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Antigen presentation and T cell stimulation by dendritic cells.
Annual Review of Immunology, 2002Dendritic cells take up antigens in peripheral tissues, process them into proteolytic peptides, and load these peptides onto major histocompatibility complex (MHC) class I and II molecules.
P. Guermonprez +4 more
semanticscholar +1 more source
Vaccine, 1998
The capacity of lymphoid dendritic cells from human cord blood or adult peripheral blood to support a mixed leukocyte reaction in cord blood and adult T cells has been compared. Cord blood dendritic cells have a limited ability to induce either adult or cord blood T cells to proliferate in response to typical concentration of phytohemagglutinin or ...
David W. C. Hunt, Ross E. Petty
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The capacity of lymphoid dendritic cells from human cord blood or adult peripheral blood to support a mixed leukocyte reaction in cord blood and adult T cells has been compared. Cord blood dendritic cells have a limited ability to induce either adult or cord blood T cells to proliferate in response to typical concentration of phytohemagglutinin or ...
David W. C. Hunt, Ross E. Petty
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2016
Exploitation of the patient's own immune system to induce antitumor immune responses using dendritic cell (DC) immunotherapy has been established in early clinical trials as a safe and promising therapeutic approach for cancer. However, their limited success in larger clinical trials highlights the need to optimize DC vaccine preparations. This chapter
Marcia Meseck +2 more
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Exploitation of the patient's own immune system to induce antitumor immune responses using dendritic cell (DC) immunotherapy has been established in early clinical trials as a safe and promising therapeutic approach for cancer. However, their limited success in larger clinical trials highlights the need to optimize DC vaccine preparations. This chapter
Marcia Meseck +2 more
openaire +3 more sources
International Journal of Hematology, 2005
The migration of dendritic cells (DCs) to lymph nodes (LNs) is pivotal to the establishment of the immune response. DCs have been proved to pass through the afferent lymphatic pathway to enter LNs from the peripheral tissues after they have scanned for self or nonself antigens. In response to danger signals, both myeloid and plasmacytoid DC precursors (
Hiroyuki Yoneyama +2 more
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The migration of dendritic cells (DCs) to lymph nodes (LNs) is pivotal to the establishment of the immune response. DCs have been proved to pass through the afferent lymphatic pathway to enter LNs from the peripheral tissues after they have scanned for self or nonself antigens. In response to danger signals, both myeloid and plasmacytoid DC precursors (
Hiroyuki Yoneyama +2 more
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2017
Dendritic cells (DCs) comprise heterogeneous subsets, functionally classified into conventional DCs (cDCs) and plasmacytoid DCs (pDCs). DCs are considered to be essential antigen (Ag)-presenting cells (APCs) that play crucial roles in activation and fine-tuning of innate and adaptive immunity under inflammatory conditions, as well as induction of ...
Hideaki Takagi +7 more
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Dendritic cells (DCs) comprise heterogeneous subsets, functionally classified into conventional DCs (cDCs) and plasmacytoid DCs (pDCs). DCs are considered to be essential antigen (Ag)-presenting cells (APCs) that play crucial roles in activation and fine-tuning of innate and adaptive immunity under inflammatory conditions, as well as induction of ...
Hideaki Takagi +7 more
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Dermatologic Clinics, 1990
The dendritic shape of a given cell is by no means indicative of its origin and function. This is exemplified best by the ontogenetic and functional heterogeneity of dendritic cells in the skin. Even when focusing on bone marrow-derived dendritic cells, the mammalian skin contains at least three distinct lineages of dendritic cells, including Ia ...
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The dendritic shape of a given cell is by no means indicative of its origin and function. This is exemplified best by the ontogenetic and functional heterogeneity of dendritic cells in the skin. Even when focusing on bone marrow-derived dendritic cells, the mammalian skin contains at least three distinct lineages of dendritic cells, including Ia ...
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Dendritic cells and the control of immunity
Nature, 1998J. Banchereau, R. Steinman
semanticscholar +1 more source
Annual Review of Immunology, 2007
The internal surfaces of the human body are covered by distinct types of epithelial cells and mucus-secreting cells. The mucosal surfaces serve many vital functions, such as respiration (nasal passage and lung), absorption (gastrointestinal tract), excretion (lung, urinary tract, large intestine), and reproduction (reproductive tract).
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The internal surfaces of the human body are covered by distinct types of epithelial cells and mucus-secreting cells. The mucosal surfaces serve many vital functions, such as respiration (nasal passage and lung), absorption (gastrointestinal tract), excretion (lung, urinary tract, large intestine), and reproduction (reproductive tract).
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2005
(Uploaded by Plazi for the Bat Literature Project) This chapter discusses dendritic cells (DCs). Surrogate markers to measure adaptive T cell immunity include cytotoxic T lymphocyte responses, cytokine production by T lymphocytes and more recently, antigen-specific T lymphocytes determined by tetramer/monomer technology. However, T lymphocyte responses
Field, K., Vuckovic, S., Hart, D.N.J.
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(Uploaded by Plazi for the Bat Literature Project) This chapter discusses dendritic cells (DCs). Surrogate markers to measure adaptive T cell immunity include cytotoxic T lymphocyte responses, cytokine production by T lymphocytes and more recently, antigen-specific T lymphocytes determined by tetramer/monomer technology. However, T lymphocyte responses
Field, K., Vuckovic, S., Hart, D.N.J.
openaire +2 more sources