A compact, wireless neural stimulator featuring a novel tapping inductor enables selective and independent stimulation of the motor cortex in rats via a single receiver coil. This minimally invasive system effectively reduces neuropathic pain through targeted cortical activation, offering a new avenue for bioelectronic pain therapies and advancing ...
Jeongju Moon+9 more
wiley +1 more source
Continuous volumetric imaging via an optical phase-locked ultrasound lens
In vivo imaging at high spatiotemporal resolution is key to the understanding of complex biological systems. We integrated an optical phase-locked ultrasound lens into a two-photon fluorescence microscope and achieved microsecond-scale axial scanning ...
Cui, M.+7 more
core +1 more source
Glia selectively approach synapses on thin dendritic spines
This paper examines the relationship between the morphological modality of 189 dendritic spines and the surrounding astroglia using full three-dimensional reconstructions of neuropil fragments.
N. Medvedev+5 more
semanticscholar +1 more source
Pyramidal Cells with Different Densities of Dendritic Spines in the Cortex of the Mouse [PDF]
Almut Schüz
openalex +1 more source
Biomimetic Mineralization of Keratin Scaffolds for Enamel Regeneration
Keratin‐based films guide biomimetic enamel remineralization by promoting organized hydroxyapatite growth under physiological conditions. Advanced biophysical characterization confirms keratin's structural adaptability and mineral ions‐binding affinity, supporting mineral nucleation and hierarchical crystal assembly. This study establishes keratin as a
Sara Gamea+19 more
wiley +1 more source
CREB Regulates Experience-Dependent Spine Formation and Enlargement in Mouse Barrel Cortex
Experience modifies synaptic connectivity through processes that involve dendritic spine rearrangements in neuronal circuits. Although cAMP response element binding protein (CREB) has a key function in spines changes, its role in activity-dependent ...
Annabella Pignataro+3 more
doaj +1 more source
Long-Term In Vivo Imaging of Dendritic Spines in the Hippocampus Reveals Structural Plasticity
Hippocampal function is important for learning and memory. During memory processing, hippocampal CA1 neurons play a crucial role by integrating excitatory synaptic input from CA3 and the entorhinal cortex.
Ligang Gu+7 more
semanticscholar +1 more source
Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation [published erratum appears in J Neurosci 1992 Aug;12(8):following table of contents] [PDF]
Kristen M. Harris, Jensen Fe, B Tsao
openalex +1 more source
Engineering Complexity: Advances in 3D Breast Cancer Models for Precision Oncology
In vitro breast cancer models that closely mimic the complex biological and cellular interactions within the tumor microenvironment hold strong promise for enhancing our understanding of tumor progression, immune system behavior, and resistance to therapies, which are essential for developing personalized cancer treatments. Abstract Engineered in vitro
Wonwoo Jeong, Sang Jin Lee
wiley +1 more source
Summary: Dendritic spines are protrusions on dendrites forming the postsynaptic aspect of excitatory connections within the brain. Spine morphology is associated with synaptic functional strength and the spatial regulation of protein nanodomains within ...
Kathryn J. Bjornson, Michael E. Cahill
doaj +1 more source