Results 11 to 20 of about 45,338 (267)

Role of plasmacytoid dendritic cells in vascular dysfunction in mice with renovascular hypertension [PDF]

Heliyon
Endothelial dysfunction and inflammation are clinically significant risk factors for cardiovascular diseases in hypertension. Although immune cells play a role in hypertension, the impact of plasmacytoid dendritic cells in established renovascular ...
Balaji Srinivas, Kiran Alluri, Nour-Eddine Rhaleb, Souad Belmadani, Khalid Matrougui   +4 more
doaj   +2 more sources

Crosspresentation: Plasmacytoid Dendritic Cells Are in the Business [PDF]

Immunity, 2007
Crosspriming and crosspresentation are performed by specialized subsets of dendritic cells. In this issue, Hoeffel et al. (2007) show that human plasmacytoid dendritic cells can crosspresent HIV-derived peptides conjugated to a lipopeptide or HIV ...
Colonna, Marco, Cella, Marina
core   +3 more sources

Blastic Plasmacytoid Dendritic Cell Neoplasm [PDF]

Journal of Clinical Oncology, 2011
ABSTRACTBlastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare haematological malignancy that originates from the precursors of plasmacytoid dendritic cells. It commonly presents with findings isolated to the skin although it usually progresses to a leukaemic phase.
Jieping, Chen, Jingying, Zhou, Dabing, Qin, Shuangnian, Xu, Xiaochu, Yan   +4 more
  +9 more sources

Distinct metabolic profiles of circulating plasmacytoid dendritic cells in systemic sclerosis patients stratified by clinical phenotypes [PDF]

Arthritis Research & Therapy
Background Plasmacytoid dendritic cells (pDCs) play a key role in systemic sclerosis (SSc) pathophysiology. However, despite the recognised importance of metabolic reprogramming for pDC function, their metabolic profile in SSc remains to be elucidated ...
Beatriz H. Ferreira, Carolina Mazeda, Eduardo Dourado, João L. Simões, Ana Rita Prata, Rafael J. Argüello, Iola F. Duarte, Philippe Pierre, Catarina R. Almeida   +8 more
doaj   +2 more sources

T Lymphoblastic Lymphoma Hiding in Mature Plasmacytoid Dendritic Cell Proliferation: A Case Report and Literature Review

Diagnostics, 2023
To the best of the author’s knowledge, studies of mature plasmacytoid dendritic cell proliferation associated with T lymphoblastic lymphoma were extremely rare in the literature.
Cong Deng, Beibei Gao, Tianli Wang, Xiaona Chang, Guixiang Xiao, Qin Xia, Huaxiong Pan, Xiu Nie   +7 more
doaj   +1 more source

Different distribution patterns of plasmacytoid dendritic cells in discoid lupus erythematosus and lichen planopilaris demonstrated by CD123 immunostaining, [PDF]

Anais Brasileiros de Dermatologia, 2020
Background: Clinical and histological features may overlap between lichen planopilaris-associated and discoid lupus erythematosus-associated scarring alopecia.
Azadeh Rakhshan, Parviz Toossi, Maliheh Amani, Sahar Dadkhahfar, Arash Bagheri Hamidi   +4 more
doaj   +1 more source

Plasmacytoid dendritic cell neoplasms

Blood Research, 2023
Plasmacytoid dendritic cells (pDCs) are type I interferon-producing cells that modulate immune responses. There are two types of pDC neoplasms: 1) mature pDC proliferation (MPDCP) associated with myeloid neoplasm and 2) blastic pDC neoplasm (BPDCN). MPDCP is a clonal expansion of mature pDCs that is predominantly associated with chronic myelomonocytic ...
Lee, Yoo Jin, Kim, Youjin, Park, Sang Hyuk, Jo, Jae-Cheol   +3 more
openaire   +2 more sources

Plasmacytoid dendritic cells in the eye

Progress in Retinal and Eye Research, 2021
Plasmacytoid dendritic cells (pDCs) are a unique subpopulation of immune cells, distinct from classical dendritic cells. pDCs are generated in the bone marrow and following development, they typically home to secondary lymphoid tissues. While peripheral tissues are generally devoid of pDCs during steady state, few tissues, including the lung, kidney ...
Arsia Jamali, Brendan Kenyon, Gustavo Ortiz, Abdo Abou-Slaybi, Victor G. Sendra, Deshea L. Harris, Pedram Hamrah   +6 more
openaire   +3 more sources

Plasmacytoid dendritic cells and cancer [PDF]

Journal of Leukocyte Biology, 2011
ABSTRACTCancer develops in a complex microenvironment comprising cancer cells, stromal cells, and host immune cells with their soluble products. The counteracting host-protective and tumor-promoting roles of different immune cell populations have been elegantly clarified in the last decade by pertinent genetically modified mouse models.
VERMI, William, SONCINI, Matias Cristobal, Melocchi L, SOZZANI, Silvano, FACCHETTI, Fabio   +4 more
openaire   +3 more sources

A study on the correlation between plasmacytoid dendritic cells and lymph node metastasis in advanced gastric cancer [PDF]

Zhongguo aizheng zazhi
Background and purpose: Plasmacytoid dendritic cells are one of the key immune cells in the tumor microenvironment (TME), which can directly or indirectly regulate tumor related immune responses and play multiple roles in the development and metastasis ...
CHEN Zhanwei, WU Yaoqiang, WANG Yanping, ZHANG Dejian, YU Fuxiang
doaj   +3 more sources