Results 151 to 160 of about 43,830 (285)

Sodium pump organization in dendritic spines [PDF]

, 2016
Hans Blom, Kristoffer Bernhem, Hjalmar Brismar   +2 more
openalex   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source

Transient Photoactivation of Rac1 Induces Persistent Structural LTP Independent of CaMKII in Hippocampal Dendritic Spines. [PDF]

eNeuro
Saneyoshi T, Suematsu C, Hayashi Y.
europepmc   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Calcium dynamics in small spaces: Lessons learned from modeling in dendritic spines. [PDF]

Biophys J
McCabe KJ, Hernández Mesa M, Rangamani P.   +2 more
europepmc   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Compromised hepatic bilirubin clearance drives depressive symptoms via regulating microglial engulfment of dendritic spines. [PDF]

J Neuroinflammation
Sun S, Li M, Ma J, He K, Wang L, Li C, Liu X, Zhang S, Yin T, Yang M, Yang X, Zhang J, Xu C, Li Z, Wang S, Zhu H.   +15 more
europepmc   +1 more source

Tweety-homolog 1 protein overexpression alters dendritic complexity and dendritic spine morphology of CA1 and CA3 pyramidal neurons in organotypic slices in vitro

Malgorzata Gorniak, Dorota Nowicka, Aleksandra Kaliszewska, Szymon Łęski, Katarzyna Łukasiuk   +4 more
openalex   +1 more source

Author response: Subunit exchange enhances information retention by CaMKII in dendritic spines

, 2018
Dilawar Singh, Upinder S. Bhalla
openalex   +1 more source

A Non‐Mitophagy Activity of BNIP3L/NIX in Amygdala Glutamatergic Neurons is Essential for Contextual Fear Memory Formation

Advanced Science, EarlyView.
Contextual fear conditioning induces BNIP3L‐dependent mitochondrial fission in glutamatergic neurons of the BLA, independently of mitophagy. Loss of BNIP3L elevates Drp1Ser637 phosphorylation, thereby suppressing mitochondrial fission, compromising ATP production, and attenuating excitatory synaptic transmission.
Xingxian Zhang, Xinlei Mo, Xinyu Zhou, Xiaoliang Liu, Guizhi Li, Songhui Hu, Yangyang Lu, Chenze Zhu, Jinxi Feng, Zhitong Chen, Weiwei Hu, Yihui Cui, Zhong Chen, Xiangnan Zhang   +13 more
wiley   +1 more source