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Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a highly malignant hematological tumor derived from the precursor cells of plasmacytoid dendritic cells.
CHEN Xiaojun +4 more
doaj +1 more source
Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development [PDF]
Dendritic cells (DCs) in the thymus (tDCs) are predominantly accumulated in the medulla and contribute to the establishment of self-tolerance. However, how the medullary accumulation of tDCs is regulated and involved in self-tolerance is unclear. We show
Ishimaru, N. +36 more
core +1 more source
Murine thymic plasmacytoid dendritic cells [PDF]
AbstractWe report herein heterogeneous murine thymic cell subsets expressing CD11c and B220 (CD45R). The CD11c+B220+ subset expresses Ly6Chigh and MHC class IIlow in contrast with previously described thymic DC (CD11c+B220– cells). Freshly isolated thymic CD11c+B220+ cells show typical plasmacytoid morphology which differentiates to mature DC, in vitro
Tomoyuki, Okada +5 more
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Blastic plasmacytoid dendritic cell neoplasm [PDF]
Blastic plasmacytoid dendritic cell neoplasm is an uncommon, aggressive hematologic neoplasm carrying a poor prognosis with a median survival of one year, making early detection vital. Patients present with a number of characteristic cutaneous manifestations and are treated with chemotherapy and hematopoietic stem cell transplantation, which may ...
Lasheras-Pérez MA +2 more
+8 more sources
Plasmacytoid dendritic cells are crucial in Bifidobacterium adolescentis-mediated inhibition of Yersinia enterocolitica infection. [PDF]
In industrialized countries bacterial intestinal infections are commonly caused by enteropathogenic Enterobacteriaceae. The interaction of the microbiota with the host immune system determines the adequacy of an appropriate response against pathogens. In
Alexandra Wittmann +2 more
doaj +1 more source
Dendritic cells in human renal inflammation - Part II [PDF]
Dendritic cells (DCs) are bone marrow-derived professional antigen-presenting cells that act as master regulators of acquired and innate immune responses. Here, we review the available information on their role in human renal inflammation.
Elfriede Noessner +15 more
core +1 more source
Mobilizing plasmacytoid dendritic cells [PDF]
In this issue of Blood , Schroeder et al demonstrate striking mobilization of plasmacytoid dendritic cell progenitors (pre-pDCs) and mature plasmacytoid dendritic cells (pDCs) into the vascular compartment along with CD34 + hematopoietic progenitor cells following administration of single-agent plerixafor in sibling donors ...
openaire +2 more sources
A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes [PDF]
Copyright @ 2012, American Society for Microbiology.Human coronaviruses are associated with upper respiratory tract infections that occasionally spread to the lungs and other organs.
Lorin, V +18 more
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Background Blastic plasmacytoid dendritic cell neoplasm represents a rare type of hematologic malignancy that often manifests itself through various skin lesions. It commonly affects the elderly male population.
Fateme Salemi +5 more
doaj +1 more source
Chemokine receptor type 3 (CXCR3) plays an important role in CD8+ T cells migration during intracellular infections, such as Trypanosoma cruzi. In addition to chemotaxis, CXCR3 receptor has been described as important to the interaction between antigen ...
Camila Pontes Ferreira +9 more
doaj +1 more source

