Results 1 to 10 of about 121,512 (113)

Development and function of chicken XCR1+ conventional dendritic cells [PDF]

Frontiers in Immunology, 2023
Conventional dendritic cells (cDCs) are antigen-presenting cells (APCs) that play a central role in linking innate and adaptive immunity. cDCs have been well described in a number of different mammalian species, but remain poorly characterised in the ...
Zhiguang Wu, Barbara Shih, Barbara Shih, Joni Macdonald, Dominique Meunier, Kris Hogan, Cosmin Chintoan-Uta, Hazel Gilhooley, Tuanjun Hu, Mariana Beltran, Neil C. Henderson, Neil C. Henderson, Helen M. Sang, Mark P. Stevens, Michael J. McGrew, Adam Balic, Adam Balic   +16 more
doaj   +2 more sources

Dendritic Cell Vaccines for Cancer Immunotherapy: The Role of Human Conventional Type 1 Dendritic Cells

Pharmaceutics, 2020
Throughout the last decades, dendritic cell (DC)-based anti-tumor vaccines have proven to be a safe therapeutic approach, although with inconsistent clinical results. The functional limitations of ex vivo monocyte-derived dendritic cells (MoDCs) commonly
João Calmeiro, Mylène A. Carrascal, Adriana Ramos Tavares, Daniel Alexandre Ferreira, Célia Gomes, Amílcar Falcão, Maria Teresa Cruz, Bruno Miguel Neves   +7 more
doaj   +3 more sources

Resveratrol pretreatment mitigates LPS-induced acute lung injury by regulating conventional dendritic cells’ maturation and function [PDF]

Open Life Sciences, 2021
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a severe syndrome lacking efficient therapy and resulting in high morbidity and mortality.
Guo Bingnan, Peng Yigen, Gu Yuting, Zhong Yi, Su Chenglei, Liu Lin, Chai Dafei, Song Tengfei, Zhao Ningjun, Yan Xianliang, Xu Tie   +10 more
doaj   +2 more sources

Type 1 conventional dendritic cells regulate innate immunity during fungal pneumonia [PDF]

mBio
Aspergillus fumigatus is a ubiquitous mold that is the primary etiological agent of invasive pulmonary aspergillosis (IPA), a severe lung infection in immunocompromised patients with extreme mortality.
Pari M. Dhruva, Thomas E. Draper, Camille A. Chiller, MaryJane Jones, Chad Steele   +4 more
doaj   +2 more sources

RARα supports the development of Langerhans cells and langerin-expressing conventional dendritic cells

Nature Communications, 2018
Langerhans cells (LC) and langerin-expressing conventional dendritic cells are made from distinct progenitors and enriched in the distinct microenvironments of the skin.
Seika Hashimoto-Hill, Leon Friesen, Sungtae Park, Suji Im, Mark H. Kaplan, Chang H. Kim   +5 more
doaj   +2 more sources

Sequential activation of conventional and plasmacytoid dendritic cells in autoimmune pancreatitis and systemic lupus erythematosus: similarities and dissimilarities

Frontiers in Immunology
Type 1 autoimmune pancreatitis (AIP) and systemic lupus erythematosus (SLE) are caused by type I IFNs secreted by plasmacytoid dendritic cells (pDCs).
Akane Hara, Tomohiro Watanabe, Kosuke Minaga, Ken Kamata, Warren Strober, Masatoshi Kudo   +5 more
doaj   +3 more sources

Single cell RNA sequencing reveals distinct clusters of Irf8-expressing pulmonary conventional dendritic cells. [PDF]

Front Immunol, 2023
Jirmo AC, Grychtol R, Gaedcke S, Liu B, DeStefano S, Happle C, Halle O, Monteiro JT, Habener A, Breiholz OD, DeLuca D, Hansen G.   +11 more
europepmc   +2 more sources

Regulation of the Migration of Distinct Dendritic Cell Subsets

Frontiers in Cell and Developmental Biology, 2021
Dendritic cells (DCs), a class of antigen-presenting cells, are widely present in tissues and apparatuses of the body, and their ability to migrate is key for the initiation of immune activation and tolerogenic immune responses.
Meng Feng, Shuping Zhou, Yong Yu, Qinghong Su, Xiaofan Li, Wei Lin   +5 more
doaj   +1 more source

OVA-PEG-R848 nanocapsules stimulate neonatal conventional and plasmacytoid dendritic cells

Frontiers in Pediatrics, 2022
Childhood mortality represents a major issue with 5. 3 million worldwide deaths of children under 5 years of age in 2019. Approximately half of those deaths can be attributed to easily preventable, infectious diseases.
Sebastian Wirsching, Marina Machtakova, Frauke Borgans, Frauke Borgans, Leah Pretsch, Michael Fichter, Michael Fichter, Michael Fichter, Maximiliano L. Cacicedo, Héloïse Thérien-Aubin, Héloïse Thérien-Aubin, Katharina Landfester, Stephan Gehring   +12 more
doaj   +1 more source

Human Dendritic Cell Subset Isolation by Magnetic Bead Sorting: A Protocol to Efficiently Obtain Pure Populations

Bio-Protocol, 2023
Dendritic cells have been investigated for cell-based immunotherapy for various applications. The low abundance of dendritic cells in blood hampers their clinical application, resulting in the use of monocyte-derived dendritic cells as an alternative ...
Georgina Flórez-Grau, Jorge Cuenca Escalona, Helena Lacasta-Mambo, Daphne Roelofs, Johanna Bödder, Ruben Beuk, Gerty Schreibelt, I Jolanda de Vries   +7 more
doaj   +1 more source