Results 21 to 30 of about 45,338 (267)

Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells

Nature Communications, 2022
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematologic malignancy derived from the precursors of plasmacytoid dendritic cells.
Tianyu Cai, Agnès Gouble, Kathryn L. Black, Anna Skwarska, Ammar S. Naqvi, Deanne Taylor, Ming Zhao, Qi Yuan, Mayumi Sugita, Qi Zhang, Roman Galetto, Stéphanie Filipe, Antonio Cavazos, Lina Han, Vinitha Kuruvilla, Helen Ma, Connie Weng, Chang-Gong Liu, Xiuping Liu, Sergej Konoplev, Jun Gu, Guilin Tang, Xiaoping Su, Gheath Al-Atrash, Stefan Ciurea, Sattva S. Neelapu, Andrew A. Lane, Hagop Kantarjian, Monica L. Guzman, Naveen Pemmaraju, Julianne Smith, Andrei Thomas-Tikhonenko, Marina Konopleva   +32 more
doaj   +1 more source

Rapidly progressing blastic plasmacytoid dendritic cell neoplasm causing diffuse skin thickening: A case report with sequential computed tomography examinations

Radiology Case Reports, 2021
Blastic plasmacytoid dendritic cell neoplasm is a rare aggressive myeloid malignancy thought to be derived from precursor plasmacytoid dendritic cells. Rapid progression and poor prognosis have been known.
Kyohei Yoshioka, Ryo Kurokawa, Shiori Amemiya, Hiroaki Koyamaa, Kensuke Matsuda, Akira Honda, Mineo Kurokawa, Aya Shinozaki-Ushiku, Osamu Abe   +8 more
doaj   +1 more source

ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia. [PDF]

PLoS Pathogens, 2011
Viral diseases of the respiratory tract, which include influenza pandemic, children acute bronchiolitis, and viral pneumonia of the elderly, represent major health problems.
Benjamin Bondue, Olivier Vosters, Patricia de Nadai, Stéphanie Glineur, Olivier De Henau, Souphalone Luangsay, Frédéric Van Gool, David Communi, Paul De Vuyst, Daniel Desmecht, Marc Parmentier   +10 more
doaj   +1 more source

Endothelial cell-derived microparticles induce plasmacytoid dendritic cell maturation: potential implications in inflammatory diseases

Haematologica, 2009
Background Increased circulating endothelial microparticles, resulting from vascular endothelium dysfunction, and plasmacytoid dendritic cell activation are both encountered in common inflammatory disorders.
Fanny Angelot, Estelle Seillès, Sabeha Biichlé, Yael Berda, Béatrice Gaugler, Joel Plumas, Laurence Chaperot, Françoise Dignat-George, Pierre Tiberghien, Philippe Saas, Francine Garnache-Ottou   +10 more
doaj   +1 more source

Monocytic and blastic plasmacytoid dendritic cell differentiation in acute leukemia with KMT2A rearrangement

eJHaem, 2023
Acute leukemia with KMT2A rearrangement shows a spectrum of immunophenotypic presentation, but blastic plasmacytoid dendritic cell differentiation is extremely rare.
Owen Xue, Choladda V. Curry, Hong Fang, Carlos E. Bueso‐Ramos, L. Jeffrey Medeiros, Wei Wang   +5 more
doaj   +1 more source

Contrariety of Human Bone Marrow Mesenchymal Stromal Cell Functionality in Modulating Circulatory Myeloid and Plasmacytoid Dendritic Cell Subsets

Biology, 2023
Mesenchymal Stromal Cells (MSCs) derived from bone marrow are widely tested in clinical trials as a cellular therapy for potential inflammatory disorders. The mechanism of action of MSCs in mediating immune modulation is of wide interest.
Crystal C. Uwazie, Tyler U. Faircloth, Rhett N. Parr, Yenamala U. Reddy, Peiman Hematti, Devi Rajan, Raghavan Chinnadurai   +6 more
doaj   +1 more source

Blocking TLR7- and TLR9-mediated IFN-α Production by Plasmacytoid Dendritic Cells Does Not Diminish Immune Activation in Early SIV Infection [PDF]

, 2013
Persistent production of type I interferon (IFN) by activated plasmacytoid dendritic cells (pDC) is a leading model to explain chronic immune activation in human immunodeficiency virus (HIV) infection but direct evidence for this is lacking.
Simon C Watkins, Normolle, D, Kader, M, Elizabeth R Wonderlich, Guiducci, C, Smith, Amanda P., Watkins, SC, Amanda P. Smith (437248), Normolle, Daniel, Watkins Simon C., Franck J. Barrat (437251), Smith Amanda P., Simon M Barratt-Boyes, Daniel Normolle, Daniel Normolle (437250), Barrat Franck J., Simon M. Barratt-Boyes (264203), Normolle Daniel, Wonderlich Elizabeth R., Franck J Barrat, Barratt-Boyes Simon M., Guiducci, Cristiana, Barrat, Franck J., Kader, Muhamuda, Guiducci Cristiana, Wonderlich, ER, Cristiana Guiducci, Barrat, FJ, Watkins, Simon C., Amanda P Smith, Barratt-Boyes, SM, Muhamuda Kader, Smith, AP, Wonderlich, Elizabeth R., Cristiana Guiducci (437249), Simon C. Watkins (39900), Barratt-Boyes, Simon M., Muhamuda Kader (437247), Elizabeth R. Wonderlich (270792), Kader Muhamuda   +39 more
core   +1 more source

Plasmacytoid Dendritic Cells in Tolerance [PDF]

, 2010
Dendritic cells (DC) are professional antigen-presenting cells (APCs) that modulate the outcome of the immune response toward immunity or tolerance. There are a large variety of DC subsets according to surface phenotype, function, and tissue distribution.
Eric, Gehrie, William, Van der Touw, Jonathan S, Bromberg, Jordi C, Ochando   +3 more
openaire   +2 more sources

Plasmacytoid Dendritic Cells [PDF]

Transplant International, 2009
Plasmacytoid dendritic cells (PDCs) have perplexed pathologists for decades, undergoing multiple adjustments in nomenclature as their lineage and functions have been characterized. Although PDCs account for less than 0.1% of peripheral blood mononuclear cells, they serve as a principal source of interferon-alpha and are also known as interferon-I ...
Boor, Patrick, Metselaar, Herold J., de Jonge, Sarina, van der Laan, Luc J., Kwekkeboom, Jaap   +4 more
openaire   +4 more sources

A case report of blastic plasmacytoid dendritic cell neoplasm in a hispanic child

Leukemia Research Reports, 2021
Plasmacytoid dendritic cell neoplasms are aggressive and rare hematologic malignancies characterized by clonal expansion of plasmacytoid dendritic cells with frequent cutaneous involvement.
Katy Ordoñez Tanchiva, Pamela Contreras Chavez, Silvana Lucero Loli Guevara, Carlos Rodrigo Quispe Vicuña, Neharika Bhardwaj, Frederick Lansigan, Erik Deconinck   +6 more
doaj   +1 more source