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Neonatal dendritic cells

Vaccine, 1998
The capacity of lymphoid dendritic cells from human cord blood or adult peripheral blood to support a mixed leukocyte reaction in cord blood and adult T cells has been compared. Cord blood dendritic cells have a limited ability to induce either adult or cord blood T cells to proliferate in response to typical concentration of phytohemagglutinin or ...
R E, Petty, D W, Hunt
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Dendritic Cells

The Cancer Journal, 2011
Dendritic cells (DCs) control the initiation and differentiation of T cells. In the steady state, DCs mediate tolerance. To achieve immunization, the tolerogenic function of DCs must be switched off by inducing their maturation with appropriate "adjuvants." Dendritic cells form a system composed of distinct subsets that differ in their expression of ...
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Intrathyroidal Dendritic Cells*

The Journal of Clinical Endocrinology & Metabolism, 1988
The presence, marker pattern, and ultrastructure of antigen-presenting dendritic cells were studied in normal thyroid glands from 9 subjects (6 obtained at surgery; 3 at autopsy) and in the thyroid glands form 13 patients with Graves' hyperthyroidism, 10 patients with simple nontoxic goiter, and 1 patient with Hashimoto's disease (all obtained at ...
P J, Kabel   +4 more
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Dendritic Cell Vaccines

2016
Exploitation of the patient's own immune system to induce antitumor immune responses using dendritic cell (DC) immunotherapy has been established in early clinical trials as a safe and promising therapeutic approach for cancer. However, their limited success in larger clinical trials highlights the need to optimize DC vaccine preparations. This chapter
Rachel Lubong, Sabado   +2 more
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Myeloid dendritic cells

Journal of Leukocyte Biology, 1999
Abstract There is considerable but as yet incomplete evidence for two developmental lineages of dendritic cells: a myeloid lineage shared with phagocytes and a lymphoid lineage shared with T cells. The two corresponding functional states, which may not require the existence of two formal lineages, are that myeloid dendritic cells capture
R M, Steinman, K, Inaba
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Regulatory Dendritic Cells

2017
Dendritic cells (DCs) comprise heterogeneous subsets, functionally classified into conventional DCs (cDCs) and plasmacytoid DCs (pDCs). DCs are considered to be essential antigen (Ag)-presenting cells (APCs) that play crucial roles in activation and fine-tuning of innate and adaptive immunity under inflammatory conditions, as well as induction of ...
Katsuaki, Sato   +3 more
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Mucosal Dendritic Cells

Annual Review of Immunology, 2007
The internal surfaces of the human body are covered by distinct types of epithelial cells and mucus-secreting cells. The mucosal surfaces serve many vital functions, such as respiration (nasal passage and lung), absorption (gastrointestinal tract), excretion (lung, urinary tract, large intestine), and reproduction (reproductive tract).
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Interstitial Dendritic Cells

International Reviews of Immunology, 1990
Interstitial dendritic cells (IDC) were first identified in the interstitium of non-lymphoid organs as leucocytes which stained intensely with anti-MHC class II antibodies. These cells have been identified in several species including man, and can be distinguished from tissue macrophages by their immunological phenotype and cytochemical and functional ...
D N, Hart, J L, McKenzie
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Follicular Dendritic Cells and Dendritic Cell Nomenclature

1993
In the 10 years since the last nomenclature committee on dendritic cells met (Tew, Thorbecke and Steinman, J. Reticuloendothelial Society 31:371, 1982), considerable evidence has accumulated supporting the concept that Langerhans cells, interdigitating cells, and veiled cells are the same cell in different stages of maturation. It also appears that the
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Dendritic cell immunotherapy

Annals of the New York Academy of Sciences, 2013
The U.S. Food and Drug Administration's approval of the first cell‐based immunotherapy has rejuvenated interest in the field. Early clinical trials have established the ability of dendritic cell (DC) immunotherapy to exploit a patient's own immune system to induce antitumor immune responses.
Rachel Lubong, Sabado, Nina, Bhardwaj
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