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Plasmacytoid Dendritic Cells and Cancer Immunotherapy [PDF]
Cells, 2022 Despite largely disappointing clinical trials of dendritic cell (DC)-based vaccines, recent studies have shown that DC-mediated cross-priming plays a critical role in generating anti-tumor CD8 T cell immunity and regulating anti-tumor efficacy of ...
Chunmei Fu +3 more
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Plasmacytoid dendritic cells in dermatology, [PDF]
Anais Brasileiros de Dermatologia, 2021 Plasmacytoid dendritic cells are part of the dendritic cells family and are a relevant link between innate and adaptive immunity. They are the most potent producers of type 1 interferon, generating antiviral response, stimulating macrophages and ...
Natasha Favoretto Dias de Oliveira +3 more
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Plasmacytoid dendritic cells in atherosclerosis [PDF]
Frontiers in Physiology, 2012 Atherosclerosis, a chronic inflammatory disease of the vessel wall and the underlying cause of cardiovascular disease, is initiated and maintained by innate and adaptive immunity.
Yvonne eDöring, Alma eZernecke
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Plasmacytoid dendritic cells: A dendritic cell in disguise. [PDF]
Mol Immunol, 2023 Since their discovery, the identity of plasmacytoid dendritic cells (pDCs) has been at the center of a continuous dispute in the field, and their classification as dendritic cells (DCs) has been recently re-challenged. pDCs are different enough from the rest of the DC family members to be considered a lineage of cells on their own. Unlike the exclusive
Arroyo Hornero R, Idoyaga J.
europepmc +3 more sources
Disease-Associated Plasmacytoid Dendritic Cells [PDF]
Frontiers in Immunology, 2017 Plasmacytoid dendritic cells (pDCs), also called natural interferon (IFN)-producing cells, represent a specialized cell type within the innate immune system.
Shuang Li +5 more
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The multifaceted biology of plasmacytoid dendritic cells [PDF]
Nature Reviews Immunology, 2015 Plasmacytoid dendritic cells (pDCs) are a unique DC subset that specializes in the production of type I interferons (IFNs). pDCs promote antiviral immune responses and have been implicated in the pathogenesis of autoimmune diseases that are characterized by a type I IFN signature. However, pDCs can also induce tolerogenic immune responses.
Marco Colonna, Melissa Swiecki
exaly +3 more sources
Proliferation of CD10+ mature plasmacytoid dendritic cells in lymph nodes of patients with chronic non-tuberculous mycobacterial infection: a case report [PDF]
Journal of Medical Case ReportsBackground Plasmacytoid dendritic cells are essential immune system components, critical in antiviral and antibacterial defense. Although plasmacytoid dendritic cells are typically present in small numbers in the peripheral blood, bone marrow, and lymph ...
Longyi Zhang +4 more
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The Role of Plasmacytoid Dendritic Cells in Cancers
Frontiers in Immunology, 2021 Plasmacytoid dendritic cells (pDCs) are a special subtype of dendritic cells with the morphology of plasma cells. pDCs produce massive amounts of type I interferon (IFN-I), which was originally found to play an extremely pivotal role in antiviral immunity.
Yinming Liang, Toby Lawrence
exaly +5 more sources
Role of plasmacytoid dendritic cells in vascular dysfunction in mice with renovascular hypertension [PDF]
HeliyonEndothelial dysfunction and inflammation are clinically significant risk factors for cardiovascular diseases in hypertension. Although immune cells play a role in hypertension, the impact of plasmacytoid dendritic cells in established renovascular ...
Balaji Srinivas +4 more
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Human Plasmacytoid Dendritic Cells and Cutaneous Melanoma
Cells, 2020 The prognosis of metastatic melanoma (MM) patients has remained poor for a long time. However, the recent introduction of effective target therapies (BRAF and MEK inhibitors for BRAFV600-mutated MM) and immunotherapies (anti-CTLA-4 and anti-PD-1) has ...
Matilde Monti +4 more
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