Results 1 to 10 of about 4,660,604 (252)

Zika virus infection differentially affects genome-wide transcription in neuronal cells and myeloid dendritic cells. [PDF]

PLoS ONE, 2020
Zika virus (ZIKV) is an emerging mosquito-borne flavivirus that has attracted global attention and international awareness. ZIKV infection exhibits mild symptoms including fever and pains; however, ZIKV has recently been shown to be related to increased ...
Tamina Park, Myung-Gyun Kang, Seung-Hwa Baek, Chang Hoon Lee, Daeui Park   +4 more
doaj   +2 more sources

Single-Cell Analysis of Brain Arteriovenous Malformations Reveals Pro-Angiogenic Myeloid Programs [PDF]

Brain Sciences
Background/Objectives: Brain arteriovenous malformations (bAVMs) are complex cerebrovascular lesions that carry a substantial risk of intracranial hemorrhage, yet the biological mechanisms underlying vascular remodeling remain incompletely understood. As
Benjamin Beyersdorf, Stefanos Voglis, Zsolt Kulcsar, Luca Regli, Menno R. Germans   +4 more
doaj   +2 more sources

Contrariety of Human Bone Marrow Mesenchymal Stromal Cell Functionality in Modulating Circulatory Myeloid and Plasmacytoid Dendritic Cell Subsets

Biology, 2023
Mesenchymal Stromal Cells (MSCs) derived from bone marrow are widely tested in clinical trials as a cellular therapy for potential inflammatory disorders. The mechanism of action of MSCs in mediating immune modulation is of wide interest.
Crystal C. Uwazie, Tyler U. Faircloth, Rhett N. Parr, Yenamala U. Reddy, Peiman Hematti, Devi Rajan, Raghavan Chinnadurai   +6 more
doaj   +1 more source

Oral chronic graft-versus-host disease: analysis of dendritic cells subpopulations [PDF]

Anais Brasileiros de Dermatologia, 2014
The graft-versus-host disease is the major cause of morbidity and mortality in patients who have undergone hematopoietic stem cell transplantation. Aiming at contributing to the understanding of the role of myeloid and plasmacytoid dendritic cells, and ...
Clara Marino Espricigo Botari, Adauto José Ferreira Nunes, Mair Pedro de Souza, Érica Sinara Lenharo Orti-Raduan, Ana Gabriela Salvio   +4 more
doaj   +2 more sources

Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells

Haematologica, 2010
Background The immunoregulatory enzyme indoleamine 2,3-dioxygenase, which catalyzes the conversion of tryptophan into kynurenine, is expressed in a significant subset of patients with acute myeloid leukemia, resulting in the inhibition of T-cell ...
Antonio Curti, Sara Trabanelli, Chiara Onofri, Michela Aluigi, Valentina Salvestrini, Darina Ocadlikova, Cecilia Evangelisti, Sergio Rutella, Raimondo De Cristofaro, Emanuela Ottaviani, Michele Baccarani, Roberto M. Lemoli   +11 more
doaj   +1 more source

Identification of Clec4b as a novel regulator of bystander activation of auto-reactive T cells and autoimmune disease.

PLoS Genetics, 2020
The control of chronic inflammation is dependent on the possibility of limiting bystander activation of autoreactive and potentially pathogenic T cells.
Liselotte Bäckdahl, Mike Aoun, Ulrika Norin, Rikard Holmdahl   +3 more
doaj   +1 more source

Twenty-four-color full spectrum flow cytometry panel for minimal residual disease detection in acute myeloid leukemia

Open Medicine, 2023
Full spectrum flow cytometry brings a breakthrough for minimal residual disease (MRD) detection in acute myeloid leukemia (AML). We aimed to explore the role of a new panel in MRD detection. We established a 24-color full-spectrum flow cytometry panel. A
Chen Man, Fu Minjing, Gong Meiwei, Gao Yajing, Wang Aixian, Zhao Wei, Wu Xueying, Wang Hui   +7 more
doaj   +1 more source

Lactotransferrin-Cre reporter mice trace neutrophils, monocytes/macrophages and distinct subtypes of dendritic cells

Haematologica, 2014
Considerable effort has been expended to identify genes that account for myeloid lineage commitment and development. However, currently available non-invasive mouse models utilize myeloid-specific reporters that are significantly expressed in ...
Boris Kovacic, Andrea Hoelbl-Kovacic, Katrin M. Fischhuber, Nicole R. Leitner, Dagmar Gotthardt, Emilio Casanova, Veronika Sexl, Mathias Müller   +7 more
doaj   +1 more source

SUBTYPE CHARACTERICS OF DENDRITIC CELLS FROM PERIPHERAL BLOOD OF PATIENTS WITH RHEUMATOID ARTHRITIS

Медицинская иммунология, 2014
. Characteristics of myeloid and plasmacytoid dendritic cells from peripheral blood were studied in healthy donors and patients with rheumatoid arthritis (RA).
S. A. Falaleeva, V. V. Kurilin, N. S. Shkaruba, O. A. Chumasova, A. E. Sizikov, S. V. Sennikov   +5 more
doaj   +1 more source

Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics

eLife, 2021
Innate immune cellular effectors are actively consumed during systemic inflammation, but the systemic traffic and the mechanisms that support their replenishment remain unknown.
Juana Serrano-Lopez, Shailaja Hegde, Sachin Kumar, Josefina Serrano, Jing Fang, Ashley M Wellendorf, Paul A Roche, Yamileth Rangel, Leolene J Carrington, Hartmut Geiger, H Leighton Grimes, Sanjiv Luther, Ivan Maillard, Joaquin Sanchez-Garcia, Daniel T Starczynowski, Jose A Cancelas   +15 more
doaj   +1 more source