Results 11 to 20 of about 4,892,488 (246)

Blastic Plasmacytoid Dendritic Cell Neoplasm [PDF]

Journal of Clinical Oncology, 2011
ABSTRACTBlastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare haematological malignancy that originates from the precursors of plasmacytoid dendritic cells. It commonly presents with findings isolated to the skin although it usually progresses to a leukaemic phase.
Jieping, Chen, Jingying, Zhou, Dabing, Qin, Shuangnian, Xu, Xiaochu, Yan   +4 more
core   +10 more sources

Blastic plasmacytoid dendritic cell neoplasm [PDF]

Anais Brasileiros de Dermatologia, 2013
Blastic plasmacytoid dendritic cell neoplasm is a rare and aggressive hematodermic neoplasia with frequent cutaneous involvement and leukemic dissemination. We report the case of a 76-year-old man with a 2 month history of violaceous nodules and a tumor with stony consistency, located on the head, and mandibular, cervical and supraclavicular ...
Lencastre, André, Cabete, Joana, João, Alexandre, Farinha, Pedro, Ferreira, Gilda, Lestre, Sara   +5 more
core   +7 more sources

Elucidation of plasmacytoid dendritic cell development [PDF]

, 2015
Most currently defined hematopoietic progenitor pools are heterogeneous, contributing to uncertainty regarding the development of certain blood cells.
Netravali, Ilka
core   +6 more sources

Different distribution patterns of plasmacytoid dendritic cells in discoid lupus erythematosus and lichen planopilaris demonstrated by CD123 immunostaining, [PDF]

Anais Brasileiros de Dermatologia, 2020
Background: Clinical and histological features may overlap between lichen planopilaris-associated and discoid lupus erythematosus-associated scarring alopecia.
Azadeh Rakhshan, Parviz Toossi, Maliheh Amani, Sahar Dadkhahfar, Arash Bagheri Hamidi   +4 more
doaj   +1 more source

Plasmacytoid dendritic cell neoplasms

Blood Research, 2023
Plasmacytoid dendritic cells (pDCs) are type I interferon-producing cells that modulate immune responses. There are two types of pDC neoplasms: 1) mature pDC proliferation (MPDCP) associated with myeloid neoplasm and 2) blastic pDC neoplasm (BPDCN). MPDCP is a clonal expansion of mature pDCs that is predominantly associated with chronic myelomonocytic ...
Lee, Yoo Jin, Kim, Youjin, Park, Sang Hyuk, Jo, Jae-Cheol   +3 more
openaire   +2 more sources

Plasmacytoid dendritic cells in the eye

Progress in Retinal and Eye Research, 2021
Plasmacytoid dendritic cells (pDCs) are a unique subpopulation of immune cells, distinct from classical dendritic cells. pDCs are generated in the bone marrow and following development, they typically home to secondary lymphoid tissues. While peripheral tissues are generally devoid of pDCs during steady state, few tissues, including the lung, kidney ...
Arsia Jamali, Brendan Kenyon, Gustavo Ortiz, Abdo Abou-Slaybi, Victor G. Sendra, Deshea L. Harris, Pedram Hamrah   +6 more
openaire   +3 more sources

A study on the correlation between plasmacytoid dendritic cells and lymph node metastasis in advanced gastric cancer [PDF]

Zhongguo aizheng zazhi
Background and purpose: Plasmacytoid dendritic cells are one of the key immune cells in the tumor microenvironment (TME), which can directly or indirectly regulate tumor related immune responses and play multiple roles in the development and metastasis ...
CHEN Zhanwei, WU Yaoqiang, WANG Yanping, ZHANG Dejian, YU Fuxiang
doaj   +3 more sources

Plasmacytoid dendritic cells and cancer [PDF]

Journal of Leukocyte Biology, 2011
ABSTRACTCancer develops in a complex microenvironment comprising cancer cells, stromal cells, and host immune cells with their soluble products. The counteracting host-protective and tumor-promoting roles of different immune cell populations have been elegantly clarified in the last decade by pertinent genetically modified mouse models.
VERMI, William, SONCINI, Matias Cristobal, Melocchi L, SOZZANI, Silvano, FACCHETTI, Fabio   +4 more
openaire   +3 more sources

Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells

Nature Communications, 2022
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematologic malignancy derived from the precursors of plasmacytoid dendritic cells.
Tianyu Cai, Agnès Gouble, Kathryn L. Black, Anna Skwarska, Ammar S. Naqvi, Deanne Taylor, Ming Zhao, Qi Yuan, Mayumi Sugita, Qi Zhang, Roman Galetto, Stéphanie Filipe, Antonio Cavazos, Lina Han, Vinitha Kuruvilla, Helen Ma, Connie Weng, Chang-Gong Liu, Xiuping Liu, Sergej Konoplev, Jun Gu, Guilin Tang, Xiaoping Su, Gheath Al-Atrash, Stefan Ciurea, Sattva S. Neelapu, Andrew A. Lane, Hagop Kantarjian, Monica L. Guzman, Naveen Pemmaraju, Julianne Smith, Andrei Thomas-Tikhonenko, Marina Konopleva   +32 more
doaj   +1 more source

Rapidly progressing blastic plasmacytoid dendritic cell neoplasm causing diffuse skin thickening: A case report with sequential computed tomography examinations

Radiology Case Reports, 2021
Blastic plasmacytoid dendritic cell neoplasm is a rare aggressive myeloid malignancy thought to be derived from precursor plasmacytoid dendritic cells. Rapid progression and poor prognosis have been known.
Kyohei Yoshioka, Ryo Kurokawa, Shiori Amemiya, Hiroaki Koyamaa, Kensuke Matsuda, Akira Honda, Mineo Kurokawa, Aya Shinozaki-Ushiku, Osamu Abe   +8 more
doaj   +1 more source