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Seminars in Cell & Developmental Biology, 2018
Dendritic cells (DC) are professional antigen presenting cells comprising a variety of subsets, as either resident or migrating cells, in lymphoid and non-lymphoid organs. In the steady state DC continually process and present antigens on MHCI and MHCII, processes that are highly upregulated upon activation.
Timothy Patton +3 more
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Dendritic cells (DC) are professional antigen presenting cells comprising a variety of subsets, as either resident or migrating cells, in lymphoid and non-lymphoid organs. In the steady state DC continually process and present antigens on MHCI and MHCII, processes that are highly upregulated upon activation.
Timothy Patton +3 more
openaire +3 more sources
American Journal of Respiratory and Critical Care Medicine, 2005
Dendritic cells (DCs) are leukocytes that are emerging as chief orchestrators of immune responses. The crucial task of DCs is the continuous surveillance of antigen-exposed sites throughout the body, and their unique responsibility is to decide whether to present sampled antigen in an immunogenic or tolerogenic way.
Romain Pauwels, Karim Vermaelen
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Dendritic cells (DCs) are leukocytes that are emerging as chief orchestrators of immune responses. The crucial task of DCs is the continuous surveillance of antigen-exposed sites throughout the body, and their unique responsibility is to decide whether to present sampled antigen in an immunogenic or tolerogenic way.
Romain Pauwels, Karim Vermaelen
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Immunology Letters, 1988
Dendritic cells (DC) are potent at presenting viral antigens in the initiation of both primary and secondary responses. DC in the lymph nodes draining the site of infection with HSV express surface antigen and can stimulate proliferation of sensitised lymphocytes. In secondary stimulation, nonresponsiveness in cytotoxic T cell assays of cells from mice
Stella C. Knight, Steven E. Macatonia
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Dendritic cells (DC) are potent at presenting viral antigens in the initiation of both primary and secondary responses. DC in the lymph nodes draining the site of infection with HSV express surface antigen and can stimulate proliferation of sensitised lymphocytes. In secondary stimulation, nonresponsiveness in cytotoxic T cell assays of cells from mice
Stella C. Knight, Steven E. Macatonia
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2009
Dendritic cells (DCs) are sparsely but widely distributed cells of hematopoietic origin that are specialized for the capture, processing and presentation of antigens to T cells. They also play an important role in innate immune function. DCs are heterogeneous and differ in location, migratory pathways and immunologic function.
Pai, Saparna, Thomas, Ranjeny
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Dendritic cells (DCs) are sparsely but widely distributed cells of hematopoietic origin that are specialized for the capture, processing and presentation of antigens to T cells. They also play an important role in innate immune function. DCs are heterogeneous and differ in location, migratory pathways and immunologic function.
Pai, Saparna, Thomas, Ranjeny
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2010
Dendritic cells (DCs) are specialized antigen-presenting cells that orchestrate innate and adaptive immune responses. The intestinal mucosa contains numerous DCs that are highly specialized in function. Mucosal DCs display a unique response to toll-like receptor ligands, are capable of driving immunoglobulin isotype switching to IgA, can imprint gut ...
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Dendritic cells (DCs) are specialized antigen-presenting cells that orchestrate innate and adaptive immune responses. The intestinal mucosa contains numerous DCs that are highly specialized in function. Mucosal DCs display a unique response to toll-like receptor ligands, are capable of driving immunoglobulin isotype switching to IgA, can imprint gut ...
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The Cancer Journal, 2011
Dendritic cells (DCs) control the initiation and differentiation of T cells. In the steady state, DCs mediate tolerance. To achieve immunization, the tolerogenic function of DCs must be switched off by inducing their maturation with appropriate "adjuvants." Dendritic cells form a system composed of distinct subsets that differ in their expression of ...
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Dendritic cells (DCs) control the initiation and differentiation of T cells. In the steady state, DCs mediate tolerance. To achieve immunization, the tolerogenic function of DCs must be switched off by inducing their maturation with appropriate "adjuvants." Dendritic cells form a system composed of distinct subsets that differ in their expression of ...
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Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes
Nature, 2022S. Maschalidi +12 more
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Dendritic Cells and Dendritic Cell Subsets
2016© 2016 Elsevier Ltd All rights reserved. Dendritic cells (DCs) are specialized antigen-presenting cells that may arise naturally from common DC progenitors in the bone marrow or develop from monocytes during inflammation. Migratory DCs arrive in lymph nodes (LNs) from the tissues, while LN-resident DCs are recruited from the blood.
Collin M, Haniffa M
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Blood monocytes: development, heterogeneity, and relationship with dendritic cells.
Annual Review of Immunology, 2009Monocytes are circulating blood leukocytes that play important roles in the inflammatory response, which is essential for the innate response to pathogens.
C. Auffray, M. Sieweke, F. Geissmann
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Intrathyroidal Dendritic Cells*
The Journal of Clinical Endocrinology & Metabolism, 1988The presence, marker pattern, and ultrastructure of antigen-presenting dendritic cells were studied in normal thyroid glands from 9 subjects (6 obtained at surgery; 3 at autopsy) and in the thyroid glands form 13 patients with Graves' hyperthyroidism, 10 patients with simple nontoxic goiter, and 1 patient with Hashimoto's disease (all obtained at ...
M. de Haan +4 more
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