Results 21 to 30 of about 4,892,488 (246)

ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia. [PDF]

PLoS Pathogens, 2011
Viral diseases of the respiratory tract, which include influenza pandemic, children acute bronchiolitis, and viral pneumonia of the elderly, represent major health problems.
Benjamin Bondue, Olivier Vosters, Patricia de Nadai, Stéphanie Glineur, Olivier De Henau, Souphalone Luangsay, Frédéric Van Gool, David Communi, Paul De Vuyst, Daniel Desmecht, Marc Parmentier   +10 more
doaj   +1 more source

Endothelial cell-derived microparticles induce plasmacytoid dendritic cell maturation: potential implications in inflammatory diseases

Haematologica, 2009
Background Increased circulating endothelial microparticles, resulting from vascular endothelium dysfunction, and plasmacytoid dendritic cell activation are both encountered in common inflammatory disorders.
Fanny Angelot, Estelle Seillès, Sabeha Biichlé, Yael Berda, Béatrice Gaugler, Joel Plumas, Laurence Chaperot, Françoise Dignat-George, Pierre Tiberghien, Philippe Saas, Francine Garnache-Ottou   +10 more
doaj   +1 more source

Monocytic and blastic plasmacytoid dendritic cell differentiation in acute leukemia with KMT2A rearrangement

eJHaem, 2023
Acute leukemia with KMT2A rearrangement shows a spectrum of immunophenotypic presentation, but blastic plasmacytoid dendritic cell differentiation is extremely rare.
Owen Xue, Choladda V. Curry, Hong Fang, Carlos E. Bueso‐Ramos, L. Jeffrey Medeiros, Wei Wang   +5 more
doaj   +1 more source

Contrariety of Human Bone Marrow Mesenchymal Stromal Cell Functionality in Modulating Circulatory Myeloid and Plasmacytoid Dendritic Cell Subsets

Biology, 2023
Mesenchymal Stromal Cells (MSCs) derived from bone marrow are widely tested in clinical trials as a cellular therapy for potential inflammatory disorders. The mechanism of action of MSCs in mediating immune modulation is of wide interest.
Crystal C. Uwazie, Tyler U. Faircloth, Rhett N. Parr, Yenamala U. Reddy, Peiman Hematti, Devi Rajan, Raghavan Chinnadurai   +6 more
doaj   +1 more source

Irradiation-Induced CD62L Shedding in Human Plasmacytoid Dendritic Cells Depends on ADAM17 and p38 MAPK. [PDF]

Immunology
Human plasmacytoid dendritic cell‐based vaccines efficiently migrate from blood to lymph nodes and prime naive T cells in humanised mice. Irradiation‐induced CD62L shedding, mediated by p38 MAP kinase and ADAM17, is involved in the regulation of PDC migration to secondary lymphoid organs in this model.
Leplus E, Kacher J, Hannani D, Vayssiere G, Molens JP, Laulanier K, Georgess D, Josserand V, Saas P, Planel S, Chaperot L, Plumas J.   +11 more
europepmc   +2 more sources

Innate sensing of HIV-infected cells [PDF]

, 2011
Cell-free HIV-1 virions are poor stimulators of type I interferon (IFN) production. We examined here how HIV-infected cells are recognized by plasmacytoid dendritic cells (pDCs) and by other cells.
Richard E. Randall, Randall, Richard E, Mustapha Si-Tahar, Helen K W Law, Julien Pothlichet, Plumas, Joel, Lepelley, Alice, Mammano, Fabrizio, Helen K. W. Law, Richard E Randall, Schwartz, Olivier, Albert, Matthew L, Albert, Matthew L., Louis, Stephanie, Laurence Chaperot, Chaperot, Laurence, Stéphanie Louis, Pothlichet, Julien, Olivier Schwartz, Si-Tahar, Mustapha, Sourisseau, Marion, Schilte, Clementine, Law, Helen K. W., Law, Helen K W, Marion Sourisseau, Joël Plumas, Alice Lepelley, Clémentine Schilte, Fabrizio Mammano, Matthew L Albert, Matthew L. Albert, Randall, Richard Edward, Randall, Richard Edward; id_orcid   +32 more
core   +2 more sources

Plasmacytoid Dendritic Cells in Tolerance [PDF]

, 2010
Dendritic cells (DC) are professional antigen-presenting cells (APCs) that modulate the outcome of the immune response toward immunity or tolerance. There are a large variety of DC subsets according to surface phenotype, function, and tissue distribution.
Eric, Gehrie, William, Van der Touw, Jonathan S, Bromberg, Jordi C, Ochando   +3 more
openaire   +2 more sources

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Blocking TLR7- and TLR9-mediated IFN-α Production by Plasmacytoid Dendritic Cells Does Not Diminish Immune Activation in Early SIV Infection [PDF]

, 2013
Persistent production of type I interferon (IFN) by activated plasmacytoid dendritic cells (pDC) is a leading model to explain chronic immune activation in human immunodeficiency virus (HIV) infection but direct evidence for this is lacking.
Simon C Watkins, Normolle, D, Kader, M, Elizabeth R Wonderlich, Guiducci, C, Smith, Amanda P., Watkins, SC, Amanda P. Smith (437248), Normolle, Daniel, Watkins Simon C., Franck J. Barrat (437251), Smith Amanda P., Simon M Barratt-Boyes, Daniel Normolle, Daniel Normolle (437250), Barrat Franck J., Simon M. Barratt-Boyes (264203), Normolle Daniel, Wonderlich Elizabeth R., Franck J Barrat, Barratt-Boyes Simon M., Guiducci, Cristiana, Barrat, Franck J., Kader, Muhamuda, Guiducci Cristiana, Wonderlich, ER, Cristiana Guiducci, Barrat, FJ, Watkins, Simon C., Amanda P Smith, Barratt-Boyes, SM, Muhamuda Kader, Smith, AP, Wonderlich, Elizabeth R., Cristiana Guiducci (437249), Simon C. Watkins (39900), Barratt-Boyes, Simon M., Muhamuda Kader (437247), Elizabeth R. Wonderlich (270792), Kader Muhamuda   +39 more
core   +2 more sources

The use of wavelength modulated Raman spectroscopy in label-free identification of T lymphocyte subsets, natural killer cells and dendritic cells [PDF]

, 2015
This work was funded by a Cancer Research United Kingdom, Engineering and Physical Sciences Research Council (grant EP/J01771X/1), Medical Research Council and Department of Health England Imaging Programme (MC, MM KD), and by A European Union FAMOS ...
Barbosa, Joao, Campbell, Elaine Catherine, Naomi McReynolds (741700), Michael Mazilu (426524), Dholakia, Kishan, Kishan Dholakia, João Barbosa (741701), Simon J. Powis (319937), Elaine C. Campbell (319934), Mazilu Michael, McReynolds Naomi, Dholakia Kishan, McReynolds, Naomi, Simon J Powis, Campbell Elaine C., Powis Simon J., Elaine C Campbell, Mingzhou Chen, Naomi McReynolds, Kishan Dholakia (426528), Chen Mingzhou, João Barbosa, Mingzhou Chen (741699), Barbosa João, Michael Mazilu, Chen, Mingzhou, Mazilu, Michael, Powis, Simon John, Chen, Mingzhou; id_orcid, Powis, Simon John; id_orcid   +29 more
core   +2 more sources