Results 21 to 30 of about 4,990,718 (300)

Myeloid blood dendritic cells and monocyte-derived dendritic cells differ in their endocytosing capability [PDF]

Human Immunology, 2012
Human dendritic cells (DCs) constitute a heterogeneous population of antigen-presenting cells characterized by a unique capacity to stimulate naïve T cells. The functions of DCs depend on the particular subset and in this study we compare two types of myeloid DCs: freshly isolated blood mDCs and in vitro generated monocyte-derived DCs (MoDCs), in their
Andersson, Linda, Cirkic, Emina, Hellman, Peter, Eriksson, Håkan   +3 more
openaire   +4 more sources

Alpha (v) integrins license regulatory T cells to apoptotic cells and self-associated antigens [PDF]

, 2010
Defects in apoptotic cell clearance are thought to contribute to autoimmunity by failure to induce tolerance, coupled with accumulation of immunogenic material.
Paidassi, Helena, Lacy-Hulbert, Adam, Helena Païdassi, Adam Lacy-Hulbert, Mridu Acharya, Acharya, Mridu   +5 more
core   +1 more source

Dendritic cells and myeloid leukaemias: plasticity and commitment in cell differentiation [PDF]

British Journal of Haematology, 2007
SummaryDendritic cells (DCs) are key antigen‐presenting cells (APCs), which link innate and adaptive immunity, ultimately activating antigen‐specific T cells. This review examines the relationship between the acute and chronic myeloid leukaemias and cells with DC properties.
Jane, Rasaiyaah, Kwee, Yong, David R, Katz, Paul, Kellam, Benjamin M, Chain   +4 more
openaire   +2 more sources

Dendritic cells in human renal inflammation - Part II [PDF]

, 2011
Dendritic cells (DCs) are bone marrow-derived professional antigen-presenting cells that act as master regulators of acquired and innate immune responses. Here, we review the available information on their role in human renal inflammation.
Elfriede Noessner, Noessner, Elfriede, Segerer, S., Noessner, E, Stephan Segerer, Nößner, E., Peter J. Nelson, Lindenmeyer, Maja, Segerer, Stephan, Lindenmeyer, M., Lindenmeyer, M, Nelson, P.J., Maja Lindenmeyer, Nelson, Peter J., Segerer, S, Nelson, P J   +15 more
core   +1 more source

Negative impact of proteinuria on circulating myeloid dendritic cells. [PDF]

Clin Exp Nephrol, 2019
A decrease in absolute numbers (abs.) of circulating dendritic cells (DCs) and recruitment into target organs has been reported, but whether the level of proteinuria associates with circulating DC abs. has not been clarified.We conducted a cross-sectional study of 210 patients with kidney disease aged 21-96 years who were admitted to our hospital for ...
Ikeda M, Terashima R, Yamada T, Suyama M, Yokote S, Nakao M, Yamamoto I, Hirano K, Okonogi H, Yamamoto H, Yokoo T.   +10 more
europepmc   +4 more sources

A dendrite in every pie [PDF]

Virulence, 2012
Dendritic cells (DC) are a heterogeneous population of innate immune cells that are fundamental to initiating responses against invading pathogens and regulating immune responses. Myeloid DC (mDC) act as a bridge between the innate and adaptive immune response during virus infections but their role in immunity to human immunodeficiency virus (HIV ...
Wonderlich, Elizabeth R., Barratt-Boyes, Simon M.   +1 more
openaire   +2 more sources

Direct evidence that leukemic cells present HLA-associated immunogenic peptides derived from the BCR-ABL b3a2 fusion protein [PDF]

, 2001
The BCR-ABL oncogene is central in the pathogenesis of chronic myeloid leukemia (CML). Here, tandem nanospray mass spectrometry was used to demonstrate cell surface HLA- associated expression of the BCR-ABL peptide KQSSKALQR on class I-negative CIVIL ...
Lill, JR, Christmas, SE, Wang, LH, Macintyre, AR, Bourdon, A, Hill, SC, Rojas, J, Dodi, IA, Bonner, PLR, Aubert, G, Creaser, CS, Clark, RE, Rees, RC, Travers, PJ, Madrigal, JA   +14 more
core   +1 more source

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes [PDF]

, 2012
Copyright @ 2012, American Society for Microbiology.Human coronaviruses are associated with upper respiratory tract infections that occasionally spread to the lungs and other organs.
Lorin, V, Tangy, Frédéric, Vabret, Astrid, Vidalain, Pierre-Olivier, Tangy, F, Escriou, Nicolas, Millet, J, Escriou, N, Law, H, Albert, ML, Millet, Jean, K., Nal, B, Law, Helen, Albert, Matthew L, Vabret, A, Nal, Béatrice, Lorin, Valérie, Vidalain, PO, Mesel-Lemoine, Mariana   +18 more
core   +1 more source

Skin-derived dendritic cells acquire and degrade the scrapie agent following in vitro exposure [PDF]

, 2005
The accumulation of the scrapie agent in lymphoid tissues following inoculation via the skin is critical for efficient neuroinvasion, but how the agent is initially transported from the skin to the draining lymph node is not known. Langerhans cells (LCs)
Hopkins, John, Mabbott, Neil; id_orcid, John Hopkins, Joanne Mohan, Mohan, Joanne, Neil A. Mabbott   +5 more
core   +1 more source

Dendritic cell responses to Plasmodium falciparum in a malaria-endemic setting

Malaria Journal, 2021
Background Plasmodium falciparum causes the majority of malaria cases worldwide and children in sub-Saharan Africa are the most vulnerable group affected.
Triniti C. Turner, Charles Arama, Aissata Ongoiba, Safiatou Doumbo, Didier Doumtabé, Kassoum Kayentao, Jeff Skinner, Shanping Li, Boubacar Traore, Peter D. Crompton, Anton Götz   +10 more
doaj   +1 more source