Results 11 to 20 of about 4,990,718 (300)
Journal of Leukocyte Biology, 1999 Abstract There is considerable but as yet incomplete evidence for two developmental lineages of dendritic cells: a myeloid lineage shared with phagocytes and a lymphoid lineage shared with T cells. The two corresponding functional states, which may not require the existence of two formal lineages, are that myeloid dendritic cells capture
R M, Steinman, K, Inaba
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Isolation of Myeloid Dendritic Cells and Epithelial Cells from Human Thymus [PDF]
Journal of Visualized Experiments, 2013 In this protocol we provide a method to isolate dendritic cells (DC) and epithelial cells (TEC) from the human thymus. DC and TEC are the major antigen presenting cell (APC) types found in a normal thymus and it is well established that they play distinct roles during thymic selection.
Christina, Stoeckle +5 more
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Characteristics of Tip-DCs and MDSCs and their potential role in leishmaniasis [PDF]
Frontiers in Microbiology, 2012 Since the first description of dendritic cells (DCs) by Ralph Marvin Steinman and Zanvil Alexander Cohn in 1973, the myeloid lineage of leukocytes was investigated intensively.
Maximilian eSchmid +2 more
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Dendritic cell ontogeny: A human dendritic cell lineage of myeloid origin [PDF]
Proceedings of the National Academy of Sciences, 1997 Dendritic cells (DC) have been thought to represent a family of closely related cells with similar functions and developmental pathways. The best-characterized precursors are the epidermal Langerhans cells, which migrate to lymphoid organs and become activated DC in response to inflammatory stimuli.
J, Olweus +6 more
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Dendritic Cell-Based Immunotherapy for Myeloid Leukemias [PDF]
Frontiers in Immunology, 2013 Acute and chronic myeloid leukemia (AML, CML) are hematologic malignancies arising from oncogene-transformed hematopoietic stem/progenitor cells known as leukemia stem cells (LSCs). LSCs are selectively resistant to various forms of therapy including irradiation or cytotoxic drugs.
Christian Martijn Schürch +4 more
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Characterisation of T cell defects in acute myeloid leukaemia [PDF]
, 2009 PhDUnderstanding the immune system in patients with cancer and how it interacts with malignant cells is critical for the development of successful immunotherapeutic strategies at a time when novel cancer treatment approaches are required.
Le Dieu, Helen Rifca
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Interaction of Rotavirus with Human Myeloid Dendritic Cells [PDF]
Journal of Virology, 2005 ABSTRACTWe have previously shown that very few rotavirus (RV)-specific T cells that secrete gamma interferon circulate in recently infected and seropositive adults and children. Here, we have studied the interaction of RV with myeloid immature (IDC) and mature dendritic cells (MDC) in vitro.
Carlos F, Narváez +2 more
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Myeloid dendritic cells in HIV-1 infection [PDF]
Current Opinion in HIV and AIDS, 2011 Myeloid dendritic cells (mDCs) are pivotal players in HIV-1 infection. They promote transmission and spread and at the same time are critical for recognizing HIV-1 and initiating immune responses to fight infection. Notably, their immunostimulatory capabilities can be harnessed to design better HIV-1 vaccines. In this review, advances in these areas of
Nina, Derby +2 more
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Increased Blood Myeloid Dendritic Cells and Dendritic Cell-Poietins in Langerhans Cell Histiocytosis [PDF]
The Journal of Immunology, 2005 Abstract Langerhans cell histiocytosis (LCH), previously known as histiocytosis X, is a reactive proliferative disease of unknown pathogenesis. Current therapies are based on nonspecific immunosuppression. Because multiple APCs, including Langerhans cells and macrophages, are involved in the lesion formation, we surmised that LCH is a ...
Alexandre, Rolland +6 more
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Regulatory immune cells in transplantation. [PDF]
, 2012 Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control both the innate immune response triggered by the injured ...
Bushell, Andrew +5 more
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