCs) are critical in host defense against infection. DC depletion is an early event in the course of sepsis that may impair the host defense mechanisms.
Kristin Bieber +3 more
doaj +1 more source
Manufacturing Dendritic Cells for Immunotherapy: Monocyte Enrichment [PDF]
, 2020 Dendritic cells play a key role in activation of the immune system as potent antigen-presenting cells. This pivotal position, along with the ability to generate dendritic cells from monocytes and ready uptake of antigen, makes them an intriguing vehicle ...
Cox, Cheryl, Hopewell, Emily L.
core +1 more source
Dendritic Cells Revisited [PDF]
Annual Review of Immunology, 2021 Dendritic cells (DCs) possess the ability to integrate information about their environment and communicate it to other leukocytes, shaping adaptive and innate immunity. Over the years, a variety of cell types have been called DCs on the basis of phenotypic and functional attributes.
Cabeza-Cabrerizo, Mar +4 more
openaire +2 more sources
Molecular Biomedicine, 2021 Interleukins (IL)-17A and F are critical cytokines in anti-microbial immunity but also contribute to auto-immune pathologies. Recent evidence suggests that they may be differentially produced by T-helper (Th) cells, but the underlying mechanisms remain ...
Karla Fabiola Corral-Jara +6 more
doaj +1 more source
Deciphering the combinatorial landscape of immunity
eLife, 2020 From cellular activation to drug combinations, immunological responses are shaped by the action of multiple stimuli. Synergistic and antagonistic interactions between stimuli play major roles in shaping immune processes.
Antonio Cappuccio +5 more
doaj +1 more source
Regulation of the Migration of Distinct Dendritic Cell Subsets
Frontiers in Cell and Developmental Biology, 2021 Dendritic cells (DCs), a class of antigen-presenting cells, are widely present in tissues and apparatuses of the body, and their ability to migrate is key for the initiation of immune activation and tolerogenic immune responses.
Meng Feng +5 more
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